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List of works by Julien Boccard

A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein

scientific article

A consensus orthogonal partial least squares discriminant analysis (OPLS-DA) strategy for multiblock Omics data fusion

scientific article

A scoring approach for multi-platform acquisition in metabolomics

scientific article published on 10 January 2019

A steroidomic approach for biomarkers discovery in doping control.

scientific article published on 9 August 2011

An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments

scientific article published on 24 April 2019

An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus galloprovincialis

scientific article published in 2022

Analysis of basic compounds by supercritical fluid chromatography: Attempts to improve peak shape and maintain mass spectrometry compatibility

scientific article published on 03 September 2012

Analytical aspects in doping control: Challenges and perspectives

scientific article published on 06 August 2011

Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship.

scientific article

Applicability of Supercritical fluid chromatography-Mass spectrometry to metabolomics. II-Assessment of a comprehensive library of metabolites and evaluation of biological matrices

scientific article published on 07 March 2020

Assessing Susceptibility to Epilepsy in Three Rat Strains Using Brain Metabolic Profiling Based on HRMAS NMR Spectroscopy and Chemometrics

scientific article

Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

scientific article

Chemical Composition and Anti-Inflammatory Activity of the Decoction from Leaves of a Cultivated Specimen of Myracrodruon urundeuva

scholarly article

Choosing an Optimal Sample Preparation in Caulobacter crescentus for Untargeted Metabolomics Approaches

scientific article published on 20 September 2019

Combining the advantages of multilevel and orthogonal partial least squares data analysis for longitudinal metabolomics: Application to kidney transplantation

scientific article published on 23 November 2019

Comprehensive examination of the mouse lung metabolome following Mycobacterium tuberculosis infection using a multiplatform mass spectrometry approach

scientific article published on 14 April 2020

Comprehensive profiling and marker identification in non-volatile citrus oil residues by mass spectrometry and nuclear magnetic resonance

scientific article published on 01 November 2013

Cultivar, site or harvest date: the gordian knot of wine terroir

scientific article published on 17 April 2020

Development and validation of an UHPLC-MS/MS method for extended serum steroid profiling in female populations

scientific article published on 01 June 2020

Development of a two-step screening ESI-TOF-MS method for rapid determination of significant stress-induced metabolome modifications in plant leaf extracts: The wound response in Arabidopsis thaliana as a case study

article

Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach

scientific article published on 03 August 2013

DynaStI: A Dynamic Retention Time Database for Steroidomics.

scientific article published on 30 April 2019

Dynamics of Metabolite Induction in Fungal Co-cultures by Metabolomics at Both Volatile and Non-volatile Levels

scientific article published on 5 February 2018

Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

scientific article

Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis

Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High-Resolution Mass Spectrometry for Untargeted Metabolomics

scientific article published on 15 November 2020

Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations

scientific article published on 07 July 2015

Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least Squares

scientific article

Exploring blood alterations in chronic kidney disease and haemodialysis using metabolomics

scientific article published on 11 November 2020

Extracting Knowledge from MS Clinical Metabolomic Data: Processing and Analysis Strategies

scientific article published in January 2018

From a single steroid to the steroidome: trends and analytical challenges

scientific article published on 28 November 2020

Gaining Insights Into Metabolic Networks Using Chemometrics and Bioinformatics: Chronic Kidney Disease as a Clinical Model

scientific article published on 14 May 2021

Harnessing the complexity of metabolomic data with chemometrics

scientific article published in 2013

High-resolution mass spectrometry as an alternative detection method to tandem mass spectrometry for the analysis of endogenous steroids in serum

scientific article published on 18 March 2017

High-throughput identification of monoclonal antibodies after compounding by UV spectroscopy coupled to chemometrics analysis

scientific article published on 22 June 2016

Human urinary biomarkers of dioxin exposure: analysis by metabolomics and biologically driven data dimensionality reduction

scientific article

IEF pattern classification-derived criteria for the identification of epoetin-delta in urine

scientific article published in June 2010

Identification of a predictive metabolic signature of response to immune checkpoint inhibitors in non-small cell lung cancer: METABO-ICI clinical study protocol

scientific article published on 07 June 2021

Implementation of liquid chromatography-high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial

scientific article published on 02 January 2020

In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

scientific article published on 16 April 2019

Inhibition of enteric methanogenesis in dairy cows induces changes in plasma metabolome highlighting metabolic shifts and potential markers of emission

scientific article published on 24 September 2020

Insights on the Structural and Metabolic Resistance of Potato (Solanum tuberosum) Cultivars to Tuber Black Dot (Colletotrichum coccodes) ⬇️

scientific article published on 20 August 2020

Integrating metabolomic data from multiple analytical platforms for a comprehensive characterisation of lemon essential oils

Iterative weighting of multiblock data in the orthogonal partial least squares framework

scientific article

Knowledge discovery in metabolomics: an overview of MS data handling

scientific article

Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports.

scientific article

MS-based Plant Metabolomic Approaches for Biomarker Discovery

scientific article published in 2009

MS-based plant metabolomic approaches for biomarker discovery

scientific article published on October 2009

Mass spectrometry-based metabolomics oriented by correlation analysis for wound-induced molecule discovery: identification of a novel jasmonate glucoside

scientific article published in January 2010

Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry

article

Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies

scientific article published on 28 December 2016

Metabolomics approach reveals disruption of metabolic pathways in the marine bivalve Mytilus galloprovincialis exposed to a WWTP effluent extract

scientific article published on 07 January 2020

Metabolomics reveals herbivore-induced metabolites of resistance and susceptibility in maize leaves and roots.

scientific article

Metabolomics: Application in Plant Sciences

article

Method development for pharmaceutics: Some solutions for tuning selectivity in reversed phase and hydrophilic interaction liquid chromatography

scientific article published on 28 January 2012

Methods for Doping Detection.

scientific article

Multi-way PLS for discrimination: Compact form equivalent to the tri-linear PLS2 procedure and its monotony convergence

Multifactorial Analysis of Environmental Metabolomic Data in Ecotoxicology: Wild Marine Mussel Exposed to WWTP Effluent as a Case Study

scientific article published on 29 June 2020

Multivariate data analysis of rapid LC-TOF/MS experiments from Arabidopsis thaliana stressed by wounding

article

Network principal component analysis: a versatile tool for the investigation of multigroup and multiblock datasets

scientific article published on 09 November 2020

New insights in pharmaceutical analysis

scientific article published in January 2012

Optimized liquid chromatography–mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance

article

Optimized selection of liquid chromatography conditions for wide range analysis of natural compounds.

scientific article

Phenotypic and molecular characterization of proliferating and differentiated GnRH-expressing GnV-3 cells.

scientific article published on 16 October 2010

Plant Metabolomics – Strategies for Biomarker Detection, Isolation, and Identification

article

Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identification.

scientific article published on 19 February 2016

Processing of NMR and MS metabolomics data using chemometrics methods: a global tool for fungi biotransformation reactions monitoring

scientific article published on 25 July 2019

Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesis

scientific article published on 27 December 2019

Profiling of steroid metabolites after transdermal and oral administration of testosterone by ultra-high pressure liquid chromatography coupled to quadrupole time-of-flight mass spectrometry

scientific article published on 21 June 2013

Protein pathway analysis to study development-dependent effects of acute and repeated trimethyltin (TMT) treatments in 3D rat brain cell cultures

scientific article published on 07 June 2019

Quantification of glucuronidated and sulfated steroids in human urine by ultra-high pressure liquid chromatography quadrupole time-of-flight mass spectrometry

scientific article published on 06 March 2011

Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology

scholarly article by Elyes Dahmane et al published April 2014 in Analytical and Bioanalytical Chemistry

Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening

scientific article published on 08 November 2018

Retention time prediction for dereplication of natural products (CxHyOz) in LC-MS metabolite profiling

scientific article published in December 2014

Rumen microbial communities influence metabolic phenotypes in lambs

scientific article

Standard machine learning algorithms applied to UPLC-TOF/MS metabolic fingerprinting for the discovery of wound biomarkers in Arabidopsis thaliana

scholarly article by Julien Boccard et al published November 2010 in Chemometrics and Intelligent Laboratory Systems

Standardized LC×LC-ELSD Fractionation Procedure for the Identification of Minor Bioactives via the Enzymatic Screening of Natural Extracts

scientific article

Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

scientific article

Steroid profile analysis by LC-HRMS in human seminal fluid

scientific article published on 09 December 2019

Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men.

scientific article published on 16 March 2018

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

scientific article published on 21 February 2017

Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells

scientific article

Steroidomics for highlighting novel serum biomarkers of testosterone doping

scientific article published on 10 June 2019

Structured plant metabolomics for the simultaneous exploration of multiple factors

scientific article

Supercritical fluid chromatography-mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditions

scientific article published on 12 December 2019

Synergy at the ' Ecole de Pharmacie Genève-Lausanne ': Methodology Developments for the Treatment of Complex Metabolomic Datasets with Data Mining

article published in 2005

Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry

scientific article published on 3 September 2013

Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry

scientific article published on 14 September 2015

Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom

scientific article published on 25 January 2017

Toward a better understanding of chronic kidney disease with complementary chromatographic methods hyphenated with mass spectrometry for improved polar metabolome coverage

scientific article published on 26 March 2019

UHPLC-HRMS Analysis for Steroid Profiling in Serum (Steroidomics)

scientific article published on 01 January 2018

UPLC-TOF-MS for plant metabolomics: a sequential approach for wound marker analysis in Arabidopsis thaliana

scientific article

Ultra-high performance supercritical fluid chromatography coupled with quadrupole-time-of-flight mass spectrometry as a performing tool for bioactive analysis.

scientific article published on 24 April 2016

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry.

scientific article published on 25 October 2017

Untargeted profiling of urinary steroid metabolites after testosterone ingestion: opening new perspectives for antidoping testing

scientific article published in January 2014

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