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List of works by Michael Sanderson

A comprehensive pharmacokinetic/pharmacodynamics analysis of the novel IGF1R/INSR inhibitor BI 893923 applying in vitro, in vivo and in silico modeling techniques

scientific article published on 9 May 2016

A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

scientific article published on February 2006

ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx

scientific article

An allometric pharmacokinetic/pharmacodynamics model for BI 893923, a novel IGF-1 receptor inhibitor

scientific article published on 27 February 2017

BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis

scientific article

Control of ErbB signaling through metalloprotease mediated ectodomain shedding of EGF-like factors

scientific article published on June 2006

Exosomes: from biogenesis and secretion to biological function

scientific article

Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion.

scientific article

Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.

scientific article published on October 2006

Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo.

scientific article

L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells.

scientific article published on 9 October 2006

Purification and molecular characterization of recombinant rat betacellulin

scientific journal article

Syk and Lyn mediate distinct Syk phosphorylation events in FcɛRI-signal transduction: implications for regulation of IgE-mediated degranulation

scientific article published on 15 September 2010

Syk: a novel target for treatment of inflammation in lung disease

scientific article published on June 2009

Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker

scientific article

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