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List of works by Takuro Niidome

A Solid-in-Oil Dispersion of Gold Nanorods Can Enhance Transdermal Protein Delivery and Skin Vaccination

scientific article published on 13 December 2010

A colorimetric assay of protein kinase activity based on peptide-induced coagulation of gold nanorods

scientific article published on 8 September 2011

A gene-delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer.

scientific article published on 15 June 2010

A hydrophilic polymer grafted with a histone tail peptide as an artificial gene regulator

scientific article published on 14 May 2011

A novel double-coating carrier produced by solid-in-oil and solid-in-water nanodispersion technology for delivery of genes and proteins into cells.

scientific article published on 9 May 2012

A novel protease activity assay using a protease-responsive chaperone protein

scientific article published on 31 March 2009

A peptide microarray fabricated on a non-fouling phosphatidylcholine-polymer-coated surface for a high-fidelity analysis of a cellular kinome

scientific article published in January 2013

A peptide microarray for the detection of protein kinase activity in cell lysate.

scientific article published on March 2007

A peptide sequence controls the physical properties of nanoparticles formed by peptide-polymer conjugates that respond to a protein kinase a signal

scientific article

A polyion complex nanogel

scientific article published on 19 September 2012

A protein kinase assay based on FRET between quantum dots and fluorescently-labeled peptides

scientific article

A protein kinase signal-responsive gene carrier modified RGD peptide.

scientific article published on 12 September 2006

A quantitative peptide array for evaluation of protein kinase activity

scientific article

A short peptide is a protein kinase C (PKC) alpha-specific substrate.

scientific article

A simple set-and-mix assay for screening of protein kinase inhibitors in cell lysates ⬇️

scientific article published on July 6, 2011

A syngeneic hepatocellular carcinoma model rapidly and simply prepared using a hydrodynamics-based procedure.

scientific article published on 25 June 2008

Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase beta.

scientific article published on December 1999

An intracellular kinase signal-responsive gene carrier for disordered cell-specific gene therapy.

scientific article published on 23 November 2005

Analysis of elements in the substrate required for processing by mitochondrial processing peptidase

scientific article published on 01 December 1995

Antibacterial Activity of Arg/Pro-Rich Bactenecin 5 Model Peptides and Their Interaction with Phospholipid Membranes

article

Antibacterial activity of bactenecin 5 fragments and their interaction with phospholipid membranes

scientific article published in June 2001

Antibacterial activity of peptides derived from the C-terminal region of a hemolytic lectin, CEL-III, from the marine invertebrate Cucumaria echinata

scientific article published in January 2004

Artificial viruses and their application to gene delivery. Size-controlled gene coating with glycocluster nanoparticles

scientific article published in March 2003

Biodistribution and Tumor Localization of PEG-Modified Dendritic Poly(L-Lysine) Oligonucleotide Complexes ⬇️

scientific article published on 12 January 2012

Branched polyethylenimine-based PKCα-responsive gene carriers

scientific article published on 25 June 2013

Carbohydrate-dependent hemolytic activity of the conjugate composed of a C-type lectin, CEL-I, and an amphiphilic alpha-helical peptide, 4(3)-beta Ala2

scientific article published on 01 July 1999

Cellular signal-specific peptide substrate is essential for the gene delivery system responding to cellular signals.

scientific article published on 13 September 2009

Chain length of cationic alpha-helical peptide sufficient for gene delivery into cells

scientific article published on 01 September 1999

Characterization of gene expression regulation using D-RECS polymer by enzymatic reaction for an effective design of enzyme-responsive gene regulator

scientific article published on 15 January 2010

Characters of dendritic poly(L-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro

scientific article published in February 2004

Colorimetric enzymatic activity assay based on noncrosslinking aggregation of gold nanoparticles induced by adsorption of substrate peptides.

scientific article

Combination of bubble liposomes and high-intensity focused ultrasound (HIFU) enhanced antitumor effect by tumor ablation

scientific article published in January 2014

Comparison of ovalbumin and ovalbumin epitope peptide for transdermal delivery and vaccination mediated by the photothermal effect of gold nanorods

scientific article published on 19 July 2017

Conversion of rod-shaped gold nanoparticles to spherical forms and their effect on biodistribution in tumor-bearing mice

scientific article published on 11 October 2012

Correlation between phosphorylation ratios by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis and radioactivities by radioactive assay ⬇️

scientific article published on August 26, 2011

Creating a unique environment for selecting reactive enzymes with DNA: 'Sticky' binding of oligocation-grafted polymers to DNA

scientific article published on 21 December 2011

Cytosolic soluble proteins induce DNA release from DNA--gene carrier complexes

scientific article

Design of polymeric carriers for cancer-specific gene targeting: utilization of abnormal protein kinase Calpha activation in cancer cells.

scientific article published on 18 October 2008

Design of temperature-responsive polymers with enhanced hysteresis: alpha,alpha-disubstituted vinyl polymers.

scientific article published in June 2010

Development of ErbB2-Targeting Liposomes for Enhancing Drug Delivery to ErbB2-Positive Breast Cancer

scientific article published on 24 June 2020

Development of polymeric drug delivery system for recognizing vascular endothelial dysfunction

scientific article published on 10 January 2008

Drug Release System Controlled by Near Infrared Light ⬇️

scientific article published on 01 January 2013

Drug delivery system based on responses to an HIV infectious signal.

scientific article

Effect of Chain Length of Cationic Model Peptides on Antibacterial Activity

article

Effect of amino acid substitution in amphiphilic α-helical peptides on peptide-phospholipid membrane interaction

scientific article published on 01 July 1999

Effect of introduction of chondroitin sulfate into polymer-peptide conjugate responding to intracellular signals.

scientific article published on 30 September 2011

Effect of peptide content on the regulation of transgene expression by protein kinase Cα-responsive linear polyethylenimine-peptide conjugates

scientific article published on 20 September 2014

Effect of the addition of diammonium citrate to alpha-cyano-4-hydroxycinnamic acid (CHCA) matrix for the detection of phosphorylated peptide in phosphorylation reactions using cell and tissue lysates.

scientific article

Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex

scientific article published on 28 March 2008

Effects of pulsed laser irradiation on gold-coated silver nanoplates and their antibacterial activity

scientific article published on 17 October 2017

Efficient delivery of siRNA using dendritic poly(L-lysine) for loss-of-function analysis

scientific journal article

Efficient delivery of signal-responsive gene carriers for disease-specific gene expression via bubble liposomes and sonoporation

scientific article published on 9 September 2017

Enhancement of Transdermal Protein Delivery by Photothermal Effect of Gold Nanorods Coated on Polysaccharide-based Hydrogel.

scientific article

Establishment of screening system toward discovery of kinase inhibitors using label-free on-chip phosphorylation assays.

scientific article published on 5 May 2009

Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging.

scientific article published on 15 December 2007

Fluorescent nanoparticles consisting of lipopeptides and fluorescein-modified polyanions for monitoring of protein kinase activity.

scientific article

Fluorescent polyion complex nanoparticle that incorporates an internal standard for quantitative analysis of protein kinase activity

scientific article published on 8 May 2014

Fluorometric detection of protein kinase Cα activity based on phosphorylation-induced dissociation of a polyion complex.

scientific article

Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier.

scientific article

Gene carrier showing all-or-none response to cancer cell signaling.

scientific article published on 11 September 2012

Gene therapy progress and prospects: nonviral vectors.

scientific article

Gene transfer into hepatoma cells mediated by galactose-modified alpha-helical peptides.

scientific article published in September 2000

Glycol Chitosan-Docosahexaenoic Acid Liposomes for Drug Delivery: Synergistic Effect of Doxorubicin-Rapamycin in Drug-Resistant Breast Cancer

scientific article published on 12 October 2019

Gold Coating of Silver Nanoplates for Enhanced Dispersion Stability and Efficient Antimicrobial Activity against Intracellular Bacteria

scientific article published on 23 August 2018

Gold Nanorods as Nanodevices for Bioimaging, Photothermal Therapeutics, and Drug Delivery

scientific article published on January 2017

Gold nanorods in an oil-base formulation for transdermal treatment of type 1 diabetes in mice

scientific article published on 23 May 2012

Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells.

scientific article published on 20 November 2003

Helicobacter pylori VacA, acting through receptor protein tyrosine phosphatase α, is crucial for CagA phosphorylation in human duodenum carcinoma cell line AZ-521

scientific article published on December 2016

Helicobacter pylori vacuolating cytotoxin binds to the 140-kDa protein in human gastric cancer cell lines, AZ-521 and AGS.

scientific article published on September 1997

Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule.

scientific article published on 4 February 2010

High-throughput colorimetric detection of tyrosine kinase inhibitors based on the aggregation of gold nanoparticles.

scientific article published in September 2007

Histidinylated poly-L-lysine-based vectors for cancer-specific gene expression via enhancing the endosomal escape.

scientific article published on 27 January 2014

Hyaluronic acid and its derivative as a multi-functional gene expression enhancer: protection from non-specific interactions, adhesion to targeted cells, and transcriptional activation

scientific article published on 27 March 2006

Hydrophobic cavity formed by oligopeptide for doxorubicin delivery based on dendritic poly(L-lysine).

scientific article

Impairment of glutathione metabolism in human gastric epithelial cells treated with vacuolating cytotoxin from Helicobacter pylori.

scientific article

Importance of hydrophobic region in amphiphilic structures of alpha-helical peptides for their gene transfer-ability into cells

scientific article published on 01 April 1998

Improvement in the colloidal stability of protein kinase-responsive polyplexes by PEG modification

scientific article published on 15 February 2012

In vitro gene transfection using dendritic poly(L-lysine).

scientific article

In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia

scientific article published on 21 August 2009

Inflammatory cell-specific transgene expression system responding to Ikappa-B kinase beta activation.

scientific article

Influence of lipophilic groups in cationic alpha-helical peptides on their abilities to bind with DNA and deliver genes into cells.

scientific article published on October 1999

Interaction of bundled Ser-rich amphiphilic peptides with phospholipid membranes

scientific article published on 01 August 1999

Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers

scholarly article by Yumiko Hori published in January 2001

Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity.

scientific article

Intracellular signal-responsive artificial gene regulation.

scientific article published on January 2006

Intracellular signal-responsive gene carrier for cell-specific gene expression

scientific article published on March 2005

Letter: correlation between phosphorylation ratios by matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis and enzyme kinetics.

scientific article

Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium

scientific article published on 01 February 2003

Long circulation of intravenously administered plasmid DNA delivered with dendritic poly(L-lysine) in the blood flow.

scientific article published on September 2004

Mass-tag technology responding to intracellular signals as a novel assay system for the diagnosis of tumor

scientific article published on 13 October 2006

Measurement of homogeneous kinase activity for cell lysates based on the aggregation of gold nanoparticles.

scientific article published on May 2007

Molecular cloning of the smaller subunit(P52) of rat liver mitochondrial processing protease.

scientific article published on January 1993

Molecular design of protein-based nanocapsules for stimulus-responsive characteristics.

scientific article published on 12 November 2008

Molecular mechanism of caspase-3-induced gene expression of polyplexes formed from polycations grafted with cationic substrate peptides.

scientific article

Monitoring protein kinase activity in cell lysates using a high-density peptide microarray.

scientific article

NFkappaB decoy delivery using dendritic poly(l-lysine) for treatment of endotoxin-induced hepatitis in mice.

scientific article

Nanoparticles of adaptive supramolecular networks self-assembled from nucleotides and lanthanide ions

scientific article

Nitroxyl radicals-modified dendritic poly(l-lysine) as a contrast agent for Overhauser-enhanced MRI.

scientific article

Novel poly(ethylene glycol) derivatives with carboxylic acid pendant groups: synthesis and their protection and enhancing effect on non-viral gene transfection systems.

scientific article published in January 2003

Novel receptor-mediated gene delivery system comprising plasmid/protamine/sugar-containing polyanion ternary complex

scientific article published on July 2004

Optimization of peptide density on microarray surface for quantitative phosphoproteomics.

scientific article published on January 2011

Orientational behavior of phospholipid membranes with mastoparan studied by 31P solid state NMR

scientific article published on 01 July 1999

Overall interaction of cytosolic proteins with the PEI/DNA complex

scientific article published on 9 January 2007

PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice

scientific article published on 30 September 2006

PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser

scientific article

Parallel and antiparallel dimers of magainin 2: their interaction with phospholipid membrane and antibacterial activity

scientific article

Peptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2)

scientific article

Peptide vector for gene delivery with high affinity for phosphatidylserine

scientific article published on 01 October 2006

Phosphorylation of Rho-associated kinase (Rho-kinase/ROCK/ROK) substrates by protein kinases A and C.

scientific article

Poly(ethylene glycol)-modified gold nanorods as a photothermal nanodevice for hyperthermia

scientific article published in January 2009

Polydispersity as a parameter for indicating the thermal stability of proteins by dynamic light scattering

scientific article published on 01 January 2010

Polyelectrolyte-coated gold nanorods and their biomedical applications.

scientific article

Protease D from the sarcocarp of honeydew melon fruit

scientific article published on 01 July 1993

Protein kinase C alpha-specific peptide substrate graft-type copolymer for cancer cell-specific gene regulation systems.

scientific article

Protein kinase Calpha-responsive polymeric carrier: its application for gene delivery into human cancers.

scientific article

Protein kinase substrate profiling with a high-density peptide microarray

scientific article published on November 2010

Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route.

scientific article

Rapid and selective determination of free chlorine in aqueous solution using electrophilic addition to styrene by gas chromatography/mass spectrometry.

scientific article published on 12 October 2012

Rapid and serum-insensitive endocytotic delivery of proteins using biotinylated polymers attached via multivalent hydrophobic anchors.

scientific article published on 31 December 2013

Regulation of Transgene Expression in Tumor Cells by Exploiting Endogenous Intracellular Signals.

scientific article published on 17 December 2008

Role of estrogenic compounds (diethylstibestrol, 17beta-estradiol, and bisphenol A) in the phosphorylation of substrate by protein kinase Calpha.

scientific article

Role of plasma as activator and cofactor in phosphorylation catalyzed by protein kinase C

scientific article published on 01 January 2008

Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cells

scientific article published on 31 May 2001

Selective depletion of cultured macrophages by magnetite nanoparticles modified with gelatin.

scientific article

Serum protein kinase Cα as a diagnostic biomarker of cancers.

scientific article

Short peptide motifs for long-lasting anchoring to the cell surface.

scientific article published on 12 November 2014

Small‐angle X‐ray scattering study on CEL‐III, a hemolytic lectin from Holothuroidea Cucumaria echinata, and its oligomer induced by the binding of specific carbohydrate ⬇️

scientific article published on September 1, 1997

Stabilization of cancer-specific gene carrier via hydrophobic interaction for a clear-cut response to cancer signaling.

scientific article published on 18 June 2013

Stable incorporation of gold nanorods into N-isopropylacrylamide hydrogels and their rapid shrinkage induced by near-infrared laser irradiation

scientific article published on 21 February 2007

Structural advantage of dendritic poly(L-lysine) for gene delivery into cells

scientific article published on 10 October 2006

Structure-Activity Relationship of Model Peptides Based on Pleurocidin, an Antibacterial Peptide

article published in 2003

Structure–activity relationship of an antibacterial peptide, maculatin 1.1, from the skin glands of the tree frog,Litoria genimaculata

scholarly article by Takuro Niidome published in June 2004

Surface plasmon resonance imaging measurements of caspase reactions on peptide microarrays

scientific article published on 5 December 2007

Syndiotactic poly(N-n-propylacrylamide) shows highly cooperative phase transition.

scientific article published on January 2009

The effects of PEG grafting level and injection dose on gold nanorod biodistribution in the tumor-bearing mice.

scientific article published on 16 June 2009

The forthcoming applications of gold nanoparticles in drug and gene delivery systems.

scientific article published on 11 December 2009

Time-dependent complex formation of dendritic poly(L-lysine) with plasmid DNA and correlation with in vitro transfection efficiencies

scientific article published in April 2003

Transgene regulation system responding to Rho associated coiled-coil kinase (ROCK) activation

scientific article

Tumor therapy by gene regulation system responding to cellular signal.

scientific article published on 19 August 2010

Unusually Large Hysteresis of Temperature-Responsive Poly(N-ethyl-2-propionamidoacrylamide) Studied by Microcalorimetry and FT-IR

scientific article published on 01 June 2010

Vacuolating cytotoxin purified fromHelicobacter pyloricauses mitochondrial damage in human gastric cells

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