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List of works by Tania F. de Koning-Ward

A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4

scientific article published on 16 July 2019

A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice

scientific article published on 06 May 2020

A common protein export pathway in malaria parasites

scientific article published on 20 October 2010

A new rodent model to assess blood stage immunity to the Plasmodium falciparum antigen merozoite surface protein 119 reveals a protective role for invasion inhibitory antibodies ⬇️

scientific article

A newly discovered protein export machine in malaria parasites

scientific article

A subset of Plasmodium falciparum SERA genes are expressed and appear to play an important role in the erythrocytic cycle

scientific article (publication date: 6 December 2002)

Acquisition of invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein 1 in a transmigrant population requires multiple infections

scientific article

Acute Plasmodium berghei Mouse Infection Elicits Perturbed Erythropoiesis With Features That Overlap With Anemia of Chronic Disease

scientific article published on 16 April 2020

Advances in molecular genetic systems in malaria

scientific article published on June 2015

An aspartyl protease directs malaria effector proteins to the host cell

scientific article

An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes

scientific article

Analysis of stage specificity of promoters in Plasmodium berghei using luciferase as a reporter.

scientific article published in May 1999

Antibodies against merozoite surface protein (MSP)-1(19) are a major component of the invasion-inhibitory response in individuals immune to malaria.

scientific article published in June 2001

Biosynthesis, localization, and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins (PTEX)

scientific article (publication date: 9 March 2012)

Blood-stage Plasmodium berghei infection generates a potent, specific CD8+ T-cell response despite residence largely in cells lacking MHC I processing machinery

scientific article published on 13 October 2011

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8alpha+ dendritic cells

scholarly article

CD1d-restricted NKT cells contribute to malarial splenomegaly and enhance parasite-specific antibody responses

scientific article published in September 2003

CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

scientific article published on 22 May 2014

Changes in the hemagglutinin gene of the neurovirulent influenza virus strain A/NWS/33.

scientific article published in January 1995

Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells.

scientific article

Characterisation of the urease-encoding gene complex of Yersinia enterocolitica.

scientific article published on July 1994

Complementation of Plasmodium berghei TRAP knockout parasites using human dihydrofolate reductase gene as a selectable marker.

scientific article published in March 2001

Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence

scientific article published on 17 February 2016

Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

scientific article published on 30 October 2017

Effect of bacterial invasion of macrophages on the outcome of assays to assess bacterium–macrophage interactions ⬇️

scientific article published on June 1, 1998

Evidence for a common role for the serine-type Plasmodium falciparum serine repeat antigen proteases: implications for vaccine and drug design

scientific article

Evidence that invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein-1 (MSP-1 19) can play a protective role against blood-stage Plasmodium falciparum infection in individuals in a malaria endemic area of Africa

scientific article published in July 2004

Host Porphobilinogen Deaminase Deficiency Confers Malaria Resistance in Plasmodium chabaudi but Not in Plasmodium berghei or Plasmodium falciparum During Intraerythrocytic Growth

scientific article published on 03 September 2020

Host cell remodelling in malaria parasites: a new pool of potential drug targets

scientific article published on 28 June 2016

Illuminating how malaria parasites export proteins into host erythrocytes

scientific article published on 12 February 2019

Immune-mediated mechanisms of parasite tissue sequestration during experimental cerebral malaria

scientific article published on 18 August 2010

Investigation of the Plasmodium falciparum food vacuole through inducible expression of the chloroquine resistance transporter (PfCRT)

scientific article

Keeping it simple: an easy method for manipulating the expression levels of malaria proteins

scientific article published on 30 October 2008

MSP1(19) miniproteins can serve as targets for invasion inhibitory antibodies in Plasmodium falciparum provided they contain the correct domains for cell surface trafficking

scientific article published in April 2008

Molecular Approaches to Malaria 2020

scientific article published on 16 November 2020

Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites

scientific article published on 20 April 2009

New insights into protein export in malaria parasites

scientific article published on 19 February 2010

PTEX is an essential nexus for protein export in malaria parasites

scientific article (publication date: 31 July 2014)

Plasmodium falciparum Nucleosomes Exhibit Reduced Stability and Lost Sequence Dependent Nucleosome Positioning

scientific article

Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

scientific article (publication date: 2 March 2017)

Plasmodium rhoptry proteins: why order is important

scientific article published on 06 April 2013

Plasmodium species: master renovators of their host cells

scientific article

Plasmodium translocon component EXP2 facilitates hepatocyte invasion

scientific article published on 06 November 2020

Protein export in Plasmodium parasites: from the endoplasmic reticulum to the vacuolar export machine

scientific article published on 17 February 2010

Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150

scientific article (publication date: November 2016)

Puromycin-N-acetyltransferase as a selectable marker for use in Plasmodium falciparum.

scientific article

Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds

scientific article published on 03 March 2020

Spotlight on proteins that aid malaria

scientific article published in Nature

Stable expression of green fluorescent protein in blood and mosquito stages of Plasmodium berghei

scientific article published in November 1998

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity

scientific article published on 15 January 2006

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

scientific article published on 01 May 2019

Tetracycline analogue-regulated transgene expression in Plasmodium falciparum blood stages using Toxoplasma gondii transactivators

scientific article

The Clp chaperones and proteases of the human malaria parasite Plasmodium falciparum

scientific article

The Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growth

scientific article (publication date: 15 February 2017)

The Plasmodium translocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth

scientific article (publication date: September 2013)

The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice

scientific article published on 8 September 2015

The cysteine protease dipeptidyl aminopeptidase 3 does not contribute to egress of Plasmodium falciparum from host red blood cells

scientific article published in PLoS ONE

The exported protein PbCP1 localises to cleft-like structures in the rodent malaria parasite Plasmodium berghei

scientific article (publication date: 2013)

The importance of human FcgammaRI in mediating protection to malaria

scientific article

The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host-parasite interface

scientific article published on 10 April 2018

The malaria parasite Plasmodium falciparum Sortilin is essential for merozoite formation and apical complex biogenesis

scientific article published on 26 March 2018

The role of osmiophilic bodies and Pfg377 expression in female gametocyte emergence and mosquito infectivity in the human malaria parasite Plasmodium falciparum

scientific article published on 11 December 2007

The selectable marker human dihydrofolate reductase enables sequential genetic manipulation of the Plasmodium berghei genome.

scientific article published in March 2000

Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon

scientific article

Truncation of Plasmodium berghei merozoite surface protein 8 does not affect in vivo blood-stage development

scientific article

Uncoupling the Threading and Unfoldase Actions of Plasmodium HSP101 Reveals Differences in Export between Soluble and Insoluble Proteins.

scientific article published on 4 June 2019

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