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List of works by Peter Caravan

1H chemical shift magnetic resonance imaging probes with high sensitivity for multiplex imaging

scientific article published in March 2012

207 Molecular MR-Imaging of myocardium using EP-3600, a collagen specific contrast agent: assessment of myocardial perfusion defects in a swine model

3D molecular MR imaging of liver fibrosis and response to rapamycin therapy in a bile duct ligation rat model

scientific article

68Ga-NODAGA-Indole: An Allysine-Reactive Positron Emission Tomography Probe for Molecular Imaging of Pulmonary Fibrogenesis

scientific article published on 27 March 2019

A Chelate-Free Nano-Platform for Incorporation of Diagnostic and Therapeutic Isotopes

scientific article published on 07 January 2020

A High Relaxivity Magnetic Resonance Imaging Contrast Agent Targeted to Serum Albumin

A Janus Chelator Enables Biochemically Responsive MRI Contrast with Exceptional Dynamic Range

scientific article published on 02 December 2016

A Manganese Alternative to Gadolinium for MRI Contrast

scientific article published on 20 November 2015

A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism

scientific article

A lysine walk to high relaxivity collagen-targeted MRI contrast agents

scientific article published on 10 December 2008

Activation and retention: a magnetic resonance probe for the detection of acute thrombosis

scientific article

Advanced MRI of Liver Fibrosis and Treatment Response in a Rat Model of Nonalcoholic Steatohepatitis

scientific article published on 28 April 2020

Albumin binding, relaxivity, and water exchange kinetics of the diastereoisomers of MS-325, a gadolinium(III)-based magnetic resonance angiography contrast agent

scientific article

An extreme water exchange rate: the europium(II) aqua ion

scholarly article by Peter Caravan & André E. Merbach published 1997 in Chemical Communications

Applications for Transition-Metal Chemistry in Contrast-Enhanced Magnetic Resonance Imaging

scientific article published on 05 May 2020

Bimodal MR-PET agent for quantitative pH imaging.

scientific article

Bimodal thrombus imaging: simultaneous PET/MR imaging with a fibrin-targeted dual PET/MR probe--feasibility study in rat model

scientific article

Biodistribution of gadolinium-based contrast agents, including gadolinium deposition

scientific article

Bioorthogonal Fluorophore Linked DFO-Technology Enabling Facile Chelator Quantification and Multimodal Imaging of Antibodies

scientific article published on 18 December 2015

CM-101: Type I Collagen-targeted MR Imaging Probe for Detection of Liver Fibrosis

scientific article

Cationic Lanthanide Complexes of N,N'-Bis(2-pyridylmethyl)ethylenediamine-N,N'-diacetic Acid (H(2)bped).

scientific article

Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

Collagen-Targeted MRI Contrast Agent for Molecular Imaging of Fibrosis

scientific article published on 01 January 2007

Collagen-targeted molecular imaging in diffuse liver diseases

scientific article published on 31 July 2020

Combined magnetic resonance elastography and collagen molecular magnetic resonance imaging accurately stage liver fibrosis in a rat model.

scientific article published on 7 November 2016

Contrast agents for MRI: 30+ years and where are we going?

scientific article

Determination of the hydration number of gadolinium(III) complexes by high-field pulsed 17O ENDOR spectroscopy

scientific article

Development of a bone-targeted pH-sensitive liposomal formulation containing doxorubicin: physicochemical characterization, cytotoxicity, and biodistribution evaluation in a mouse model of bone metastasis

scientific article published on 09 August 2016

Direct measurement of the Mn(II) hydration state in metal complexes and metalloproteins through 17O NMR line widths

scientific article

Discrete bimodal probes for thrombus imaging

scientific article

EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus

scientific article published on 8 April 2008

Effect of Chelate Type and Radioisotope on the Imaging Efficacy of 4 Fibrin-Specific PET Probes

scientific article

Effect of Peptide-Chelate Architecture on Metabolic Stability of Peptide-based MRI Contrast Agents

scientific article

Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III)

scientific article published on 01 October 1997

Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III).

scientific article

Enzyme-Activated Gd3+ Magnetic Resonance Imaging Contrast Agents with a Prominent Receptor-Induced Magnetization Enhancement

scientific article published in August 2001

Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma

scientific article

Evaluation of antitumor activity and cardiac toxicity of a bone-targeted ph-sensitive liposomal formulation in a bone metastasis tumor model in mice.

scientific article published on 23 March 2017

Evidence for weak protein binding of commercial extracellular gadolinium contrast agents

scientific article published in March 2010

Fibrin Specific Peptides Derived by Phage Display: Characterization of Peptides and Conjugates for Imaging ⬇️

scientific article published on February 9, 2012

Fibrin-targeted PET probes for the detection of thrombi

scientific article published on 30 January 2013

Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and is Measurable with Collagen-Targeted Molecular MRI

scientific article published on 01 July 2020

Gadofosveset-enhanced magnetic resonance imaging of human carotid atherosclerotic plaques: a proof-of-concept study

article

Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications

scientific article (publication date: 8 September 1999)

Gadolinium-Free Contrast Agents for Magnetic Resonance Imaging of the Central Nervous System

scientific article published on 12 February 2018

Gadolinium-based contrast agents in pediatric magnetic resonance imaging

scientific article published on 13 April 2017

Gadolinium-binding helix-turn-helix peptides: DNA-dependent MRI contrast agents

scientific article published in October 2003

Gd(DOTAla): a single amino acid Gd-complex as a modular tool for high relaxivity MR contrast agent development

scientific article

Gd(DOTAlaP): exploring the boundaries of fast water exchange in gadolinium-based magnetic resonance imaging contrast agents

scientific article

Gd3TCAS2: An Aquated Gd(3+)-Thiacalix[4]arene Sandwich Cluster with Extremely Slow Ligand Substitution Kinetics

scientific article published on 28 March 2016

Glucose-lowering properties of vanadium compounds: Comparison of coordination complexes with maltol or kojic acid as ligands ⬇️

scientific article published on November 1, 1997

Gut microbiota is critical for the induction of chemotherapy-induced pain.

scientific article published on 17 July 2017

Heteroditopic Binding of Magnetic Resonance Contrast Agents for Increased Relaxivity

Heteroditopic binding of magnetic resonance contrast agents for increased relaxivity

scientific article

Hexameric Mn(II) dendrimer as MRI contrast agent

scientific article

High relaxivity magnetic resonance imaging contrast agents. Part 1. Impact of single donor atom substitution on relaxivity of serum albumin-bound gadolinium complexes

scientific article

High sensitivity HPLC method for determination of the allysine concentration in tissue by use of a naphthol derivative

scientific article published on 26 August 2017

High-Frequency EPR and ENDOR Characterization of MRI Contrast Agents

High-field pulsed EPR and ENDOR of Gd3+ complexes in glassy solutions

High-relaxivity magnetic resonance imaging contrast agents. Part 2. Optimization of inner- and second-sphere relaxivity

scientific article

High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease.

scientific article

Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs

scientific article published on 20 October 2020

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress

scientific article published on 01 August 2018

Improving the reactivity of hydrazine-bearing MRI probes for in vivo imaging of lung fibrogenesis

scientific article published on 08 November 2019

In Memoriam: Seymour H. Koenig (1927-2018)

In vivo molecular imaging of thrombosis and thrombolysis using a fibrin-binding positron emission tomographic probe

scientific article

In vivo mri of the left coronary artery branching patterns in mice and the myocardial area-at-risk during coronary ligation: towards improved understanding of an important model

Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium- and manganese-based T1 contrast agents

scientific article

Interpretation of Activation Volumes for Water Exchange Reactions Revisited: AbInitioCalculations for Al3+, Ga3+, and In3+, and New Experimental Data

scientific article published in 1998

Intramolecular Hydrogen Bonding Restricts Gd-Aqua-Ligand Dynamics

Intramolecular Hydrogen Bonding Restricts Gd-Aqua-Ligand Dynamics.

scientific article

Is macrocycle a synonym for kinetic inertness in Gd(III) Complexes? Effect of coordinating and noncoordinating substituents on inertness and relaxivity of Gd(III) chelates with DO3A-like ligands

scientific article

Laser-assisted delivery of synergistic combination chemotherapy in in vivo skin

scientific article published on 14 February 2018

MR imaging probes: design and applications

scientific article

Macrocycle-Based Hydroxamate Ligands for Complexation and Immunoconjugation of 89Zirconium for Positron Emission Tomography (PET) Imaging

scientific article

Magnetic resonance labeling of stem cells: is positive tracking a plus or a minus?

scientific article published on September 2009

Manganese-Based Contrast Agents for Magnetic Resonance Imaging of Liver Tumors: Structure–Activity Relationships and Lead Candidate Evaluation

scientific article published on 25 September 2018

Metabolite profiling with HPLC-ICP-MS as a tool for in vivo characterization of imaging probes

scientific article published on 22 January 2018

Molecular MR imaging of fibrosis in a mouse model of pancreatic cancer.

scientific article published on 14 August 2017

Molecular MR imaging of liver fibrosis: a feasibility study using rat and mouse models

scientific article

Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents

scientific article published on April 2009

Molecular MRI of Thrombosis

scientific article

Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium

scientific article

Molecular MRI of acute necrosis with a novel dna-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium.

scientific article

Molecular MRI of collagen to diagnose and stage liver fibrosis

scientific article published on 06 July 2013

Molecular MRI of intracranial thrombus in a rat ischemic stroke model

scientific article

Molecular MRI of myocardial peroxidase activity in ischemic injury reveals a chemical milieu incompatible with stem cell survival

scientific article

Molecular MRI of the Cardiovascular System in the Post-NSF Era ⬇️

scientific article published on November 29, 2012

Molecular Magnetic Resonance Imaging Using a Redox-Active Iron Complex

scientific article published on 28 March 2019

Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine-Based Probe

scientific article

Molecular Magnetic Resonance Imaging of Lung Fibrogenesis with an Oxyamine-Based Probe

Molecular Probes for Imaging Fibrosis and Fibrogenesis

scientific article published on 21 November 2018

Molecular factors that determine Curie spin relaxation in dysprosium complexes

Molecular factors that determine Curie spin relaxation in dysprosium complexes† ⬇️

scientific article published on November 1, 2001

Molecular imaging of fibrin in a breast cancer xenograft mouse model.

scientific article published on October 2012

Molecular imaging of fibrosis: recent advances and future directions

scientific article published on 02 January 2019

Molecular imaging of oxidized collagen quantifies pulmonary and hepatic fibrogenesis

scientific article published on 2 June 2017

Molecular magnetic resonance imaging of myocardial perfusion with EP-3600, a collagen-specific contrast agent: initial feasibility study in a swine model

scientific article published on 23 March 2009

Molecular magnetic resonance imaging of pulmonary fibrosis in mice

scientific article published on December 2013

Monovalent and bivalent fibrin-specific MRI contrast agents for detection of thrombus

scientific article published in January 2008

Multilocus Binding Increases the Relaxivity of Protein-Bound MRI Contrast Agents

scientific article published on 01 October 2005

Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111In- and 68Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

scientific article published on 6 August 2015

Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats

scientific article

Noninvasive Biomarkers of Liver Fibrosis: Clinical Applications and Future Directions

scientific article

Noninvasive quantification of fibrosis in skeletal and cardiac muscle in mdx mice using EP3533 enhanced magnetic resonance imaging

Nuclear and Electronic Relaxation of Eu2+(aq): An Extremely Labile Aqua Ion1

scientific article published in 1999

On the philosophy of optimizing contrast agents. An analysis of 1H NMRD profiles and ESR lineshapes of the Gd(III)complex MS-325+HSA.

scientific article

Optimization of a Collagen-Targeted PET Probe for Molecular Imaging of Pulmonary Fibrosis.

scientific article published on 13 June 2017

Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy

article

Peptide optimization and conjugation strategies in the development of molecularly targeted magnetic resonance imaging contrast agents

scientific article published in January 2014

Peptide-based fibrin-targeting probes for thrombus imaging

scientific article published on 20 October 2017

Peroxidase Sensitive Amplifiable Probe for Molecular Magnetic Resonance Imaging of Pulmonary Inflammation

scientific article published on 22 August 2019

Postinfarction myocardial scarring in mice: molecular MR imaging with use of a collagen-targeting contrast agent.

scientific article

Potentiometric and relaxometric properties of a gadolinium-based MRI contrast agent for sensing tissue pH

scientific article

Potentiometric, Calorimetric, and Solution NMR Studies of a Tridentate Ligand Which has a Marked Preference for Formation of Bis(ligand) versus Mono(ligand) Lanthanide Complexes and Which Exhibits High Selectivity for Heavier Lanthanides

scientific article published in 1995

Primer on gadolinium chemistry.

scientific article

Probing the structure-relaxivity relationship of bis-hydrated Gd(DOTAla) derivatives

scientific article published on 18 February 2015

Probing the water coordination of protein-targeted MRI contrast agents by pulsed ENDOR spectroscopy

scientific article published in December 2005

Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet-induced mouse model of nonalcoholic steatohepatitis.

scientific article

Protein binding to lanthanide(III) complexes can reduce the water exchange rate at the lanthanide

scientific article

Protein-targeted gadolinium-based magnetic resonance imaging (MRI) contrast agents: design and mechanism of action

scientific article

Pulsed ENDOR Study of Water Coordination to Gd3+Complexes in Orientationally Disordered Systems

Pycup--a bifunctional, cage-like ligand for (64)Cu radiolabeling

scientific article

Radiation Dosimetry of the Fibrin-Binding Probe ⁶⁴Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats

scientific article published on 14 May 2015

Rational Ligand Design Enables pH Control over Aqueous Iron Magnetostructural Dynamics and Relaxometric Properties

scientific article published on 20 November 2020

Redox-activated manganese-based MR contrast agent

scientific article published on 19 March 2013

Revisiting dithiadiaza macrocyclic chelators for copper-64 PET imaging

scientific article published on 24 September 2020

Science to practice: how will myocardial inflammation be imaged with MR imaging?

scientific article published on August 2012

Selectivity among, and aggregation of, lanthanide ions

Selectivity of Potentially Hexadentate Amine Phenols for Ga3+and In3+in Aqueous Solution†,‡

Serum albumin targeted, pH-dependent magnetic resonance relaxation agents

scientific article

Species dependence on plasma protein binding and relaxivity of the gadolinium-based MRI contrast agent MS-325.

scientific article published in March 2006

Strategies for increasing the sensitivity of gadolinium based MRI contrast agents

scientific article

Strategies for the preparation of bifunctional gadolinium(III) chelators

scientific article published on August 2011

Structural, kinetic, and thermodynamic characterization of the interconverting isomers of MS-325, a gadolinium(III)-based magnetic resonance angiography contrast agent

scientific article

Structure - relaxivity relationships among targeted MR contrast agents

scientific article

Structure-redox-relaxivity relationships for redox responsive manganese-based magnetic resonance imaging probes

scientific article

Structure-relaxivity relationships of serum albumin targeted MRI probes based on a single amino acid Gd complex

scientific article

Synthesis and evaluation of a high relaxivity manganese(II)-based MRI contrast agent

scientific article

Synthesis and relaxometric studies of a dendrimer-based pH-responsive MRI contrast agent.

scientific article published on January 2008

T2 relaxation time is related to liver fibrosis severity.

scientific article

Targeted probes for cardiovascular MRI

scientific article

The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities.

scientific article

The biological fate of gadolinium-based MRI contrast agents: a call to action for bioinorganic chemists

scientific article published on 01 February 2019

The gadolinium(III)-water hydrogen distance in MRI contrast agents

scientific article

The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates

scientific article

The reactions of O(3P) with some carboxylic acids and esters

Thermodynamic stability and kinetic inertness of MS-325, a new blood pool agent for magnetic resonance imaging

scientific article published in April 2001

Thrombus imaging with fibrin-specific gadolinium-based MR contrast agent EP-2104R: results of a phase II clinical study of feasibility

scientific article published in November 2009

Tightening the Hydrophobic Belt: Effects of Backbone and Donor Group Variation on Podand Ligand Complexes of the Lanthanides

Tripodal Aminophenolate Ligand Complexes of Aluminum(III), Gallium(III), and Indium(III) in Water

scholarly article by Peter Caravan & Chris Orvig published January 1997 in Inorganic Chemistry

Type I Collagen-targeted Positron Emission Tomography Imaging in Idiopathic Pulmonary Fibrosis: First-in-Human Studies

scientific article published on 01 July 2019

Type I collagen-targeted PET probe for pulmonary fibrosis detection and staging in preclinical models.

scientific article published in April 2017

Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis

scientific article

W-Band17O Pulsed Electron Nuclear Double Resonance Study of Gadolinium Complexes with Water

Water exchange in lanthanide complexes for MRI applications. Lessons learned over the last 25 years

scientific article published on 26 June 2019

When are two waters worse than one? Doubling the hydration number of a Gd-DTPA derivative decreases relaxivity

scientific article

Whole brain mapping of water pools and molecular dynamics with rotating frame MR relaxation using gradient modulated low-power adiabatic pulses

scientific article

Yttrium-86 Is a Positron Emitting Surrogate of Gadolinium for Noninvasive Quantification of Whole-Body Distribution of Gadolinium-Based Contrast Agents

scientific article published on 04 December 2019

[Gd(CyPic3A)(H2O)2]-: a stable, bis(aquated) and high-relaxivity Gd(III) complex

scientific article published on August 2013

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