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List of works by Charles A. Brearley

A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut

scientific article

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

scientific article published on 19 September 2018

A Solanum tuberosum inositol phosphate kinase (StITPK1) displaying inositol phosphate-inositol phosphate and inositol phosphate-ADP phosphotransferase activities

scientific article published on 28 April 2008

A defective ABC transporter of the MRP family, responsible for the bean lpa1 mutation, affects the regulation of the phytic acid pathway, reduces seed myo-inositol and alters ABA sensitivity.

scientific article published on 11 March 2011

A lysine accumulation phenotype of ScIpk2Delta mutant yeast is rescued by Solanum tuberosum inositol phosphate multikinase

scientific article published on May 2007

A major role for P2X1 receptors in the early collagen-evoked intracellular Ca2+ responses of human platelets

scientific article published on 01 July 2005

A role for inositol hexakisphosphate in the maintenance of basal resistance to plant pathogens

scientific article published on 16 July 2008

A role of Arabidopsis inositol polyphosphate kinase, AtIPK2alpha, in pollen germination and root growth

scientific article published on 23 December 2004

A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus ⬇️

scientific article

Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro an

scientific article published on 4 August 2005

Arabidopsis inositol phosphate kinases, IPK1 and ITPK1, constitute a metabolic pathway in maintaining phosphate homeostasis.

scientific article

Arabidopsis inositol polyphosphate 6-/3-kinase is a nuclear protein that complements a yeast mutant lacking a functional ArgR-Mcm1 transcription complex

scientific article

Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis

scientific article published on 30 July 2007

Assessment of iron bioavailability from different bread making processes using an in vitro intestinal cell model.

scientific article

AtDGK2, a novel diacylglycerol kinase from Arabidopsis thaliana, phosphorylates 1-stearoyl-2-arachidonoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol and exhibits cold-inducible gene expression

scientific article

Bacteria are important dimethylsulfoniopropionate producers in coastal sediments

scientific article published on 19 August 2019

Both D- and L-glucose polyphosphates mimic D-myo-inositol 1,4,5-trisphosphate: new synthetic agonists and partial agonists at the Ins(1,4,5)P3 receptor

scientific article published on 14 April 2020

Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics

scientific article

Characterization of Arabidopsis mur3 mutations that result in constitutive activation of defence in petioles, but not leaves

scientific article published on 23 July 2008

Characterization of an Arabidopsis inositol 1,3,4,5,6-pentakisphosphate 2-kinase (AtIPK1).

scientific article published on February 2006

Characterization of myo-inositol hexakisphosphate deposits from larval Echinococcus granulosus

scientific article published on 19 June 2006

Conformational Changes in Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase upon Substrate Binding: ROLE OF N-TERMINAL LOBE AND ENANTIOMERIC SUBSTRATE PREFERENCE

scientific article

Crystallization and preliminary X-ray diffraction analysis of inositol 1,3,4,5,6-pentakisphosphate kinase from Arabidopsis thaliana.

scientific article published on 25 December 2009

Effect of phytase on intestinal phytate breakdown, plasma inositol concentrations, and glucose transporter type 4 abundance in muscle membranes of weanling pigs1

scientific article published on 01 September 2019

Effects of fou8/fry1 mutation on sulfur metabolism: is decreased internal sulfate the trigger of sulfate starvation response?

scientific article

Enhanced transcription of the Arabidopsis disease resistance genes RPW8.1 and RPW8.2 via a salicylic acid-dependent amplification circuit is required for hypersensitive cell death

scientific article

Evidence for a SAL1-PAP chloroplast retrograde pathway that functions in drought and high light signaling in Arabidopsis

scientific article published on 29 November 2011

Exogenous phytase and xylanase exhibit opposing effects on real-time gizzard pH in broiler chickens

scientific article published on 02 August 2018

Expression, purification, crystallization and preliminary X-ray diffraction analysis of the apo form of InsP52-K fromArabidopsis thaliana

scientific article

Gibberellin modulation of phosphatidyl-choline turnover in wheat aleurone tissue

scientific article published on 01 December 1987

Improved sensitivity, accuracy and prediction provided by a high-performance liquid chromatography screen for the isolation of phytase-harbouring organisms from environmental samples

scientific article published on 21 December 2020

Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition

scientific article

Inositol hexakisphosphate is a physiological signal regulating the K+-inward rectifying conductance in guard cells.

scientific article published on July 2000

Inositol hexakisphosphate mobilizes an endomembrane store of calcium in guard cells.

scientific article

Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA

scientific article published in 2022

Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping

scientific article published in January 2010

Jasmonate and phytochrome A signaling in Arabidopsis wound and shade responses are integrated through JAZ1 stability

scientific article published on 30 April 2010

Lab-scale preparation and QC of phytase assay substrate from rice bran

scientific article published on 02 May 2019

Land-use influences phosphatase gene microdiversity in soils.

scientific article

Manipulation of plasma myo-inositol in broiler chickens: effect on growth performance, dietary energy, nutrient availability, and hepatic function

scientific article published on 01 January 2019

Membrane specificity of non-monotonic trends in cation-mediated injury to rapidly frozen phospholipid vesicles

scientific article published on 01 September 1991

Molecular dissection of bacterial acrylate catabolism--unexpected links with dimethylsulfoniopropionate catabolism and dimethyl sulfide production.

scientific article published on 5 October 2009

Molecular genetic analysis of a dimethylsulfoniopropionate lyase that liberates the climate-changing gas dimethylsulfide in several marine alpha-proteobacteria and Rhodobacter sphaeroides.

scientific article

PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase

scientific article (publication date: 19 November 1999)

Quantum Blue Reduces the Severity of Woody Breast Myopathy via Modulation of Oxygen Homeostasis-Related Genes in Broiler Chickens

scientific article published on 01 October 2019

Simple synthesis of 32P-labelled inositol hexakisphosphates for study of phosphate transformations.

scientific article

Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced fit structural mechanism

scientific article published on 14 October 2020

Sorting out PtdIns(4,5)P2 and clathrin-coated vesicles in plants

scientific article published on 01 November 2008

Synthesis of inositol phosphate ligands of plant hormone-receptor complexes: pathways of inositol hexakisphosphate turnover

scientific article published in June 2012

The Arabidopsis ATP-binding cassette protein AtMRP5/AtABCC5 is a high affinity inositol hexakisphosphate transporter involved in guard cell signaling and phytate storage

scientific article published on 21 September 2009

The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function

scientific article

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