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List of works by Giorgio Inghirami

ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma

scientific article published in 2012

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

scientific article published on 27 September 2005

Advances in understanding the pathogenesis of systemic anaplastic large cell lymphomas

scientific article published on 06 January 2015

Amplification of Her-2/neu gene in Her-2/neu-overexpressing and -nonexpressing breast carcinomas and their synchronous benign, premalignant, and metastatic lesions detected by FISH in archival material

scientific article

Anaplastic large cell lymphoma: one or more entities among T-cell lymphoma?

scientific article published on December 2009

Anaplastic large-cell lymphoma ⬇️

scientific article published on August 1, 2011

Anaplastic lymphoma kinase in human cancer

scientific article published on 04 July 2011

Anaplastic lymphoma kinase inhibitors

scientific article published on 03 June 2015

Anaplastic lymphoma kinase: an oncogene for tumor vaccination

scientific article published on 30 March 2009

BRAF mutations in hairy-cell leukemia

scientific article

Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis: alternative drivers in anaplastic large cell lymphoma

scientific article published on July 2013

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

scientific article published on 13 October 2011

CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib

scientific article published on 5 December 2007

CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers

scientific article

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

scientific article published on 24 November 2015

Comparative analysis of cancer vaccine settings for the selection of an effective protocol in mice

scientific article published on 12 May 2013

Corrigendum: THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors

scientific article published on 20 February 2017

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

scientific article

Description of a novel Janus kinase 3 P132A mutation in acute megakaryoblastic leukemia and demonstration of previously reported Janus kinase 3 mutations in normal subjects

scientific article published on 23 May 2011

Differential Amplification and Overexpression of HER-2/neu, p53, MIB1, and Estrogen Receptor/Progesterone Receptor Among Medullary Carcinoma, Atypical Medullary Carcinoma, and High-Grade Invasive Ductal Carcinoma of Breast ⬇️

scientific article published on November 1, 2003

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

scientific article

Genetic alterations in systemic nodal and extranodal non‐cutaneous lymphomas derived from mature T cells and natural killer cells ⬇️

scientific article published on June 26, 2012

Genetics of follicular lymphoma transformation

scientific article

Human rgr: transforming activity and alteration in T-cell malignancies

scientific article

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

scientific article

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

scientific article

In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation

scientific article

Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells

scientific article

JAK-STAT in lymphoproliferative disorders

scientific article published on 11 August 2015

Lenalidomide plus R-CHOP21 in elderly patients with untreated diffuse large B-cell lymphoma: results of the REAL07 open-label, multicentre, phase 2 trial

scientific article

Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma

scientific article published on 16 August 2013

MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

scientific article published on 25 June 2013

Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications

scientific article published in September 2014

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

scientific article published on 5 November 2013

NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells

scientific article published on 3 November 2009

New and old functions of STAT3: a pivotal target for individualized treatment of cancer

scientific article

Oncogenic kinase fusions: an evolving arena with innovative clinical opportunities

scientific article

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas

scientific article

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

scientific article published on 4 September 2013

PRDM1/BLIMP1: a tumor suppressor gene in B and T cell lymphomas

scientific article published on 07 October 2014

Pathobiology of anaplastic large cell lymphoma

scientific article published on January 2010

Patient-derived tumor xenografts of lymphoproliferative disorders: are they surrogates for the human disease?

scientific article

Peripheral T-cell and NK cell lymphoproliferative disorders: cell of origin, clinical and pathological implications

scientific article

Phase III randomized trial of patient-specific vaccination for previously untreated patients with follicular lymphoma in first complete remission: protocol summary and interim report

scientific article published on June 2005

Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma

scientific article published on 26 May 2016

Retinoic acid/alpha-interferon combination inhibits growth and promotes apoptosis in mantle cell lymphoma through Akt-dependent modulation of critical targets

scientific article published on 6 February 2012

S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase

scientific article published on April 2002

STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma

scientific article published on 23 August 2013

STAT3: a multifaceted oncogene

scholarly article

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

scientific article

THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors

scientific article published on 30 January 2017

The Influence of Tissue Ischemia Time on RNA Integrity and Patient-Derived Xenografts (PDX) Engraftment Rate in a Non-Small Cell Lung Cancer (NSCLC) Biobank

scientific article published on 5 January 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

scientific article published on April 2016

The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.

scientific article

The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation

scientific article

The anaplastic lymphoma kinase in the pathogenesis of cancer

scientific article published on January 2008

The anaplastic lymphoma kinase is an effective oncoantigen for lymphoma vaccination

scientific article

The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development

scientific article

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL.

scientific article

The heterogeneous landscape of ALK negative ALCL.

scientific article

Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes

scientific article published on 25 October 2016

Tim-3+ T-bet+ tumor-specific Th1 cells colocalize with and inhibit development and growth of murine neoplasms.

scientific article published on February 2005

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase

scientific article

p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling

scientific journal article

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