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List of works by Beat Fierz

A Modular Ligation Strategy for Asymmetric Bivalent Nucleosomes Trimethylated at K36 and K27

scientific article published on 12 March 2019

A bi-terminal protein ligation strategy to probe chromatin structure during DNA damage.

scientific article published on 21 March 2018

A two-state activation mechanism controls the histone methyltransferase Suv39h1.

scientific article published on 25 January 2016

Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries

scientific article

BAF restricts cGAS on nuclear DNA to prevent innate immune activation

scientific article published on 01 August 2020

Chromatin as an expansive canvas for chemical biology

scientific article published on 17 April 2012

DNA binding by PHF1 prolongs PRC2 residence time on chromatin and thereby promotes H3K27 methylation.

scientific article published on 23 October 2017

De novo design of protein interactions with learned surface fingerprints

scientific article published on 26 April 2023

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

scientific article published on 07 March 2010

Dynamic Chromatin Regulation from a Single Molecule Perspective

scientific article

Dynamic chromatin technologies: from individual molecules to epigenomic regulation in cells

scientific article

Dynamics of unfolded polypeptide chains as model for the earliest steps in protein folding.

scientific article published in September 2003

End-to-end vs interior loop formation kinetics in unfolded polypeptide chains

scientific article published on 01 January 2007

Engineering chromatin states: chemical and synthetic biology approaches to investigate histone modification function.

scientific article published on 21 April 2014

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction

scientific article

Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes

scientific article published on 14 October 2013

Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2.

scientific article

Local conformational dynamics in alpha-helices measured by fast triplet transfer

scientific article

Loop formation in unfolded polypeptide chains on the picoseconds to microseconds time scale

scholarly article

Multivalency governs HP1α association dynamics with the silent chromatin state.

scientific article

On the unusual fluorescence properties of xanthone in water

scientific article published on 22 June 2006

Revealing chromatin organization in metaphase chromosomes

scientific article published on 04 March 2019

Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α.

scientific article published on 16 January 2018

Single-molecule dynamics and genome-wide transcriptomics reveal that NF-kB (p65)-DNA binding times can be decoupled from transcriptional activation

scientific article published on 17 January 2019

Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis

scientific article published on 26 November 2012

Structural mechanism of cGAS inhibition by the nucleosome

scientific article published on 10 September 2020

Sumoylated human histone H4 prevents chromatin compaction by inhibiting long-range internucleosomal interactions

scientific article

Synthetic chromatin approaches to probe the writing and erasing of histone modifications

scientific article published on 04 February 2014

Testing the diffusing boundary model for the helix-coil transition in peptides

scientific article published on 22 July 2013

Traceless Synthesis of Asymmetrically Modified Bivalent Nucleosomes.

scientific article published on 25 January 2016

Using triplet-triplet energy transfer to measure conformational dynamics in polypeptide chains.

scientific article published on January 2007

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