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List of works by Maaike van den Born

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal

scientific article

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia

scientific article published on 27 January 2006

Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition

scientific article

Crypt stem cells as the cells-of-origin of intestinal cancer

scientific article

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

scientific article

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand

scientific journal article

Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

scientific article published on 23 September 2012

Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research

scientific article published on 05 October 2016

Identification of stem cells in small intestine and colon by marker gene Lgr5

scientific article (publication date: 25 October 2007)

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes ⬇️

scientific article published on February 4, 2011

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

scientific article

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

scientific article

Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia

scientific article published on 28 May 2015

Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon

scientific article published on 29 August 2016

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters

scientific article published on 27 January 2016

SOX9 is required for the differentiation of paneth cells in the intestinal epithelium

scientific journal article

The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis

scientific article published in 2011

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

scientific article

The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium

scientific journal article

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

scientific journal article

Wnt signalling induces maturation of Paneth cells in intestinal crypts

scientific journal article

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