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List of works by Albert Kooistra

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine

scientific article

3D-e-Chem: Structural Cheminformatics Workflows for Computer-Aided Drug Discovery.

scientific article published on 16 January 2018

A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?

scientific article published in January 2018

A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design ⬇️

scientific article published on September 1, 2013

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)

scientific article published on 05 July 2019

Aminergic GPCR-ligand interactions: A chemical and structural map of receptor mutation data

scientific article published on 27 November 2018

Analyzing multitarget activity landscapes using protein-ligand interaction fingerprints: interaction cliffs

scientific article published on 6 February 2015

Chemical Diversity in the G Protein-Coupled Receptor Superfamily

scientific article published on 22 March 2018

Combinatorial Consensus Scoring for Ligand-Based Virtual Fragment Screening: A Comparative Case Study for Serotonin 5-HT(3)A, Histamine H(1), and Histamine H(4) Receptors

scientific article published on 23 April 2015

Covalent Inhibition of the Histamine H3 Receptor

scientific article published on 11 December 2019

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor

scientific article

Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells

scientific article

Discovery of Novel Trypanosoma brucei Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal Structure

scientific article

Electron density fingerprints (EDprints): virtual screening using assembled information of electron density

scientific article published in October 2010

From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands

scientific article

From three-dimensional GPCR structure to rational ligand discovery

scientific article published on January 2014

Function-specific virtual screening for GPCR ligands using a combined scoring method

scientific article

Identification of Ligand Binding Hot Spots of the Histamine H1 Receptor following Structure-Based Fragment Optimization

scientific article

Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain

scientific article

KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space.

scientific article

KLIFS: a structural kinase-ligand interaction database

scientific article published on 22 October 2015

Kinase-Centric Computational Drug Development

article

Mapping histamine H4receptor–ligand binding modes

Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies

scientific article published on 7 November 2011

Molecular interaction fingerprint approaches for GPCR drug discovery

scientific article

PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design.

scientific article published on 23 February 2016

Route to Prolonged Residence Time at the Histamine H1 Receptor: Growing from Desloratadine to Rupatadine

scientific article published on 05 July 2019

Small and colorful stones make beautiful mosaics: fragment-based chemogenomics

scientific article

Structural insights into serotonin receptor ligands polypharmacology

scientific article published on 6 April 2018

Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study

Structure-based virtual screening for fragment-like ligands of the G protein-coupled histamine H4 receptor

Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology.

scientific article published on 14 March 2018

The Landscape of Atypical and Eukaryotic Protein Kinases

scientific article published on 31 October 2019

The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines

scientific article

The receptor concept in 3D: from hypothesis and metaphor to GPCR-ligand structures

scientific article published on 08 August 2014

Utilizing drug-target-event relationships to unveil safety patterns in pharmacovigilance

scientific article published on 08 June 2020

Virtual Fragment Screening: Discovery of Histamine H3 Receptor Ligands Using Ligand-Based and Protein-Based Molecular Fingerprints

scientific article published on 03 December 2012

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