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List of works by Merja Perälä

558 Systematic functional analysis of microRNAs by transfection of 1129 miRNAs into prostate cancer cells

A new simple cell-based homogeneous time-resolved fluorescence QRET technique for receptor-ligand interaction screening

scientific article

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

scientific article

Correction: miRNA-mRNA Integrated Analysis Reveals Roles for miRNAs in Primary Breast Tumors

scientific article published in PLoS ONE

Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors

scientific article published on 8 October 2013

Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint

scientific article

Distinct roles of AKT isoforms in regulating β1-integrin activity, migration, and invasion in prostate cancer

scientific article

Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response

scientific article published on 21 March 2017

Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

scientific article

HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation

scientific article

Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis

scientific article

High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells

scientific article (publication date: 2013)

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

scientific article

High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth

scientific article

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

scientific article

Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact

scientific article

Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells

scientific article

Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c

scientific article

Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors

scientific article

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

scientific article

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

scientific article published on 9 September 2013

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer

scientific article published on 14 September 2011

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling

scientific article

Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea.

scientific article

MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth

scientific article published on 21 March 2015

P26. MicroRNA expression profiling and functional screening in bone metastatic breast cancer cells

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

scientific article

Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

scientific article

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue

scientific article published on 19 October 2015

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

scientific article

The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells

scientific article published on 24 November 2012

miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors

scientific article (publication date: 22 February 2011)

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