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List of works by Aileen King

A role for islet somatostatin in mediating sympathetic regulation of glucagon secretion

scientific article

ALK5 inhibition maintains islet endothelial cell survival but does not enhance islet graft revascularisation or function

scientific article published on 27 November 2014

Activin receptor-like kinase 5 inhibition reverses impairment of endothelial cell viability by endogenous islet mesenchymal stromal cells

scientific article published in March 2013

Animal models for diabetes: Understanding the pathogenesis and finding new treatments

scientific article published on 30 September 2015

Annexin A1 Is a Key Modulator of Mesenchymal Stromal Cell-Mediated Improvements in Islet Function

scientific article published on 15 October 2015

Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells.

scientific article published on January 2007

Assembly of bioactive multilayered nanocoatings on pancreatic islet cells: incorporation of α1-antitrypsin into the coatings

scientific article

Assessing Islet Transplantation Outcome in Mice

scientific article published on 01 January 2020

Characterization of the Effects of Mesenchymal Stromal Cells on Mouse and Human Islet Function

scientific article published on 08 May 2019

Co-transplantation of islets with mesenchymal stem cells in microcapsules demonstrates graft outcome can be improved in an isolated-graft model of islet transplantation in mice

scientific article published in February 2013

Co-transplantation of mesenchymal stem cells maintains islet organisation and morphology in mice

scientific article published on 26 January 2011

Composite Mesenchymal Stromal Cell Islets: Implications for Transplantation via the Clinically Preferred Intraportal Route.

scientific article published on 19 March 2018

Diabetes in Rats Is Cured by Islet Transplantation…But Only During Daytime

scientific article published on 5 August 2016

Effect of hyperglycaemia on muscarinic M3 receptor expression and secretory sensitivity to cholinergic receptor activation in islets.

scientific article published on 06 May 2014

Elevated levels of renal and circulating Nop-7-associated 2 (NSA2) in rat and mouse models of diabetes, in mesangial cells in vitro and in patients with diabetic nephropathy

scientific article published on 18 November 2011

Engraftment and growth of transplanted pancreatic islets.

scientific article

Imatinib prevents beta cell death in vitro but does not improve islet transplantation outcome.

scientific article published on 8 March 2016

Immunoisolation of Islets in High Guluronic Acid Barium-Alginate Microcapsules Does Not Improve Graft Outcome at the Subcutaneous Site

scientific article published on 28 February 2012

Impaired Nociception in the Diabetic Ins2+/Akita Mouse

scientific article published on 06 June 2018

In vivo laboratory practicals in research-led teaching: An example using glucose tolerance tests in lean and obese mice

scientific article published on 27 July 2011

Islet alpha cell number is maintained in microencapsulated islet transplantation

scientific article

Islet neuropeptide Y receptors are functionally conserved and novel targets for the preservation of beta-cell mass

scientific article

Islet transplantation outcomes in mice are better with fresh islets and exendin-4 treatment

scientific article published on 23 August 2005

Kisspeptin stimulation of insulin secretion: mechanisms of action in mouse islets and rats.

scientific article published on 17 February 2009

Maintenance of islet morphology is beneficial for transplantation outcome in diabetic mice.

scientific article

Mesenchymal stromal cell secretory factors induce sustained improvements in islet function pre- and post-transplantation

scientific article published on 27 October 2018

Mesenchymal stromal cells improve human islet function through released products and extracellular matrix

scientific article published on 3 November 2017

Metabolic phenotyping guidelines: assessing glucose homeostasis in rodent models

scientific article

Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function

scientific article

Nano-scale encapsulation enhances allograft survival and function of islets transplanted in a mouse model of diabetes

scientific article published on 14 January 2012

No Differences in Efficacy Between Noncultured and Cultured Islets in Reducing Hyperglycemia in a Nonvascularized Islet Graft Model

scientific article published on 01 October 2006

Nop-7-associated 2 (NSA2), a candidate gene for diabetic nephropathy, is involved in the TGFβ1 pathway.

scientific article published on 7 December 2012

Normal relationship of beta- and non-beta-cells not needed for successful islet transplantation

scientific article

Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling

scientific article

Nupr1 deletion protects against glucose intolerance by increasing beta cell mass

scientific article published on 31 July 2013

Optimizing beta cell function through mesenchymal stromal cell-mediated mitochondria transfer

scientific article published on 08 January 2020

Pre-culturing islets with mesenchymal stromal cells using a direct contact configuration is beneficial for transplantation outcome in diabetic mice.

scientific article

Preculturing Islets With Adipose-Derived Mesenchymal Stromal Cells Is an Effective Strategy for Improving Transplantation Efficiency at the Clinically Preferred Intraportal Site.

scientific article published on 24 March 2014

Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK.

scientific article

Selective ablation of peptide YY cells in adult mice reveals their role in beta cell survival

scientific article published on 2 May 2012

Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function

scientific article

Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes

scientific article

The effect of capsule composition in the reversal of hyperglycemia in diabetic mice transplanted with microencapsulated allogeneic islets

scientific article published in January 2003

The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

scientific article

The role of capsule composition and biologic responses in the function of transplanted microencapsulated islets of Langerhans

scientific article

The use of animal models in diabetes research ⬇️

scientific article published on June 1, 2012

Transient beneficial effects of exendin-4 treatment on the function of microencapsulated mouse pancreatic islets

scientific article published on 01 January 2007

Validation of Current Good Manufacturing Practice Compliant Human Pluripotent Stem Cell-Derived Hepatocytes for Cell-Based Therapy

scientific article published on 19 November 2018

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