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List of works by Roisin Mcmahon

Disarming Burkholderia pseudomallei : Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo

scientific article

Dissection of the multiple sclerosis associated DR2 haplotype

scientific article published on 02 June 2008

Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors.

scientific article published on 30 January 2014

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

scientific article

Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA

scientific article published on 01 January 2022

Life inside and out: making and breaking protein disulfide bonds in Chlamydia

scientific article published on 21 January 2019

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis

article

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development

scientific article published on 19 September 2019

P-glycoprotein inhibition: the past, the present and the future.

scientific article published on October 2011

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.

scientific article published on 26 November 2015

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase

scientific article

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis

scientific article

T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides

scientific article

The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis

scientific article published on April 2014

The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.

scientific article published on July 2005

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA

scientific article

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