List of works - Marvin Meyers

4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N-(4-arylpyrrolidin-3-yl)acetamides

scientific article published on 28 May 2019

4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides

scientific article published on 22 March 2019

A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open Access Malaria Box.

scientific article published on 16 January 2018

Antifungal Phenothiazines: Optimization, Characterization of Mechanism, and Modulation of Neuroreceptor Activity.

scientific article

Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency

scientific article

Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors

scientific article published on February 2016

Chemical Approaches to Inhibiting the Hepatitis B Virus Ribonuclease H.

scientific article published on 22 March 2018

Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model

scientific article published on 8 January 2018

Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy

scientific article published on 12 June 2019

Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy.

scientific article published on August 2010

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

scientific article published on 09 September 2018

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds

scientific article published on 22 August 2011

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain

scientific article published on 19 August 2011

Editorial: the medicinal chemistry of novel approaches for the treatment of malaria

scientific article published in January 2012

Endonuclease Activity Inhibition of the NS1 Protein of Parvovirus B19 as a Novel Target for Antiviral Drug Development

scientific article published on 26 February 2019

Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes

scientific article

Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues

scientific article published in November 2001

Evaluation of aminohydantoins as a novel class of antimalarial agents.

scientific article

Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents

scientific article

Facile synthesis of high affinity styrylpyridine systems as inherently fluorescent ligands for the estrogen receptor

scientific article published on 01 December 1998

Hepatitis B virus genetic diversity has minimal impact on sensitivity of the viral ribonuclease H to inhibitors.

scientific article

Hepatitis B virus replication is blocked by a 2-hydroxyisoquinoline-1,3(2H,4H)-dione (HID) inhibitor of the viral ribonuclease H activity

scientific article

Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity

scientific article

Identification of (R)-6-(1-(4-cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic acid, a highly potent and selective nonsteroidal mineralocorticoid receptor antagonist

scientific article published on 30 April 2014

MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria

scientific article published on 11 October 2018

Novel tetrahydro-beta-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

scientific article published on 25 May 2007

Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea

scientific article published on 23 February 2016

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion.

scientific article published in October 2017

Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

scientific article

Quinine bis-conjugates with quinolone antibiotics and peptides: synthesis and antimalarial bioassay

scientific article published on 16 October 2012

Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts

scientific article published on January 2012

Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome

scientific article

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

scientific article

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

scientific article

Synthesis and Evaluation of Troponoids as a New Class of Antibiotics

scientific article published on 08 November 2018

Synthesis and antimalarial bioassay of quinine - peptide conjugates

scientific article published on 01 October 2013

Synthesis of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate

scientific article published on 01 August 2009

Synthesis, antimalarial properties and 2D-QSAR studies of novel triazole-quinine conjugates.

scientific article

Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells

scientific article published on 14 May 2019

The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes

scientific article

The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis

scientific article published on 3 October 2017

Troponoids Can Inhibit Growth of the Human Fungal Pathogen Cryptococcus neoformans

scientific article

List of works by Marvin Meyers

4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-N-(4-arylpyrrolidin-3-yl)acetamides

4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides

A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open Access Malaria Box.

Antifungal Phenothiazines: Optimization, Characterization of Mechanism, and Modulation of Neuroreceptor Activity.

Benzothiophene inhibitors of MK2. Part 2: improvements in kinase selectivity and cell potency

Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors

Chemical Approaches to Inhibiting the Hepatitis B Virus Ribonuclease H.

Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model

Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy

Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy.

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain

Editorial: the medicinal chemistry of novel approaches for the treatment of malaria

Endonuclease Activity Inhibition of the NS1 Protein of Parvovirus B19 as a Novel Target for Antiviral Drug Development

Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes

Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues

Evaluation of aminohydantoins as a novel class of antimalarial agents.

Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents

Facile synthesis of high affinity styrylpyridine systems as inherently fluorescent ligands for the estrogen receptor

Hepatitis B virus genetic diversity has minimal impact on sensitivity of the viral ribonuclease H to inhibitors.

Hepatitis B virus replication is blocked by a 2-hydroxyisoquinoline-1,3(2H,4H)-dione (HID) inhibitor of the viral ribonuclease H activity

Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity

Identification of (R)-6-(1-(4-cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1H-pyrazol-3-yl)-2-methoxynicotinic acid, a highly potent and selective nonsteroidal mineralocorticoid receptor antagonist

MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria

Novel tetrahydro-beta-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2)

Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion.

Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)

Quinine bis-conjugates with quinolone antibiotics and peptides: synthesis and antimalarial bioassay

Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts

Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Synthesis and Evaluation of Troponoids as a New Class of Antibiotics

Synthesis and antimalarial bioassay of quinine - peptide conjugates

Synthesis of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate

Synthesis, antimalarial properties and 2D-QSAR studies of novel triazole-quinine conjugates.

Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells

The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes

The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis

Troponoids Can Inhibit Growth of the Human Fungal Pathogen Cryptococcus neoformans