List of works - Mario Chiong

(TTA)n polymorphism in 3-hydroxy-3-methylglutaryl-coenzyme A and response to atorvastatin in coronary artery disease patients

scientific article

ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension

scientific article published on 13 August 2015

Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis: differential effects of sorbitol and mannitol

scientific article published on 24 July 2003

Alteration in mitochondrial Ca(2+) uptake disrupts insulin signaling in hypertrophic cardiomyocytes.

scientific article

An inositol 1,4,5-triphosphate (IP3)-IP3 receptor pathway is required for insulin-stimulated glucose transporter 4 translocation and glucose uptake in cardiomyocytes

scientific article published on 4 August 2010

Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle

scientific article published on 08 December 2020

Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

scientific article published on 09 March 2020

Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.

scientific article published in May 2010

Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis

scientific article published on 01 April 2014

Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial Fibrillation in Elderly Patients.

scientific article published on 23 September 2015

Autophagy as a therapeutic target in cardiovascular disease

scientific article

Autophagy mediates tumor necrosis factor-α-induced phenotype switching in vascular smooth muscle A7r5 cell line.

scientific article

BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism.

scientific article published on 10 December 2015

Biochemical characterization of proteins in the crab Homalaspis plana

scientific article published on 01 September 1995

Cardiomyocyte death: mechanisms and translational implications

scientific article published on 22 December 2011

Cell death and survival through the endoplasmic reticulum-mitochondrial axis

scientific article

Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells

scientific article

Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis

scientific journal article

Comparative subcellular distribution of apyrase from animal and plant sources. Characterization of microsomal apyrase

scientific article

Differential participation of angiotensin II type 1 and 2 receptors in the regulation of cardiac cell death triggered by angiotensin II.

scientific article published on 19 March 2009

Dinámica mitocondrial: un potencial nuevo blanco terapéutico para la insuficiencia cardiaca

scientific article published on 05 August 2011

Direct electrochemical characterization of hyperthermophilic Thermococcus celer metalloenzymes involved in hydrogen production from pyruvate

scientific article published in March 2001

Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury

scientific article published on 01 June 2014

Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure

scientific article published in November 2004

Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic heart failure

scientific article

Effects of carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure

scientific article published in July 2005

Effects of trimetazidine in nonischemic heart failure: a randomized study

scientific article published on 09 January 2014

Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells.

scientific article published on 31 January 2013

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

scientific article

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

scientific article published on December 2011

FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation.

scientific article published on 27 October 2015

GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum-mitochondria coupling.

scientific article published on 12 March 2014

Gln(27)-->Glubeta(2)-adrenergic receptor polymorphism in heart failure patients: differential clinical and oxidative response to carvedilol.

scientific article published in May 2009

Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation.

scientific article published on 22 January 2016

Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes

scientific article published on 20 February 2010

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor

scientific article

Heart energy metabolism and its role in the treatment of heart failure

scientific article published on August 2010

Herp depletion protects from protein aggregation by up-regulating autophagy

scientific article published on 9 October 2013

Human placental ATP-diphosphohydrolase: biochemical characterization, regulation and function

scientific article published on 01 March 1994

Hyperosmotic stress activates p65/RelB NFkappaB in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death

scientific journal article

Hyperosmotic stress-dependent NFκB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes

article

IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB.

scientific article published in November 2005

Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation

scientific article published on 12 May 2017

Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress ⬇️

scientific article published on May 31, 2011

Influence of glucose metabolism on vascular smooth muscle cell proliferation.

scientific article published on January 2013

Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes.

scientific article published on 10 June 2011

Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway

scientific article published on 05 September 2013

Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes

scientific article published on 6 December 2003

Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death

scientific article published on 5 October 2015

Interactions between beta1 and beta2 adrenergic receptor polymorphisms as risk factors for chronic heart failure

scientific article published in November 2008

Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide.

scientific article published on 4 December 2009

Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis

scientific article

Kinetic characteristics of nucleoside mono-, di- and triphosphatase activities of the periplasmic 5'-nucleotidase of Escherichia coli

scientific article published on 01 May 1997

Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype

Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors

scientific journal article

Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure.

scientific article

Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome

scientific article published on 15 January 2009

Mechanisms of cell death: molecular insights and therapeutic perspectives

scientific article published on 01 November 2005

Membrane electrical activity elicits inositol 1,4,5-trisphosphate-dependent slow Ca2+ signals through a Gbetagamma/phosphatidylinositol 3-kinase gamma pathway in skeletal myotubes

scientific article published on 2 March 2006

Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway.

scientific article

Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake.

scientific article published on October 2013

Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation

scientific article

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta

scientific article published on 08 September 2016

Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure

scientific article published on February 7, 2011

Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA

scientific journal article

Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9).

scientific article published on 31 July 2015

Octadecyl silica: a solid phase for protein purification by immunoadsorption

scientific article published in August 1991

Omeprazole, a Specific Gastric Secretion Inhibitor on Oxynticopeptic Cells, Reduces Gizzard Erosion in Broiler Chicks Fed with Toxic Fish Meals

article

Optimization of the growth conditions of the extremely thermophilic microorganisms Thermococcus celer and Pyrococcus woesei

scientific article published in October 1999

Organelle communication: signaling crossroads between homeostasis and disease.

scientific article published on 15 February 2014

Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes ⬇️

scientific article published on 23 May 2008

Oxidative stress after reperfusion with primary coronary angioplasty: lack of effect of glucose-insulin-potassium infusion

scientific article published in February 2002

Oxidative stress and inflammation in heart failure: mechanisms of damage and therapeutic alternatives

scientific article published in August 2007

Oxidative stress in pericardial fluid and plasma and its association with ventricular function

scientific article published in May 2005

Parallel activation of Ca(2+)-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress

scientific article published in August 2010

Persistence of oxidative stress after heart transplantation: a comparative study of patients with heart transplant versus chronic stable heart failure

scientific article published in August 2002

Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor

scientific article published in August 2008

Pleiotropic effects of atorvastatin in heart failure: role in oxidative stress, inflammation, endothelial function, and exercise capacity

scientific article published in April 2008

Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance

scientific article published on 12 June 2018

Purification and biochemical characterization of tellurite-reducing activities from Thermus thermophilus HB8 ⬇️

scientific article published on July 1, 1988

Purification and characterization of an iron-nickel hydrogenase from Thermococcus celer

scientific article published on 01 June 2001

Reactive oxygen species inhibit hyposmotic stress-dependent volume regulation in cultured rat cardiomyocytes

article

Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system.

scientific article

Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species.

scientific article published on 9 October 2009

Relation between oxidative stress, catecholamines, and impaired chronotropic response to exercise in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

scientific article

Relationship between mechanical and metabolic dyssynchrony with left bundle branch block: Evaluation by 18-fluorodeoxyglucose positron emission tomography in patients with non-ischemic heart failure

article

Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure

scientific article published on 01 August 2014

Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension

scientific article

Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling

scientific article published in August 2005

Role of heterotrimeric G protein and calcium in cardiomyocyte hypertrophy induced by IGF-1

scientific article published on 01 April 2014

Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure

Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability.

scientific article published on 28 January 2012

Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts

scientific article published on 30 May 2011

Systemic Oxidative Stress and Endothelial Dysfunction is Associated With an Attenuated Acute Vascular Response to Inhaled Prostanoid in Pulmonary Artery Hypertension Patients

article

Systemic vascular cell adhesion molecule-1 predicts the occurrence of post-operative atrial fibrillation

scientific article published on 05 May 2010

Testosterone induces an intracellular calcium increase by a nongenomic mechanism in cultured rat cardiac myocytes

scientific article

The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling

scientific article

TonEBP suppresses IL-10-mediated immunomodulation

scientific article published on 10 May 2016

Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes

scientific article published in August 2014

Uric acid, xanthine oxidase and heart failure: unresolved issues

scientific article

Vasodilator and hypotensive effects of pure compounds and hydroalcoholic extract of Xenophyllum poposum (Phil) V.A Funk (Compositae) on rats

scientific article published on 26 September 2018

Xanthine-oxidase inhibitors and statins in chronic heart failure: Effects on vascular and functional parameters

article published in 2011

[The role of uric acid in heart failure]

scientific article published on 01 April 2011

List of works by Mario Chiong

(TTA)n polymorphism in 3-hydroxy-3-methylglutaryl-coenzyme A and response to atorvastatin in coronary artery disease patients

ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension

Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis: differential effects of sorbitol and mannitol

Alteration in mitochondrial Ca(2+) uptake disrupts insulin signaling in hypertrophic cardiomyocytes.

An inositol 1,4,5-triphosphate (IP3)-IP3 receptor pathway is required for insulin-stimulated glucose transporter 4 translocation and glucose uptake in cardiomyocytes

Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle

Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.

Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis

Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial Fibrillation in Elderly Patients.

Autophagy as a therapeutic target in cardiovascular disease

Autophagy mediates tumor necrosis factor-α-induced phenotype switching in vascular smooth muscle A7r5 cell line.

BAG3 regulates total MAP1LC3B protein levels through a translational but not transcriptional mechanism.

Biochemical characterization of proteins in the crab Homalaspis plana

Cardiomyocyte death: mechanisms and translational implications

Cell death and survival through the endoplasmic reticulum-mitochondrial axis

Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells

Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis

Comparative subcellular distribution of apyrase from animal and plant sources. Characterization of microsomal apyrase

Differential participation of angiotensin II type 1 and 2 receptors in the regulation of cardiac cell death triggered by angiotensin II.

Dinámica mitocondrial: un potencial nuevo blanco terapéutico para la insuficiencia cardiaca

Direct electrochemical characterization of hyperthermophilic Thermococcus celer metalloenzymes involved in hydrogen production from pyruvate

Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury

Effects of carvedilol on functional capacity, left ventricular function, catecholamines and oxidative stress in patients with chronic heart failure

Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic heart failure

Effects of carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure

Effects of trimetazidine in nonischemic heart failure: a randomized study

Endocytic pathway of exogenous iron-loaded ferritin in intestinal epithelial (Caco-2) cells.

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation.

GLP-1 promotes mitochondrial metabolism in vascular smooth muscle cells by enhancing endoplasmic reticulum-mitochondria coupling.

Gln(27)-->Glubeta(2)-adrenergic receptor polymorphism in heart failure patients: differential clinical and oxidative response to carvedilol.

Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation.

Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor

Heart energy metabolism and its role in the treatment of heart failure

Herp depletion protects from protein aggregation by up-regulating autophagy

Human placental ATP-diphosphohydrolase: biochemical characterization, regulation and function

Hyperosmotic stress activates p65/RelB NFkappaB in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death

Hyperosmotic stress-dependent NFκB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes

IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB.

Increased C-reactive protein plasma levels are not involved in the onset of post-operative atrial fibrillation

Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress ⬇️

Influence of glucose metabolism on vascular smooth muscle cell proliferation.

Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-β prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes.

Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway

Insulin-like growth factor-1 induces an inositol 1,4,5-trisphosphate-dependent increase in nuclear and cytosolic calcium in cultured rat cardiac myocytes

Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death

Interactions between beta1 and beta2 adrenergic receptor polymorphisms as risk factors for chronic heart failure

Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide.

Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis

Kinetic characteristics of nucleoside mono-, di- and triphosphatase activities of the periplasmic 5'-nucleotidase of Escherichia coli

Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype

Local control of nuclear calcium signaling in cardiac myocytes by perinuclear microdomains of sarcolemmal insulin-like growth factor 1 receptors

Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure.

Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome

Mechanisms of cell death: molecular insights and therapeutic perspectives

Membrane electrical activity elicits inositol 1,4,5-trisphosphate-dependent slow Ca2+ signals through a Gbetagamma/phosphatidylinositol 3-kinase gamma pathway in skeletal myotubes

Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway.

Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake.

Mitochondrial metabolism and the control of vascular smooth muscle cell proliferation

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta

Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure

Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA

Novel players in cardioprotection: Insulin like growth factor-1, angiotensin-(1-7) and angiotensin-(1-9).

Octadecyl silica: a solid phase for protein purification by immunoadsorption

Omeprazole, a Specific Gastric Secretion Inhibitor on Oxynticopeptic Cells, Reduces Gizzard Erosion in Broiler Chicks Fed with Toxic Fish Meals

Optimization of the growth conditions of the extremely thermophilic microorganisms Thermococcus celer and Pyrococcus woesei

Organelle communication: signaling crossroads between homeostasis and disease.

Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes ⬇️

Oxidative stress after reperfusion with primary coronary angioplasty: lack of effect of glucose-insulin-potassium infusion

Oxidative stress and inflammation in heart failure: mechanisms of damage and therapeutic alternatives

Oxidative stress in pericardial fluid and plasma and its association with ventricular function

Parallel activation of Ca(2+)-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress

Persistence of oxidative stress after heart transplantation: a comparative study of patients with heart transplant versus chronic stable heart failure

Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor

Pleiotropic effects of atorvastatin in heart failure: role in oxidative stress, inflammation, endothelial function, and exercise capacity