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List of works by Speranza Donatella Rubattu

A Decrease of Brain MicroRNA-122 Level Is an Early Marker of Cerebrovascular Disease in the Stroke-Prone Spontaneously Hypertensive Rat.

scientific article

A Next-Generation Sequencing Approach to Identify Gene Mutations in Early- and Late-Onset Hypertrophic Cardiomyopathy Patients of an Italian Cohort.

scientific article published on 30 July 2016

A Survey on Blood Pressure Levels and Hypertension Control in a Sample of the Italian General Population

article

A differential expression of uncoupling protein-2 associates with renal damage in stroke-resistant spontaneously hypertensive rat/stroke-prone spontaneously hypertensive rat-derived stroke congenic lines

scientific article

A protective role of a cholesteryl ester transfer protein gene variant towards ischaemic stroke in Sardinians

article

A role of TNF-alpha gene variant on juvenile ischemic stroke: a case-control study

article

Abnormalities of sodium handling and of cardiovascular adaptations during high salt diet in patients with mild heart failure

scientific article published on 01 October 1993

Altered regulation of endothelin A receptor subtype in the cerebral arterioles in response to a Japanese-style diet, in stroke-prone hypertensive rats

scientific article published in January 2003

Altered structure, regulation, and function of the gene encoding the atrial natriuretic peptide in the stroke-prone spontaneously hypertensive rat

scientific article published on 01 November 1999

Aminoterminal natriuretic peptide as a determinant of PAI-1 levels in a sample of the adult male Italian population

article

An easy and reproducible parameter for the assessment of the pressure gradient in patients with aortic stenosis disease: A magnetic resonance study.

scientific article

Angiotensin II Receptor Blocker Neprilysin Inhibitor (ARNI): New Avenues in Cardiovascular Therapy.

scientific article published on 23 June 2015

Angiotensin II directly stimulates release of atrial natriuretic factor in isolated rabbit hearts

scientific article published on 01 January 1993

Angiotensin converting enzyme inhibition restores cardiac and hormonal responses to volume overload in patients with dilated cardiomyopathy and mild heart failure

scientific article published on 01 December 1992

Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.

scientific article published on July 1996

Association of a single nucleotide polymorphism of the NPR3 gene promoter with early onset ischemic stroke in an Italian cohort

scientific article published on 18 September 2012

Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.

scientific article published on 12 July 2006

Atrial natriuretic Peptide single nucleotide polymorphisms in patients with nonfamilial structural atrial fibrillation

scientific article published on 15 September 2013

Atrial natriuretic peptide (ANP) gene promoter variant and increased susceptibility to early development of hypertension in humans

scientific article published on 24 May 2007

Atrial natriuretic peptide and regulation of vascular function in hypertension and heart failure: implications for novel therapeutic strategies

scientific article published on June 2013

Atrial natriuretic peptide gene polymorphisms and risk of ischemic stroke in humans

scientific article (publication date: April 2004)

Blood levels of erythropoietin in congestive heart failure and correlation with clinical, hemodynamic, and hormonal profiles

scientific article published on 01 September 1994

C2238 ANP gene variant promotes increased platelet aggregation through the activation of Nox2 and the reduction of cAMP.

scientific article

C2238 atrial natriuretic peptide molecular variant is associated with endothelial damage and dysfunction through natriuretic peptide receptor C signaling.

scientific article

C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro

scientific article published on 31 December 2015

Circulating Leukocytes and Oxidative Stress in Cardiovascular Diseases: A State of the Art

scientific article published on 15 October 2019

Circulating biomarkers with preventive, diagnostic and prognostic implications in cardiovascular diseases.

scientific article published on 16 July 2011

Common genetic variants in selected Ca²⁺ signaling genes and the risk of appropriate ICD interventions in patients with heart failure.

scientific article published on 19 September 2013

Contribution of genetic factors to renal lesions in the stroke-prone spontaneously hypertensive rat.

scientific article

Correspondence

scientific article published on 01 November 1997

Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat

scientific article published on 01 April 2000

Determinants of N-terminal proatrial natriuretic peptide plasma levels in a survey of adult male population from Southern Italy.

scientific article published in August 2010

Dickkopf-3 Upregulates VEGF in Cultured Human Endothelial Cells by Activating Activin Receptor-Like Kinase 1 (ALK1) Pathway

scientific article published on 14 March 2017

Differential modulation of uncoupling protein 2 in kidneys of stroke-prone spontaneously hypertensive rats under high-salt/low-potassium diet.

scientific article

Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism

scientific article published on 10 May 2010

Effect of a regulatory mutation on the rat atrial natriuretic peptide gene transcription.

scientific article published on March 2002

Effects of one-year treatment with rilmenidine on systemic hypertension-induced left ventricular hypertrophy in hypertensive patients

scientific article

Epigenetic control of natriuretic peptides: implications for health and disease

scientific article published on 18 June 2020

Estradiol- and progesterone-related increases in the renin-aldosterone system: studies during ovarian stimulation and early pregnancy

scientific article published on 01 July 1994

Etiology and pathophysiology of stroke as a complex trait

scientific article

Evaluation of Systolic Properties in Hypertensive Patients With Different Degrees of Diastolic Dysfunction and Normal Ejection Fraction

scientific article published on 29 January 2009

Executive Summary of the 2018 Joint Consensus Document on Cardiovascular Disease Prevention in Italy

article

Failure of atrial natriuretic factor to increase with saline load in patients with dilated cardiomyopathy and mild heart failure ⬇️

scientific article published on November 1, 1991

Functional cross-talk between angiotensin II and epidermal growth factor receptors in NIH3T3 fibroblasts.

scientific article published on April 2002

Gene polymorphisms of the renin???angiotensin???aldosterone system and the risk of ischemic stroke

article

High natriuretic peptide levels and low DBP: companion markers of cardiovascular risk?

scientific article published in November 2014

Highest concentrations of prorenin and human chorionic gonadotropin in gestational sacs during early human pregnancy

scientific article published on 01 September 1992

Human coronary atherosclerosis modulates cardiac natriuretic peptide release.

scientific article

Hypertension and heart failure: role of neurohormonal mechanisms

scientific article

Hypertension and kidneys: unraveling complex molecular mechanisms underlying hypertensive renal damage

scientific article published on 27 June 2013

Hypovitaminosis D and organ damage in patients with arterial hypertension: a multicenter double blind randomised controlled trial of cholecalciferol supplementation (HYPODD) : study design, clinical procedures and treatment protocol

scientific article published on 14 March 2015

Impaired vasorelaxant responses to natriuretic peptides in the stroke-prone phenotype of spontaneously hypertensive rats

scientific article published in February 1998

In the search for stroke genes: a long and winding road

scientific article published on February 2004

Influence of hypercholesterolemia on adrenal steroid metabolism and electrolyte balance in spontaneously hypertensive rats

scientific article published on 01 November 1993

Intrarenal determinants of sodium retention in mild heart failure: effects of angiotensin-converting enzyme inhibition

scientific article published on 01 August 1997

Markers of Inflammation and Fibrosis Are Related to Cardiovascular Damage in Hypertensive Patients with Metabolic Syndrome

scientific article published on 01 July 2007

Mitochondrial Dysfunction Contributes to Hypertensive Target Organ Damage: Lessons from an Animal Model of Human Disease

scientific article

Modulatory role of angiotensin-II in the secretion of atrial natriuretic factor in rabbits

scientific article published on 01 May 1991

Molecular cloning and expression of rat kallistatin gene ⬇️

scientific article published on September 12, 1997

Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides.

scientific article published on 09 August 2011

NPR-C: a component of the natriuretic peptide family with implications in human diseases.

scientific article published on 19 June 2010

NT-proANP and NT-proBNP circulating levels as predictors of cardiovascular outcome following coronary stent implantation

scientific article

NT-proANP circulating level is a prognostic marker in stable ischemic heart disease.

scientific article

NT-proANP/ANP is a Determinant of Vascular Damage in Humans

NT-proatrial natriuretic peptide as a possible biomarker of cardiopulmonary involvement in sarcoidosis.

scientific article published on 5 January 2013

Natriuretic peptides and cardiovascular damage in the metabolic syndrome: molecular mechanisms and clinical implications

scientific article

Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis

scientific article

Natriuretic peptides in cardiovascular diseases: current use and perspectives

scientific article

Natriuretic peptides: an update on bioactivity, potential therapeutic use, and implication in cardiovascular diseases.

scientific article published on 08 May 2008

Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease

scientific journal article

New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart

scientific article

No association between chromosome 12p13 single nucleotide polymorphisms and early-onset ischemic stroke

scientific article published on 21 May 2010

Pathogenesis of chronic cardiorenal syndrome: is there a role for oxidative stress?

scientific article

Pathogenesis of target organ damage in hypertension: role of mitochondrial oxidative stress

scientific article

Phosphodiesterase 4D and 5-lipoxygenase activating protein genes and risk of ischemic stroke in Sardinians

scientific article

Phytochemical Compounds and Protection from Cardiovascular Diseases: A State of the Art

scientific article

Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population

article

Polypharmacy in heart failure patients.

scientific article published on June 2014

Prediction of long-term survival in chronic heart failure by multiple biomarker assessment: a 15-year prospective follow-up study

scientific article published on November 2010

Protective effects of Brassica oleracea sprouts extract toward renal damage in high-salt-fed SHRSP: role of AMPK/PPARα/UCP2 axis

scientific article

Pulmonary embolism in pregnancy

scientific article published on 01 April 2014

Reactive oxygen species-mediated effects on vascular remodeling induced by human atrial natriuretic peptide T2238C molecular variant in endothelial cells in vitro.

scientific article published in September 2009

Reciprocal congenic lines for a major stroke QTL on rat chromosome 1.

scientific article published on 11 July 2006

Reduced brain UCP2 expression mediated by microRNA-503 contributes to increased stroke susceptibility in the high-salt fed stroke-prone spontaneously hypertensive rat.

scientific article published on 22 June 2017

Reduced levels of N-terminal-proatrial natriuretic peptide in hypertensive patients with metabolic syndrome and their relationship with left ventricular mass

scientific article published on 01 April 2007

Regulation of aldosterone biosynthesis by adrenal renin is mediated through AT1 receptors in renin transgenic rats

scientific article published on 01 July 1995

Relation between urinary kallikrein excretion and blood pressure response to a single oral dose of captopril

scientific article published in January 1987

Renin as a biomarker of cardiovascular disease in clinical practice.

scientific article published on 06 March 2012

Resetting the neurohormonal balance in heart failure (HF): the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF

scientific article published on 5 April 2017

Role of DAMPs and of Leukocytes Infiltration in Ischemic Stroke: Insights from Animal Models and Translation to the Human Disease

scientific article published on 29 September 2020

Role of NOX2 in mediating doxorubicin-induced senescence in human endothelial progenitor cells

scientific article published on 12 May 2016

Role of angiotensin II AT 1 and AT 2 subtype receptors in the regulation of atrial natriuretic peptide expression in salt-restricted rats

scientific article published on 01 February 2000

Role of genetic factors in the etiopathogenesis of cerebrovascular accidents: from an animal model to the human disease.

scientific article published in October 2004

Role of the renin-angiotensin-aldosterone system and inflammatory processes in the development and progression of diastolic dysfunction.

scientific article published on March 2009

Role of tissue renin in the regulation of aldosterone biosynthesis in the adrenal cortex of nephrectomized rats

scientific article published on 01 November 1997

RyR2 Common Gene Variant G1886S and the Risk of Ventricular Arrhythmias in ICD Patients with Heart Failure

scientific article published in May 2015

Short-term efficacy of nifedipine in essential and renovascular hypertension.

scientific article

T2238C ANP gene variant and risk of recurrent acute coronary syndromes in an Italian cohort of ischemic heart disease patients.

scientific article published on 23 September 2014

T2238C Atrial Natriuretic Peptide Gene Variant and the Response to Antiplatelet Therapy in Stable Ischemic Heart Disease Patients.

scientific article published on 5 December 2017

The C2238/αANP variant is a negative modulator of both viability and function of coronary artery smooth muscle cells

scientific article

The Pl(A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: increased risk of ischemic stroke in high-risk patients.

scientific article published in March 2007

The direct renin inhibitor aliskiren improves vascular remodelling in transgenic rats harbouring human renin and angiotensinogen genes

article

The gene encoding atrial natriuretic peptide and the risk of human stroke

scientific article published on 01 October 1999

The reduction of NDUFC2 expression is associated with mitochondrial impairment in circulating mononuclear cells of patients with acute coronary syndrome

scientific article published on 14 February 2019

Tissue renin and prorenin increase in female cats during the reproductive cycle without commensurate changes in plasma, amniotic or ovarian follicular fluid ⬇️

scientific article published on 01 June 1991

Trypsin activation of human and cat prorenin: a comparative study.

scientific article

β2-Adrenergic Receptor Gene Polymorphisms and Risk of Ischemic Stroke

article

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