Search filters

List of works by Daniel E. Weeks

A Comparison Study of Fixed and Mixed Effect Models for Gene Level Association Studies of Complex Traits

scientific article published on 4 July 2016

A Pipeline for Classifying Relationships Using Dense SNP/SNV Data and Putative Pedigree Information

scientific article

A comparison between microsatellite and single-nucleotide polymorphism markers with respect to two measures of information content

scientific article published on 30 December 2005

A comparison of two algorithms, MultiMap and gene mapping system, for automated construction of genetic linkage maps

scientific article published in January 1999

A comparison study of multivariate fixed models and Gene Association with Multiple Traits (GAMuT) for next-generation sequencing

scientific article published on 5 December 2016

A full genome scan for age-related maculopathy

scientific article published on 01 May 2000

A genome-wide association study of chronic otitis media with effusion and recurrent otitis media identifies a novel susceptibility locus on chromosome 2

scientific article

A genome-wide linkage scan identifies multiple chromosomal regions influencing serum lipid levels in the population on the Samoan islands

scientific article

A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study

scientific article

A genome-wide screen for susceptibility loci in ankylosing spondylitis

scientific article published on 01 April 1998

A hierarchical model for estimating significance levels of non-parametric linkage statistics for large pedigrees

article

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A high-resolution genetic linkage map of the pericentromeric region of the human X chromosome

scientific article published in March 1995

A juvenile-onset, progressive cataract locus on chromosome 3q21-q22 is associated with a missense mutation in the beaded filament structural protein-2

scientific article

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

scientific article published on 21 December 2015

A likelihood-based analysis of consistent linkage of a disease locus to two nonsyntenic marker loci: osteogenesis imperfecta versus COL1A1 and COL1A2.

scientific article published in September 1990

A linkage study across the T cell receptor A and T cell receptor B loci in families with rheumatoid arthritis

scientific article published on 01 October 1997

A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes

scientific article published on 20 April 2022

A missense variant in CREBRF is associated with taller stature in Samoans

scientific article published on 19 March 2020

A missense variant in CREBRF, rs373863828, is associated with fat-free mass, not fat mass in Samoan infants

scientific article published on 03 September 2020

A multilocus extension of the affected-pedigree-member method of linkage analysis ⬇️

scientific article published on April 1, 1992

A pooled case-control study of the apolipoprotein E (APOE) gene in age-related maculopathy

article

A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans

scientific article

A tale of two genotypes: consistency between two high-throughput genotyping centers

scientific article

A thrifty variant in CREBRF strongly influences body mass index in Samoans

scientific article

A whole genome linkage scan identifies multiple chromosomal regions influencing adiposity-related traits among Samoans.

scientific article published on 08 July 2008

ADCYAP1R1 and asthma in Puerto Rican children

scientific article published on 17 January 2013

ASTN1 and alcohol dependence: family-based association analysis in multiplex alcohol dependence families

scientific article published on 9 April 2012

Absence of a relationship between endometriosis and the N314D polymorphism of galactose-1-phosphate uridyl transferase in a UK population

scientific article published on 01 October 1999

Affected sib-pair analysis in endometriosis.

scientific article

Age-related maculopathy: a genomewide scan with continued evidence of susceptibility loci within the 1q31, 10q26, and 17q25 regions

scientific article

Age-related maculopathy: an expanded genome-wide scan with evidence of susceptibility loci within the 1q31 and 17q25 regions

scientific article published in November 2001

An X-linked version of the affected-pedigree-member method of linkage analysis

scientific article published on 01 January 1995

An epigenome-wide association study of total serum IgE in Hispanic children ⬇️

scientific article

An incremental algorithm for efficient multipoint linkage analysis

scientific article published in November 1995

Analysis of IMGSAC autism susceptibility loci: evidence for sex limited and parent of origin specific effects.

scientific article

Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkage

scientific article published on 30 December 2005

Analysis of complex oligogenic disease

scientific article published on 01 January 1997

Analysis of complex oligogenic disease

Applying novel genome-wide linkage strategies to search for loci influencing type 2 diabetes and adult height in American Samoa

scientific article published on April 2008

Assessment of chronic gamma radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia

scientific article published in October 1991

Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method

scientific article

Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population

scientific article published on 01 November 2001

Association tests using kernel-based measures of multi-locus genotype similarity between individuals

scientific article published on April 2010

Autosomal recessive juvenile parkinsonism maps to 6q25.2-q27 in four ethnic groups: detailed genetic mapping of the linked region

scientific article

Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores

scientific article published on 24 March 2017

C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes

scientific article

CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses

scientific article

Candidate gene analysis suggests a role for fatty acid biosynthesis and regulation of the complement system in the etiology of age-related maculopathy

scientific article published in June 2005

Candidate-gene screening and association analysis at the autism-susceptibility locus on chromosome 16p: evidence of association at GRIN2A and ABAT

scientific article

Casares' map function: no need for a 'corrected' Haldane's map function

scientific article published on 5 July 2008

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Clustering tooth surfaces into biologically informative caries outcomes.

scientific article

Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia

scientific article published on 15 November 2011

Comparative Study of Multipoint Methods for Genotype Error Detection

scientific article published on 01 January 2004

Comparison of allele-sharing statistics for general pedigrees

scientific article published in January 2000

Comparison of methods incorporating quantitative covariates into affected sib pair linkage analysis

scientific article published on 01 January 2006

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

scientific article published on 13 January 2012

Computer programs for multilocus haplotyping of general pedigrees.

scientific article published on June 1995

Consanguinity and relative-pair methods for linkage analysis

scientific article published in March 1998

Coordinated conditional simulation with SLINK and SUP of many markers linked or associated to a trait in large pedigrees

scientific article

DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study

scientific article published on 21 December 2018

Demographic, socioeconomic, and behavioral factors affecting patterns of tooth decay in the permanent dentition: principal components and factor analyses

scientific article published on 29 October 2012

Detecting heterogeneity with the affected-pedigree-member (APM) method

scientific article published in January 1993

Detection of tandem duplications and implications for linkage analysis.

scientific article published on June 1994

Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa/New Zealand

scientific article published on 2 May 2018

Discovery of cancer susceptibility genes: study designs, analytic approaches, and trends in technology.

scientific article

Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration susceptibility

scientific article

Distribution of genome-wide linkage disequilibrium based on microsatellite loci in the Samoan population

scientific article

Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families

scientific article published on June 2008

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

scientific article published on 24 August 2020

ECHS1 disease in two unrelated families of Samoan descent: Common variant - rare disorder

scientific article published on 28 October 2020

Effects of smoking and genotype on the PSR index of periodontal disease in adults aged 18-49.

scientific article

Efficient Identification of Null-Allele Single Nucleotide Polymorphism Markers

scientific article published on 28 November 2015

Efficient computation of lod scores: genotype elimination, genotype redefinition, and hybrid maximum likelihood algorithms

scientific article published in January 1989

Efficient simulation of P values for linkage analysis

scientific article published in February 2004

Efficient strategies for genomic searching using the affected-pedigree-member method of linkage analysis.

scientific article published in March 1994

Endophenotypes for Age-Related Macular Degeneration: Extending Our Reach into the Preclinical Stages of Disease

scientific article

Enhanced B Cell Alloantigen Presentation and Its Epigenetic Dysregulation in Liver Transplant Rejection

scientific article published on 11 December 2015

Enhanced genetic maps from family-based disease studies: population-specific comparisons

scientific article

Epigenome-wide association study links site-specific DNA methylation changes with cow's milk allergy

scientific article

Estimating prevalence, false-positive rate, and false-negative rate with use of repeated testing when true responses are unknown

scientific article published in November 2007

Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM).

scientific article

Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage

article

Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies

scientific article published on 12 September 2011

Exploring the Paradoxical Relationship of a Creb 3 Regulatory Factor Missense Variant With Body Mass Index and Diabetes Among Samoans: Protocol for the Soifua Manuia (Good Health) Observational Cohort Study

scientific article published on 23 July 2020

Familial aggregation of endometriosis in a large pedigree of rhesus macaques

scientific article published on February 2004

Further concerns about the genetics of pre-eclampsia.

scientific article published in October 1993

GWAS of dental caries patterns in the permanent dentition

scientific journal article

Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions

scientific article

Gene-dropping vs. empirical variance estimation for allele-sharing linkage statistics

scientific article published on December 2006

Generalized functional linear models for gene-based case-control association studies

scientific article

Genetic ME-a visualization application for merging and editing pedigrees for genetic studies

scientific article published on 16 June 2015

Genetic epidemiology of bilateral breast cancer: a linkage analysis using the affected-pedigree-member method.

scientific article published in January 1990

Genetic risk models: Influence of model size on risk estimates and precision

scientific article published on 15 February 2017

Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10.

scientific article published in November 1997

Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection.

scientific article

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

scientific article (2010)

Genetic-based prediction of disease traits: prediction is very difficult, especially about the future

scientific article

Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration

scientific article published on 15 January 2018

Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth

scientific article

Genome-wide association scan for childhood caries implicates novel genes

scientific journal article

Genome-wide association scan of dental caries in the permanent dentition

scientific article

Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels

scientific article published on 05 August 2020

Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children

scientific article

Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy

scientific article published in March 2018

Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years

scientific article published on 19 February 2014

Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries

scientific article

Genome-wide scan for adiposity-related phenotypes in adults from American Samoa.

scientific article published on 10 July 2007

Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26.

scientific article

Heritable patterns of tooth decay in the permanent dentition: principal components and factor analyses

scientific article

Human leptin locus (LEP) alleles and BMI in Samoans

scientific article published on 01 June 2002

INSIG2 variants, dietary patterns and metabolic risk in Samoa ⬇️

scientific article published on September 12, 2012

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

scientific article published on 15 September 2013

Identification of epidermal growth factor receptor (EGFR) genetic variants that modify risk for head and neck squamous cell carcinoma

scientific article

Improved programs for the affected-pedigree-member method of linkage analysis

scientific article published in January 1994

Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis

scientific article published on 01 November 1996

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Interleukin 10 polymorphisms in ankylosing spondylitis

article

Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers

scientific article

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1.

scientific article published in August 2017

Linear mixed models for association analysis of quantitative traits with next-generation sequencing data

Linkage analysis of adult height with parent-of-origin effects in the Framingham Heart Study

scientific article published on 31 December 2003

Linkage and association studies of the relationship between endometriosis and genes encoding the detoxification enzymes GSTM1, GSTT1 and CYP1A1.

scientific article published in November 2001

Linkage mapping of dopa–responsive dystonia (DRD) to chromosome 14q

scientific article published on 01 December 1993

Linkage methods for identifying genetic risk factors.

scientific article published on January 1990

Magnetic resonance imaging to assess familial risk in relatives of women with endometriosis

scientific article published on 01 October 1998

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

scientific article

Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis

scientific article published in January 1990

Mega2: data-handling for facilitating genetic linkage and association analyses

scientific article

Mega2: validated data-reformatting for linkage and association analyses

scientific article

Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis

scientific article

Meta-analysis of genome scans of age-related macular degeneration

scientific article published on 29 June 2005

Meta-analysis of quantitative pleiotropic traits for next-generation sequencing with multivariate functional linear models

scientific article published on 21 December 2016

Mitochondrial neurogastrointestinal encephalomyopathy syndrome maps to chromosome 22q13.32-qter.

scientific article

Molecular genetic analysis of Lubag.

scientific article published in January 1998

Molecular genetic investigations of autism

scientific article published in October 1998

Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees

scientific article published in January 2001

Multipoint mapping under genetic interference

scientific article published on 01 March 1993

Mutational mechanisms for generating microsatellite allele-frequency distributions: an analysis of 4,558 markers

scientific article published in May 1998

NOD2 gene polymorphism rs2066844 associates with need for combined liver-intestine transplantation in children with short-gut syndrome

scientific article published on 19 October 2010

Newton Morton's influence on genetics: the Morton number

scientific article published in January 2001

No "bias" toward the null hypothesis in most conventional multipoint nonparametric linkage analyses

scientific article published on October 2004

No convincing evidence of linkage for restless legs syndrome on chromosome 9p.

scientific article published on April 2005

Nonparametric simulation based linkage statistics for general pedigrees

scientific article published on 01 January 1997

Novel caries loci in children and adults implicated by genome-wide analysis of families.

scientific article published in June 2018

Ordered genotypes: an extended ITO method and a general formula for genetic covariance

scientific article

Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12

scientific article

Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions

scientific article published on 3 September 2009

Parallel computation of genetic likelihoods using CRI-MAP, PVM, and a network of distributed workstations

scientific article published in March 1995

PedCheck: A Program for Identification of Genotype Incompatibilities in Linkage Analysis ⬇️

scientific article published on July 1, 1998

Pedigree Selection and Information Content

scientific article published in August 2001

Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis

article

Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus

scientific article published on 15 July 2015

Preliminary ranking procedures for multilocus ordering

scientific article published in November 1987

Preliminary ranking procedures for multilocus ordering based on radiation hybrid data.

scientific article

Prevalence of adiposity and associated cardiometabolic risk factors in the Samoan genome-wide association study

scientific article

Programs for pedigree analysis: Mendel, Fisher, and dGene

article

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

scientific article

Rare-Variant Kernel Machine Test for Longitudinal Data from Population and Family Samples

scientific article

Re: "Widespread prevalence of a CREBRF variant among Māori and Pacific children is associated with weight and height in early childhood"

scientific article published on 6 March 2018

Relationship uncertainty linkage statistics (RULS): affected relative pair statistics that model relationship uncertainty

scientific article published on 01 May 2008

Replication of a genome-wide association study of birth weight in preterm neonates

scientific article published on 31 August 2011

Reply to Dr. Carothers: Support intervals for genetic risks

Report of a workshop on genetic linkage studies in schizophrenia

scientific article published in January 1990

Robust score statistics for QTL linkage analysis

scientific article published on 21 February 2008

Role of African ancestry and gene-environment interactions in predicting preterm birth

scientific article published on November 2011

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families. The International Molecular Genetic Study of Autism Consortium

scientific article published in October 1999

Seven new loci associated with age-related macular degeneration

scientific article

Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13–15

article

Similarity of DNA fingerprints due to chance and relatedness

scientific article published on 01 January 1993

Spinning convincing stories for both true and false association signals

scientific article published on 18 January 2019

Statistics for X-chromosome associations

article published in 2018

Statistics for nonparametric linkage analysis of X-linked traits in general pedigrees

scientific article

Stratified randomization controls better for batch effects in 450K methylation analysis: a cautionary tale

scientific article

Suggestive linkage detected for blood pressure related traits on 2q and 22q in the population on the Samoan islands

scientific article

Susceptibility genes for age-related maculopathy on chromosome 10q26

scientific article (2005)

Susceptibility loci for adiposity phenotypes on 8p, 9p, and 16q in American Samoa and Samoa

scientific article

The Khatri Sikh Diabetes Study (SDS): study design, methodology, sample collection, and initial results

scientific article published in February 2006

The Mega2R package: R tools for accessing and processing genetic data in common formats

The elusive goal of pedigree weights

scientific article published on January 2007

The gene for hereditary progressive dystonia with marked diurnal fluctuation maps to chromosome 14q

article

The genetic epidemiology of spontaneous endometriosis in the rhesus monkey

scientific article

The impact of genotype calling errors on family-based studies

scientific article published on 22 June 2016

Toward developing a genome-wide microsatellite marker set for linkage analysis in the rhesus macaque (Macaca mulatta): Identification of 76 polymorphic markers

scientific article published on 01 August 2001

Treatment of uninformative families in mean allele sharing tests for linkage

scientific article published on 12 May 2006

Trials, tribulations, and triumphs of the EM algorithm in pedigree analysis

scientific article published in January 1989

True and false positive peaks in genomewide scans: applications of length-biased sampling to linkage mapping.

scientific article

Two-dimensional linkage analyses of rheumatoid arthritis

scientific article

Type 2 Diabetes and Three Calpain-10 Gene Polymorphisms in Samoans: No Evidence of Association ⬇️

scientific article published on November 5, 2001

Ulcerative colitis is more strongly linked to chromosome 12 than Crohn's disease

scientific article published in August 2001

Use of MRI in genetic studies of endometriosis

Use of MRI in genetic studies of endometriosis

scientific article published on 01 August 1997

Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people

scientific article

Y chromosome mosaicism is associated with age-related macular degeneration

scientific article published on 29 August 2018

dbVOR: a database system for importing pedigree, phenotype and genotype data and exporting selected subsets

scientific article

…and linguistic diversity

scientific article published in Nature

Paulina is supported by:

About Paulina

Help