List of works - Suguru Yoshida

(Hexafluoroacetylacetonato)copper(I)-cycloalkyne complexes as protected cycloalkynes

scientific article published on 27 August 2020

1,8-bis(diphenylmethylium)naphthalenediyl dication as an organic oxidant: synthesis of benzidines via self-coupling of N,N-dialkylanilines

scientific article published on 01 November 2004

2-(2,2,2-Trifluoroethylidene)-1,3-dithiane monoxide as a trifluoromethylketene equivalent

scientific article published on 01 May 2009

2-Azidoacrylamides as compact platforms for efficient modular synthesis

scientific article published on 26 November 2020

3-Thioaryne Intermediates for the Synthesis of Diverse Thioarenes

scientific article published on 25 June 2019

A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach

scientific article published on 01 March 2019

A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates

scientific article published on 08 October 2015

A new organic two-electron oxidant: 9,10-diaryl-9,10-dihydroanthracene-9,10-bis(ylium)

scientific article published on 11 July 2013

A novel yellow fluorescent protein of recombinant apoPholasin with dehydrocoelenterazine

scientific article published on 26 March 2020

An Alternative Method for Generating Arynes from ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether

scientific article published on 01 June 2015

An efficient generation method and remarkable reactivities of 3-triflyloxybenzyne

scientific article published on 01 December 2014

Aryne Relay Chemistry en Route to Aminoarenes: Synthesis of 3-Aminoaryne Precursors via Regioselective Silylamination of 3-(Triflyloxy)arynes

scientific article published on 22 November 2016

Assembly of four modules onto a tetraazide platform by consecutive 1,2,3-triazole formations

scientific article published on 24 December 2020

C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase.

scientific article published on 18 June 2013

CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses

scientific article

Catalytic Functionalization of a Single C-F Bond of Trifluoromethylarenes Assisted by an ortho-Silyl Group Using a Trityl-Based All-in-One Reagent with Ytterbium Triflate Catalyst

scientific article published on 17 March 2020

Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity

scientific article published on 17 December 2019

Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects.

scientific article published on 21 September 2017

Concise Synthesis of v-Coelenterazines

scientific article published on 21 July 2015

Consecutive Aryne Generation Strategy for the Synthesis of 1,3-Diarylpyrazoles

scientific article published on 24 February 2020

Construction of Condensed Polycyclic Aromatic Frameworks through Intramolecular Cycloaddition Reactions Involving Arynes Bearing an Internal Alkyne Moiety

scientific article

Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions

scientific article published on 12 March 2018

Copper-catalyzed extended Pummerer reactions of ketene dithioacetal monoxides with alkynyl sulfides and ynamides with an accompanying oxygen rearrangement

scientific article published on 05 March 2013

Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy

scientific article

Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation

scientific article published in November 2013

Direct thioamination of arynes via reaction with sulfilimines and migratory N-arylation

scientific article published on 3 November 2015

Double click reaction: a novel method for chemical modification of biomolecules

scientific article published in April 2012

Enhanced clickability of doubly sterically-hindered aryl azides.

scientific article published on 5 September 2011

Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines

scientific article published on 27 December 2012

Facile assembly of three cycloalkyne-modules onto a platform compound bearing thiophene S,S-dioxide moiety and two azido groups

scientific article published on 26 March 2020

Further enhancement of the clickability of doubly sterically-hindered aryl azides by para-amino substitution

article

Generation of cycloheptynes and cyclooctynes via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates

scientific article published on 01 May 2015

HaloTag-based conjugation of proteins to barcoding-oligonucleotides

scientific article published on 01 January 2020

Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice

scientific article

Intermolecular reductive radical addition to 2-(2,2,2-trifluoroethylidene)-1,3-dithiane 1-oxide: experimental and theoretical studies

scientific article published on 22 November 2010

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

scientific article published on 03 December 2018

Luminescence enhancement of the catalytic 19 kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions.

scientific article published on 31 January 2014

Modular synthesis of bis- and tris-1,2,3-triazoles by permutable sequential azide-aryne and azide-alkyne cycloadditions

scientific article published on 01 October 2014

Naphthalene-1,8-diylbis(diphenylmethylium) as an organic two-electron oxidant: benzidine synthesis via oxidative self-coupling of N,N-dialkylanilines

scientific article published on 01 August 2006

Nucleophilic substitution reaction at the nitrogen of arylsulfonamides with phosphide anion

scientific article published on 14 November 2012

Palladium-catalyzed regio- and stereoselective hydrosilylation of electron-deficient alkynes

scientific article published on 23 February 2012

Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice.

scientific article published on 5 September 2017

Reaction of 2-(2,2,2-trifluoroethylidene)-1,3-dithiane 1-oxide with ketones under Pummerer conditions and its application to the synthesis of 3-trifluoromethyl-substituted five-membered heteroarenes

scientific article published in March 2010

Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia

scientific article

Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation

scientific article

Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates.

scientific article published on 18 September 2017

Selective inhibition of the kinase DYRK1A by targeting its folding process

scientific article (publication date: 22 April 2016)

Selective strain-promoted azide-alkyne cycloadditions through transient protection of bicyclo[6.1.0]nonynes with silver or gold

scientific article published on 27 July 2020

Sequential conjugation methods based on triazole formation and related reactions using azides

scientific article published on 01 February 2020

Single C-F Bond Cleavage of Trifluoromethylarenes with an ortho-Silyl Group

scientific article published on 17 June 2016

Single C-F Transformations of o-Hydrosilyl Benzotrifluorides with Trityl Compounds as All-in-One Reagents

scientific article published on 12 November 2020

Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells

scientific article published on 01 July 2018

Strain-promoted double-click reaction for chemical modification of azido-biomolecules

scientific article published on 26 July 2010

Substituted 5,6,11,12-tetradehydrodibenzo[a,e]cyclooctenes: syntheses, properties, and DFT studies of substituted Sondheimer-Wong diynes

scientific article published on 25 November 2014

Sulfoxide Synthesis from Sulfinate Esters under Pummerer-like Conditions

scientific article published on 26 March 2020

Sulfoxide synthesis from sulfinate esters under Pummerer-like conditions

scientific article published on 14 April 2020

Synthesis of 3-trifluoromethylbenzo[b]furans from phenols via direct ortho functionalization by extended Pummerer reaction

scientific article published on September 2010

Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates

scientific article published on 19 April 2019

Synthesis of Diverse Aromatic Ketones through C-F Cleavage of Trifluoromethyl Group

scientific article published on 21 April 2020

Synthesis of Diverse o-Arylthio-Substituted Diaryl Ethers by Direct Oxythiolation of Arynes with Diaryl Sulfoxides Involving Migratory O-Arylation

scientific article published on 06 October 2017

Synthesis of Diverse γ-Aryl-β-ketoesters via Aryne Intermediates Generated by C-C Bond Cleavage

scientific article published on 24 October 2019

Synthesis of Functionalized Benzopyran/Coumarin-Derived Aryne Precursors and Their Applications

scientific article published on 13 October 2020

Synthesis of Unsymmetrical Tertiary Phosphine Oxides via Sequential Substitution Reaction of Phosphonic Acid Dithioesters with Grignard Reagents

scientific article published on 11 July 2017

Synthesis of benzo[b]thiophenes by cyclization of arylketene dithioacetal monoxides under pummerer-like conditions

scientific article

Synthesis of benzyl sulfides via substitution reaction at the sulfur of phosphinic acid thioesters

scientific article published on 22 April 2020

Synthesis of bulky arylphosphanes by rhodium-catalyzed formal [2+2+2] cycloaddition reaction and their use as ligands

scientific article published in September 2008

Synthesis of multisubstituted cycloalkenes through carbomagnesiation of strained cycloalkynes

scientific article published on 28 May 2020

The mevalonate pathway regulates primitive streak formation via protein farnesylation

scientific article

Thiazolobenzyne: a versatile intermediate for multisubstituted benzothiazoles.

scientific article published on 25 August 2016

Three-Component Coupling of Triflyloxy-Substituted Benzocyclobutenones, Organolithium Reagents, and Arynophiles Promoted by Generation of Aryne via Carbon-Carbon Bond Cleavage

scientific article published on 23 February 2017

Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation

scientific article published on 14 June 2018

Transient protection of strained alkynes from click reaction via complexation with copper

scientific article published on 19 September 2014

Triazole formation of phosphinyl alkynes with azides through transient protection of phosphine by copper

scientific article published on 23 October 2020

List of works by Suguru Yoshida

(Hexafluoroacetylacetonato)copper(I)-cycloalkyne complexes as protected cycloalkynes

1,8-bis(diphenylmethylium)naphthalenediyl dication as an organic oxidant: synthesis of benzidines via self-coupling of N,N-dialkylanilines

2-(2,2,2-Trifluoroethylidene)-1,3-dithiane monoxide as a trifluoromethylketene equivalent

2-Azidoacrylamides as compact platforms for efficient modular synthesis

3-Thioaryne Intermediates for the Synthesis of Diverse Thioarenes

A facile preparation of functional cycloalkynes via an azide-to-cycloalkyne switching approach

A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates

A new organic two-electron oxidant: 9,10-diaryl-9,10-dihydroanthracene-9,10-bis(ylium)

A novel yellow fluorescent protein of recombinant apoPholasin with dehydrocoelenterazine

An Alternative Method for Generating Arynes from ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether

An efficient generation method and remarkable reactivities of 3-triflyloxybenzyne

Aryne Relay Chemistry en Route to Aminoarenes: Synthesis of 3-Aminoaryne Precursors via Regioselective Silylamination of 3-(Triflyloxy)arynes

Assembly of four modules onto a tetraazide platform by consecutive 1,2,3-triazole formations

C6-Deoxy coelenterazine analogues as an efficient substrate for glow luminescence reaction of nanoKAZ: the mutated catalytic 19 kDa component of Oplophorus luciferase.

CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses

Catalytic Functionalization of a Single C-F Bond of Trifluoromethylarenes Assisted by an ortho-Silyl Group Using a Trityl-Based All-in-One Reagent with Ytterbium Triflate Catalyst

Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity

Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects.

Concise Synthesis of v-Coelenterazines

Consecutive Aryne Generation Strategy for the Synthesis of 1,3-Diarylpyrazoles

Construction of Condensed Polycyclic Aromatic Frameworks through Intramolecular Cycloaddition Reactions Involving Arynes Bearing an Internal Alkyne Moiety

Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions

Copper-catalyzed extended Pummerer reactions of ketene dithioacetal monoxides with alkynyl sulfides and ynamides with an accompanying oxygen rearrangement

Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy

Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation

Direct thioamination of arynes via reaction with sulfilimines and migratory N-arylation

Double click reaction: a novel method for chemical modification of biomolecules

Enhanced clickability of doubly sterically-hindered aryl azides.

Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines

Facile assembly of three cycloalkyne-modules onto a platform compound bearing thiophene S,S-dioxide moiety and two azido groups

Further enhancement of the clickability of doubly sterically-hindered aryl azides by para-amino substitution

Generation of cycloheptynes and cyclooctynes via a sulfoxide-magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates

HaloTag-based conjugation of proteins to barcoding-oligonucleotides

Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice

Intermolecular reductive radical addition to 2-(2,2,2-trifluoroethylidene)-1,3-dithiane 1-oxide: experimental and theoretical studies

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

Luminescence enhancement of the catalytic 19 kDa protein (KAZ) of Oplophorus luciferase by three amino acid substitutions.

Modular synthesis of bis- and tris-1,2,3-triazoles by permutable sequential azide-aryne and azide-alkyne cycloadditions

Naphthalene-1,8-diylbis(diphenylmethylium) as an organic two-electron oxidant: benzidine synthesis via oxidative self-coupling of N,N-dialkylanilines

Nucleophilic substitution reaction at the nitrogen of arylsulfonamides with phosphide anion

Palladium-catalyzed regio- and stereoselective hydrosilylation of electron-deficient alkynes

Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice.

Reaction of 2-(2,2,2-trifluoroethylidene)-1,3-dithiane 1-oxide with ketones under Pummerer conditions and its application to the synthesis of 3-trifluoromethyl-substituted five-membered heteroarenes

Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia

Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation

Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates.

Selective inhibition of the kinase DYRK1A by targeting its folding process

Selective strain-promoted azide-alkyne cycloadditions through transient protection of bicyclo[6.1.0]nonynes with silver or gold

Sequential conjugation methods based on triazole formation and related reactions using azides

Single C-F Bond Cleavage of Trifluoromethylarenes with an ortho-Silyl Group

Single C-F Transformations of o-Hydrosilyl Benzotrifluorides with Trityl Compounds as All-in-One Reagents

Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells

Strain-promoted double-click reaction for chemical modification of azido-biomolecules

Substituted 5,6,11,12-tetradehydrodibenzo[a,e]cyclooctenes: syntheses, properties, and DFT studies of substituted Sondheimer-Wong diynes

Sulfoxide Synthesis from Sulfinate Esters under Pummerer-like Conditions

Sulfoxide synthesis from sulfinate esters under Pummerer-like conditions

Synthesis of 3-trifluoromethylbenzo[b]furans from phenols via direct ortho functionalization by extended Pummerer reaction

Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates

Synthesis of Diverse Aromatic Ketones through C-F Cleavage of Trifluoromethyl Group

Synthesis of Diverse o-Arylthio-Substituted Diaryl Ethers by Direct Oxythiolation of Arynes with Diaryl Sulfoxides Involving Migratory O-Arylation

Synthesis of Diverse γ-Aryl-β-ketoesters via Aryne Intermediates Generated by C-C Bond Cleavage

Synthesis of Functionalized Benzopyran/Coumarin-Derived Aryne Precursors and Their Applications

Synthesis of Unsymmetrical Tertiary Phosphine Oxides via Sequential Substitution Reaction of Phosphonic Acid Dithioesters with Grignard Reagents

Synthesis of benzo[b]thiophenes by cyclization of arylketene dithioacetal monoxides under pummerer-like conditions

Synthesis of benzyl sulfides via substitution reaction at the sulfur of phosphinic acid thioesters

Synthesis of bulky arylphosphanes by rhodium-catalyzed formal [2+2+2] cycloaddition reaction and their use as ligands

Synthesis of multisubstituted cycloalkenes through carbomagnesiation of strained cycloalkynes

The mevalonate pathway regulates primitive streak formation via protein farnesylation

Thiazolobenzyne: a versatile intermediate for multisubstituted benzothiazoles.

Three-Component Coupling of Triflyloxy-Substituted Benzocyclobutenones, Organolithium Reagents, and Arynophiles Promoted by Generation of Aryne via Carbon-Carbon Bond Cleavage

Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation

Transient protection of strained alkynes from click reaction via complexation with copper

Triazole formation of phosphinyl alkynes with azides through transient protection of phosphine by copper