List of works - Rodney Samaco

A framework for the investigation of rare genetic disorders in neuropsychiatry

scientific article published on 23 September 2019

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

scientific article

Adult neural function requires MeCP2.

scientific article published on 2 June 2011

Complexities of Rett Syndrome and MeCP2: Figure 1 ⬇️

scientific article published on June 1, 2011

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

scientific article

Current Perspectives in Autism Spectrum Disorder: From Genes to Therapy

scientific article

Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress.

scientific article published on September 2008

Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes

scientific article published on 18 February 2007

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

scientific article

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

scientific article

Evaluating Two Common Strategies for Research Participant Recruitment Into Autism Studies: Observational Study

scientific article published on 24 September 2020

Expression of FoxP2 during zebrafish development and in the adult brain

scientific article

Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies

scientific article

Forniceal deep brain stimulation rescues hippocampal memory in Rett syndrome mice

scientific article published on October 2015

Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies

scientific article published in September 2017

Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen

scientific article published on 13 September 2021

Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome

scientific article

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

scientific article

Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.

scientific article

MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain.

scientific article published on 25 April 2002

Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders

scientific article (publication date: 15 March 2004)

Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome

scientific article published in February 2018

Preclinical research in Rett syndrome: setting the foundation for translational success.

scientific article

Rigor and Reproducibility in Rodent Behavioral Research.

scientific article published on 4 January 2018

X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain.

scientific article

miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis

scientific article

List of works by Rodney Samaco

A framework for the investigation of rare genetic disorders in neuropsychiatry

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

Adult neural function requires MeCP2.

Complexities of Rett Syndrome and MeCP2: Figure 1 ⬇️

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

Current Perspectives in Autism Spectrum Disorder: From Genes to Therapy

Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress.

Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.

Evaluating Two Common Strategies for Research Participant Recruitment Into Autism Studies: Observational Study

Expression of FoxP2 during zebrafish development and in the adult brain

Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies

Forniceal deep brain stimulation rescues hippocampal memory in Rett syndrome mice

Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies

Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen

Loss of MeCP2 Causes Urological Dysfunction and Contributes to Death by Kidney Failure in Mouse Models of Rett Syndrome

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.

MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain.

Multiple pathways regulate MeCP2 expression in normal brain development and exhibit defects in autism-spectrum disorders

Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome

Preclinical research in Rett syndrome: setting the foundation for translational success.

Rigor and Reproducibility in Rodent Behavioral Research.

X-Chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain.

miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis