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List of works by Carlos Garcia-Estrada

A Single Cluster of Coregulated Genes Encodes the Biosynthesis of the Mycotoxins Roquefortine C and Meleagrin in Penicillium chrysogenum

scientific article

A natural short pathway synthesizes roquefortine C but not meleagrin in three different Penicillium roqueforti strains.

scientific article

A novel active DNA topoisomerase I in Leishmania donovani.

scientific article published on 19 November 2002

Analysis of genetic elements regulating the methionine adenosyltransferase gene in Leishmania infantum

article

Axenic interspecies and intraclonal hybrid formation in Leishmania: Successful crossings between visceral and cutaneous strains

scientific article published on 09 February 2022

Biosynthesis of Astaxanthin as a Main Carotenoid in the Heterobasidiomycetous Yeast Xanthophyllomyces dendrorhous.

scientific article published on 30 July 2017

Biosynthetic gene clusters for relevant secondary metabolites produced by Penicillium roqueforti in blue cheeses

scientific article

Casein phosphopeptides and CaCl2 increase penicillin production and cause an increment in microbody/peroxisome proteins in Penicillium chrysogenum

scientific article

Casein phosphopeptides drastically increase the secretion of extracellular proteins in Aspergillus awamori. Proteomics studies reveal changes in the secretory pathway ⬇️

scientific article published on January 10, 2012

Catabolism of phenylacetic acid in Penicillium rubens. Proteome-wide analysis in response to the benzylpenicillin side chain precursor

scientific article published on 06 August 2018

Characterization of an autoinducer of penicillin biosynthesis in Penicillium chrysogenum.

scientific article

Characterization of the 5' region of the Leishmania infantum LORIEN/MAT2 gene cluster and role of LORIEN flanking regions in post-transcriptional regulation.

scientific article published on 28 March 2008

Cloning expression and characterization of methionine adenosyltransferase in Leishmania infantum promastigotes

scientific article published on 6 November 2001

Current status on prevention and treatment of canine leishmaniasis

scientific article published on 12 July 2016

DNA Topoisomerases of Leishmania Parasites; Druggable Targets for Drug Discovery

scientific article published on 01 January 2019

DNA topoisomerases in apicomplexan parasites: promising targets for drug discovery

scientific article published on 03 March 2010

Direct involvement of the CreA transcription factor in penicillin biosynthesis and expression of the pcbAB gene in Penicillium chrysogenum.

scientific article published on 13 May 2014

Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506).

scientific article

Effect of Sunflower and Marine Oils on Ruminal Microbiota, In vitro Fermentation and Digesta Fatty Acid Profile

scientific article published on 20 June 2017

Extraction and Analysis of Carotenes and Xanthophylls Produced by Xanthophyllomyces dendrorhous

scientific article published on 01 January 2018

Functional characterization of the polyketide synthase gene required for ochratoxin A biosynthesis in Penicillium verrucosum

scientific article published on 28 December 2012

Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania major

scientific article

Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum

scientific article

In vivo transport of the intermediates of the penicillin biosynthetic pathway in tailored strains of Penicillium chrysogenum

scientific article published on 22 May 2007

Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.

scientific article

Methods for the nanoencapsulation of β-carotene in the food sector

Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani.

scientific article

Molecular characterization of a fungal gene paralogue of the penicillin penDE gene of Penicillium chrysogenum

scientific article

Molecular characterization of the PR-toxin gene cluster in Penicillium roqueforti and Penicillium chrysogenum: cross talk of secondary metabolite pathways.

scientific article

Motifs in the C-terminal region of the Penicillium chrysogenum ACV synthetase are essential for valine epimerization and processivity of tripeptide formation

scientific article published on 27 August 2011

Mutational analysis of methionine adenosyltransferase from Leishmania donovani.

scientific article

NRPSsp: non-ribosomal peptide synthase substrate predictor

scientific article published on 29 November 2011

New insights into the isopenicillin N transport in Penicillium chrysogenum

scientific article published on 28 January 2014

PcFKH1, a novel regulatory factor from the forkhead family, controls the biosynthesis of penicillin in Penicillium chrysogenum

scientific article published on 4 June 2015

Penicillium chrysogenum var. halophenolicum, a new halotolerant strain with potential in the remediation of aromatic compounds in high salt environments

scientific article published on 27 April 2011

Post-translational enzyme modification by the phosphopantetheinyl transferase is required for lysine and penicillin biosynthesis but not for roquefortine or fatty acid formation in Penicillium chrysogenum

scientific article published in October 2008

Proteome analysis of the penicillin producer Penicillium chrysogenum: characterization of protein changes during the industrial strain improvement

scientific article

Proteomics shows new faces for the old penicillin producer Penicillium chrysogenum

scientific article (publication date: 2012)

RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: validation studies using beta-lactam genes expression

scientific article published on 12 June 2008

Regulation and compartmentalization of β-lactam biosynthesis.

scientific article published on 31 May 2009

Role of peroxisomes in the biosynthesis and secretion of β-lactams and other secondary metabolites ⬇️

scientific article published on December 11, 2011

The Penicillium Chrysogenum Extracellular Proteome. Conversion from a Food-rotting Strain to a Versatile Cell Factory for White Biotechnology ⬇️

scientific article published on September 7, 2010

The global regulator LaeA controls penicillin biosynthesis, pigmentation and sporulation, but not roquefortine C synthesis in Penicillium chrysogenum

scientific article

The inducers 1,3-diaminopropane and spermidine cause the reprogramming of metabolism in Penicillium chrysogenum, leading to multiple vesicles and penicillin overproduction.

scientific article published on 30 April 2013

The inducers 1,3-diaminopropane and spermidine produce a drastic increase in the expression of the penicillin biosynthetic genes for prolonged time, mediated by the LaeA regulator

article

The regulatory factor PcRFX1 controls the expression of the three genes of β-lactam biosynthesis in Penicillium chrysogenum

article

The transporter CefM involved in translocation of biosynthetic intermediates is essential for cephalosporin production.

scientific article published on February 2009

The unprocessed preprotein form IATC103S of the isopenicillin N acyltransferase is transported inside peroxisomes and regulates its self-processing

scientific article published in April 2008

Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum.

scientific article published on 18 May 2006

Transcriptional upregulation of four genes of the lysine biosynthetic pathway by homocitrate accumulation in Penicillium chrysogenum: homocitrate as a sensor of lysine-pathway distress

scientific article published on 20 August 2009

Transport of substrates into peroxisomes: the paradigm of β-lactam biosynthetic intermediates.

scientific article

Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

scientific article

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