List of works - Ulrich Eckhard

A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

scientific article published on 28 May 2018

Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14.

scientific article published on 22 February 2016

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.

scientific article published on 22 September 2015

Biochemical characterization of the catalytic domains of three different Clostridial collagenases.

scientific article published in January 2009

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

scientific article published on 20 June 2018

Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide libraries

scientific article

Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum

scientific article published on 24 April 2008

Crystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1

scientific article

De novo design of immunoglobulin-like domains

scientific article published in 2022

Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2).

scientific article published on 25 July 2016

Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella

scientific article published on 12 September 2017

Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity

scientific article

LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification

scientific article published on 24 November 2014

Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase

article

Polycystic kidney disease-like domains of clostridial collagenases and their role in collagen recruitment ⬇️

scientific article published on August 28, 2011

Positional proteomics in the era of the human proteome project on the doorstep of precision medicine

scientific article

Protein Termini and Their Modifications Revealed by Positional Proteomics

scientific article

Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification.

scientific article published on 21 December 2017

Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen

scientific article

Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T

scientific article

Structure and Characterization of Phosphoglucomutase 5 from Atlantic and Baltic Herring-An Inactive Enzyme with Intact Substrate Binding

scientific article published on 03 December 2020

Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysis

scientific article

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

scientific article published on 27 July 2016

TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation.

scientific article published on 28 March 2018

TAILS N-terminomic and proteomic datasets of healthy human dental pulp

scientific article published on 16 October 2015

TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage

scientific article

The Human Dental Pulp Proteome and N-Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues

scientific article published on 10 August 2015

The Human Odontoblast Cell Layer and Dental Pulp Proteomes and N-Terminomes

scientific article published in October 2017

List of works by Ulrich Eckhard

A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function

Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14.

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.

Biochemical characterization of the catalytic domains of three different Clostridial collagenases.

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide libraries

Crystallization and preliminary X-ray characterization of the catalytic domain of collagenase G from Clostridium histolyticum

Crystallographically Mapped Ligand Binding Differs in High and Low IgE Binding Isoforms of Birch Pollen Allergen Bet v 1

De novo design of immunoglobulin-like domains

Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2).

Discovery of a proteolytic flagellin family in diverse bacterial phyla that assembles enzymatically active flagella

Family-wide characterization of matrix metalloproteinases from Arabidopsis thaliana reveals their distinct proteolytic activity and cleavage site specificity

LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification

Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase

Polycystic kidney disease-like domains of clostridial collagenases and their role in collagen recruitment ⬇️

Positional proteomics in the era of the human proteome project on the doorstep of precision medicine

Protein Termini and Their Modifications Revealed by Positional Proteomics

Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification.

Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen

Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T

Structure and Characterization of Phosphoglucomutase 5 from Atlantic and Baltic Herring-An Inactive Enzyme with Intact Substrate Binding

Structure of collagenase G reveals a chew-and-digest mechanism of bacterial collagenolysis

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation.

TAILS N-terminomic and proteomic datasets of healthy human dental pulp

TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage

The Human Dental Pulp Proteome and N-Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues

The Human Odontoblast Cell Layer and Dental Pulp Proteomes and N-Terminomes