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List of works by Chiara Verpelli

Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system

scientific article

Anti-AMPA GluA3 antibodies in Frontotemporal dementia: a new molecular target.

scientific article published on 27 July 2017

Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma

scientific article

Antiangiogenic therapy for glioma

scientific article

Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles

scientific article published on 01 June 2020

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

scientific article published on 26 August 2012

Combination of temozolomide with immunocytokine F16-IL2 for the treatment of glioblastoma

scientific article

Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness.

scientific article published in September 2009

Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells

scientific article published on 07 October 2013

Dimerizable redox-sensitive triazine-based cationic lipids for in vitro gene delivery

scientific article published on March 2007

Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons

scientific article published in 2014

Expression of cocaine-evoked synaptic plasticity by GluN3A-containing NMDA receptors.

scientific article published on 31 October 2013

Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency

scientific article published on 17 July 2014

Glial degeneration with oxidative damage drives neuronal demise in MPSII disease

scientific article published on 11 August 2016

Homer1b/c clustering is impaired in Phelan-McDermid Syndrome iPSCs derived neurons

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

scientific article

Modelling Autistic Neurons with Induced Pluripotent Stem Cells

scientific article

Molecular and synaptic defects in intellectual disability syndromes ⬇️

scientific article published on October 13, 2011

Molecular basis for prospective pharmacological treatment strategies in intellectual disability syndromes

scientific article published on 19 July 2013

Mutations of the synapse genes and intellectual disability syndromes

scientific article published on 17 July 2013

Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice

scientific article

Phosphorylation of neuronal Lysine-Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2

scientific article

Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder

scientific article published on 14 February 2017

Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.

scientific article

Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD

scientific journal article

SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region

scientific article published on 29 July 2013

SOD1 stimulates lamellipodial protrusions in Neuro 2A cell lines

scientific article published on 09 August 2018

SULT4A1 modulates synaptic development and function by promoting the formation of PSD-95/NMDAR complex

scientific article published on 12 August 2020

Scaffold proteins at the postsynaptic density

scientific article published on January 2012

Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders

scientific article published on 06 July 2015

Spikar speaks to spines and nuclei

Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis

scientific journal article

Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage

scientific article published on December 2010

The GluR2 subunit inhibits proliferation by inactivating Src-MAPK signalling and induces apoptosis by means of caspase 3/6-dependent activation in glioma cells

scientific article

The X-Linked Intellectual Disability Protein IL1RAPL1 Regulates Dendrite Complexity.

scientific article published on 2 June 2017

The neuropeptide PACAP38 induces dendritic spine remodeling through ADAM10-N-cadherin signaling pathway

scientific article published on 10 February 2012

The postsynaptic density proteins Homer and Shank form a polymeric network structure

scientific article

eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures.

scientific article published on 21 March 2016

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