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List of works by Angela Nebbioso

1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

scientific article published on 08 July 2014

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

scientific article published on 21 December 2015

ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias

scientific article

Acute myeloid leukemia: therapeutic impact of epigenetic drugs

scientific article

Analysis of chromatin-nuclear receptor interactions by laser-chromatin immunoprecipitation

scientific article

Anticancer activities of anthocyanin extract from genotyped Solanum tuberosum L. “Vitelotte”

Antiproliferative, antibacterial and antifungal activity of the lichen Xanthoria parietina and its secondary metabolite parietin

scientific article

Antiviral Activity of Vitis vinifera Leaf Extract against SARS-CoV-2 and HSV-1

scientific article published in 2021

Biological interactions of biocompatible and water-dispersed MoS nanosheets with bacteria and human cells

scientific article published in Scientific Reports

Bispyridinium dienes: histone deacetylase inhibitors with selective activities

scientific article published on 21 April 2007

Cancer epigenetics: Moving forward.

scientific article published on 7 June 2018

Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides

scientific article published in May 2005

Comparative Phytochemical Characterization, Genetic Profile, and Antiproliferative Activity of Polyphenol-Rich Extracts from Pigmented Tubers of Different Solanum tuberosum Varieties

scientific article published on 06 January 2020

Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells

scientific article published on August 2006

Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392.

scientific article published on 24 February 2014

Cytotoxic Potential of the Marine Diatom Thalassiosira rotula: Insights into Bioactivity of 24-Methylene Cholesterol

scientific article published in 2022

DOT1L: a key target in normal chromatin remodelling and in mixed-lineage leukaemia treatment

scientific article published on 28 December 2019

Death Receptor Pathway Activation and Increase of ROS Production by the Triple Epigenetic Inhibitor UVI5008

article

Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide Derivatives as Potent and Selective HDAC Inhibitors

scientific article published on 24 May 2012

Design, synthesis and biological evaluation of novel compounds with conjugated structure as anti-tumor agents

scientific article

Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death.

scientific article published on 29 December 2017

Developing novel non-hydroxamate histone deacetylase inhibitors: the chelidamic warhead

Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells

scientific article published on 12 December 2012

Enzymatic and Biological Characterization of Novel Sirtuin Modulators against Cancer

scientific article published on 12 November 2019

Epigenetic profiling of the antitumor natural product psammaplin A and its analogues

scientific article published on 15 December 2010

Evaluation of a large library of (thiazol-2-yl)hydrazones and analogues as histone acetyltransferase inhibitors: enzyme and cellular studies.

scientific article

Feijoa sellowiana derived natural Flavone exerts anti-cancer action displaying HDAC inhibitory activities

scientific article published on 25 May 2007

Genetic mutations in epigenetic modifiers as therapeutic targets in acute myeloid leukemia

scientific article published on 30 May 2015

Genista sessilifolia DC. extracts induce apoptosis across a range of cancer cell lines.

scientific article

Growth factor-antagonized rexinoid apoptosis involves permissive PPARgamma/RXR heterodimers to activate the intrinsic death pathway by NO.

scientific article

HDAC inhibitors repress BARD1 isoform expression in acute myeloid leukemia cells via activation of miR-19a and/or b.

scientific article

HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2.

scientific article

HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation

scientific article published on 16 July 2010

Histone Deacetylase Inhibitors: Recent Insights from Basic to Clinical Knowledge & Patenting of Anti-Cancer Actions ⬇️

scientific article published on January 1, 2011

Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia

scientific article published on 29 May 2008

Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation.

scientific article published on 5 October 2009

Histone deacetylase inhibitors: a patent review (2009 - 2011).

scientific article published on 25 October 2012

Histone deacetylase inhibitors: clinical implications for hematological malignancies

scientific article

Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases

scientific article published on 30 December 2008

Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells

scientific article published on March 2014

Identification of Two New Synthetic Histone Deacetylase Inhibitors That Modulate Globin Gene Expression in Erythroid Cells from Healthy Donors and Patients with Thalassemia

article

Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

scientific article published on 06 May 2019

Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases.

scientific article published on 11 April 2008

Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors

scientific article published on May 2010

Indole-derived psammaplin A analogues as epigenetic modulators with multiple inhibitory activities

scientific article

Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer

scientific article published on 16 December 2019

Marine-Derived Secondary Metabolites as Promising Epigenetic Bio-Compounds for Anticancer Therapy

scientific article published on 31 December 2020

Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells

scientific article published on 18 June 2009

Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability

scientific article published on 22 May 2008

Natural compounds in epigenetics: a current view.

scientific article

New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations

scientific article published on 12 September 2008

Novel N-hydroxybenzamide-based HDAC inhibitors with branched CAP group

scientific article published on 29 September 2009

Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity.

scientific article published on 8 July 2014

Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity

scientific article published on 4 March 2011

Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity

scientific article published on 4 April 2007

Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities

scientific article published on 22 March 2008

Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart

scientific article

PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia.

scientific article

Piroxicam and cisplatin in a mouse model of peritoneal mesothelioma

scientific article published on October 2006

Psidium guajava L. anti-neoplastic effects: induction of apoptosis and cell differentiation.

scientific article

Pyrrole-based hydroxamates and 2-aminoanilides: histone deacetylase inhibition and cellular activities

scientific article

Rarity of Human T Helper 17 Cells Is due to Retinoic Acid Orphan Receptor-Dependent Mechanisms that Limit Their Expansion

scientific article published on 09 February 2012

Recent insights into Histone Acetyltransferase-1: biological function and involvement in pathogenesis

scientific article published on 04 October 2020

Retracted: Epigenetic Silencing of Peroxisome Proliferator-Activated Receptor γ Is a Biomarker for Colorectal Cancer Progression and Adverse Patients' Outcome

retracted article

Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor

scientific article

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

scientific article

Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes ⬇️

scientific article

Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile

scientific article published on 19 January 2011

Sirtuins and Disease: The Road Ahead ⬇️

scientific article published on January 31, 2012

Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties

scientific article published on November 2006

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

scientific article

Synthesis and Biological Properties of Novel, Uracil-Containing Histone Deacetylase Inhibitors

scientific article published on 01 October 2006

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors

scientific article published on July 2007

Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities

scientific article published in September 2008

TNF-related apoptosis-inducing ligand: signalling of a 'smart' molecule.

scientific article published on 28 December 2007

The new low-toxic histone deacetylase inhibitor S-(2) induces apoptosis in various acute myeloid leukaemia cells.

scientific article published on August 2012

Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses.

scientific article published on 15 September 2017

Trials with ‘epigenetic’ drugs: An update ⬇️

scientific article published on October 6, 2012

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

scientific article published on 26 December 2004

Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence

scientific article published on 16 January 2020

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression.

scientific article published on 30 January 2012

epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

scientific article

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