List of works by Itay Tirosh

142 Genetic and Nongenetic Determinants of Cellular Architecture in IDH1-Mutant Oligodendrogliomas and Astrocytomas Using Single-Cell Transcriptome Analysis

scientific article published on August 2016

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks ⬇️

scientific article published on 16 July 2015

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.

scientific article

A genetic signature of interspecies variations in gene expression

scientific article published on 18 June 2006

A single-cell landscape of high-grade serous ovarian cancer

scientific article published on 22 June 2020

A single-cell survey of the small intestinal epithelium

scientific article published on 8 November 2017

A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

scientific article published on 22 February 2021

A yeast hybrid provides insight into the evolution of gene expression regulation.

scientific article published in May 2009

ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

scientific article published on 18 July 2019

Autocorrelation analysis reveals widespread spatial biases in microarray experiments

scientific article

CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome

scientific article

Challenges and emerging directions in single-cell analysis

scientific article published on 8 May 2017

Chromatin mediation of a transcriptional memory effect in yeast

scientific article published on 5 March 2015

Chromatin regulators as capacitors of interspecies variations in gene expression

scientific article

Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma

article

Comparative analysis indicates regulatory neofunctionalization of yeast duplicates

scientific article published in January 2007

Comparative biology: beyond sequence analysis

scientific article published on 10 August 2007

Computational analysis of nucleosome positioning

scientific article published in January 2012

Computational verification of protein-protein interactions by orthologous co-expression

scientific article

Correction: Epigenetically-Inherited Centromere and Neocentromere DNA Replicates Earliest in S-Phase.

scientific article published on 28 April 2011

Correction: Epigenetically-Inherited Centromere and Neocentromere DNA Replicates Earliest in S-Phase.

scientific article

Corrigendum: The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

scientific article published in September 2017

Coupled evolution of transcription and mRNA degradation

scientific article

DIPG-03. EXCITATORY SYNAPSES BETWEEN PRESYNAPTIC NEURONS AND POSTSYNAPTIC GLIOMA CELLS PROMOTE DIPG PROGRESSION

scientific article published on 22 June 2018

DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES.

scientific article

Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis

scientific article published on 10 May 2021

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

scientific article published on March 2017

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.

scientific article published in April 2018

Dissecting human gliomas by single-cell RNA sequencing

scientific article published on 7 July 2017

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

scientific article published on April 2016

Divergence of nucleosome positioning between two closely related yeast species: genetic basis and functional consequences

scientific article

Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase

scientific article

Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map.

scientific article

Evolution of gene sequence and gene expression are not correlated in yeast.

scientific article

Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns

scientific article

Expression noise and acetylation profiles distinguish HDAC functions

scientific article

Extensive divergence of yeast stress responses through transitions between induced and constitutive activation

scientific article

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

scientific article published on September 2016

HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS.

scientific article published on 30 May 2016

High-throughput Phenotyping of Lung Cancer Somatic Mutations

scientific article published on 28 July 2016

High-throughput Phenotyping of Lung Cancer Somatic Mutations

scientific article published in December 2017

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

scientific article

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

scientific article

Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis

scientific article published on 06 November 2019

Inferring regulatory mechanisms from patterns of evolutionary divergence

scientific article

Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma

scientific article published on 01 September 2020

Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

scientific article published on 27 August 2020

Nasopharyngeal carcinoma joins the single-cell party

scientific article published on 25 August 2020

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

scientific article published on 19 December 2018

On the relation between promoter divergence and gene expression evolution

scientific article published on 15 January 2008

Opposite GC skews at the 5' and 3' ends of genes in unicellular fungi

scientific article

PBAN receptor: employment of anti-receptor antibodies for its characterization and for development of a microplate binding assay

scientific article published on 10 June 2009

PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA.

scientific article

Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

scientific article published on 30 October 2020

Promoter architecture and the evolvability of gene expression

scientific article published on 14 December 2009

Promoter nucleosome organization shapes the evolution of gene expression

scientific article

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells

scientific article published on 10 April 2014

STEM-22LARGE-SCALE SINGLE-CELL RNA-seq REVEALS A DEVELOPMENTAL CELLULAR HIERARCHY IN HUMAN OLIGODENDROGLIOMA.

scientific article

Single cell RNA-seq highlights a role for a partial EMT in head and neck cancer

scientific article published on 07 March 2018

Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges

scientific article published on 01 July 2019

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

scientific article

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

scientific article

Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells

scientific article

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

scientific article published on 2 November 2016

Single-cell sequencing and its applications in head and neck cancer

scientific article published on 02 November 2019

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

scientific article published on 01 November 2018

Tackling the Many Facets of Glioblastoma Heterogeneity

scientific article published on 01 March 2020

The Glioma Stem Cell Model in the Era of Single-Cell Genomics

scientific article published on 01 May 2020

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

scientific article

The pattern and evolution of yeast promoter bendability

scientific article published on 6 April 2007

Transcriptional priming of cytoplasmic post-transcriptional regulation

scientific article published on November 2011

Two strategies for gene regulation by promoter nucleosomes

scientific article published on 30 April 2008

Widespread promoter-mediated coordination of transcription and mRNA degradation

scientific article published on 13 December 2012

Widespread remodeling of mid-coding sequence nucleosomes by Isw1.

scientific article published on 10 May 2010

miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis

scientific article

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