List of works - Gunnar Schotta

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

scientific article published on 15 June 2016

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

scientific article

A spherical harmonics intensity model for 3D segmentation and 3D shape analysis of heterochromatin foci.

scientific article published on 17 March 2016

Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.

scientific article

Atrx promotes heterochromatin formation at retrotransposons

scientific article published on 26 May 2015

BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV

scientific article published on 29 March 2019

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

scientific article published on 01 February 2019

CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.

scientific article published on January 2012

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing

scientific article

Comment on "Biomolecular dynamics and binding studies in the living cell" by Stephan Diekmann and Christian Hoischen

scientific article published on 22 November 2013

Comparative computational analysis of pluripotency in human and mouse stem cells.

scientific article

Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repair

scientific article published on 4 July 2014

Controlled expression of tagged proteins in Drosophila using a new modular P-element vector system.

scientific article published in January 2000

Cross-species Analyses Unravel the Complexity of H3K27me3 and H4K20me3 in the Context of Neural Stem Progenitor Cells.

scientific article published on 03 May 2016

Dynamic changes of the epigenetic landscape during cellular differentiation.

scientific article published on December 2013

Emergence of cancer stem cells in hepatocellular carcinoma

scientific article published on 8 January 2015

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

scientific article published on 19 January 2021

Epigenetic regulation of development by histone lysine methylation.

scientific article published on 05 May 2010

Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina

scientific article published in August 2013

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

scientific article published on 01 April 2021

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.

scientific article published on 29 May 2013

H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization

scientific journal article

Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons.

scientific article published on 30 October 2014

Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication

scientific article published on 4 August 2017

Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks

scientific article (publication date: 2012)

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

scientific journal article

Loss of KDM6A confers drug resistance in acute myeloid leukemia

scientific article published on 14 June 2019

Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration

scientific article published on October 2016

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

scientific article

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.

scientific article published on 25 July 2016

Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.

scientific article published on 23 January 2013

Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation

scientific article published on 14 October 2021

PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.

scientific article published on 22 August 2008

Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila

scientific article

Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2

scientific article published on 01 September 2019

Production of Small Noncoding RNAs from the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila melanogaster

scientific article published on 24 August 2016

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

scientific article published on 23 June 2021

Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing

scientific article published on 24 April 2014

Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells

scientific article

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

scientific article

SU(VAR)3-9 is a conserved key function in heterochromatic gene silencing.

scientific article

Silencing of endogenous retroviruses by heterochromatin

scientific article published on 3 February 2017

Specificity, propagation, and memory of pericentric heterochromatin

scientific article

Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila

scientific article

Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells

scientific article

Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination

scientific article

Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin.

scientific article published on 18 April 2013

The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis

scientific article published on 01 December 2018

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

scientific article published on 23 January 2017

The compact view on heterochromatin

scientific article published on 23 August 2013

The indexing potential of histone lysine methylation.

scientific article published on January 2004

The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice.

scientific article published on 28 April 2011

Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome

scientific article published in January 2004

ε-globin expression is regulated by SUV4-20h1.

scientific article published on 22 January 2016

List of works by Gunnar Schotta

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

A spherical harmonics intensity model for 3D segmentation and 3D shape analysis of heterochromatin foci.

Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.

Atrx promotes heterochromatin formation at retrotransposons

BZLF1 interacts with chromatin remodelers promoting escape from latent infections with EBV

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing

Comment on "Biomolecular dynamics and binding studies in the living cell" by Stephan Diekmann and Christian Hoischen

Comparative computational analysis of pluripotency in human and mouse stem cells.

Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repair

Controlled expression of tagged proteins in Drosophila using a new modular P-element vector system.

Cross-species Analyses Unravel the Complexity of H3K27me3 and H4K20me3 in the Context of Neural Stem Progenitor Cells.

Dynamic changes of the epigenetic landscape during cellular differentiation.

Emergence of cancer stem cells in hepatocellular carcinoma

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

Epigenetic regulation of development by histone lysine methylation.

Epigenetics of eu- and heterochromatin in inverted and conventional nuclei from mouse retina

Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.

H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization

Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons.

Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication

Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

Loss of KDM6A confers drug resistance in acute myeloid leukemia

Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.

Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.

Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation

PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.

Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila

Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2

Production of Small Noncoding RNAs from the flamenco Locus Is Regulated by the gypsy Retrotransposon of Drosophila melanogaster

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing

Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

SU(VAR)3-9 is a conserved key function in heterochromatic gene silencing.

Silencing of endogenous retroviruses by heterochromatin

Specificity, propagation, and memory of pericentric heterochromatin

Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila

Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells

Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination

Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin.

The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis

The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

The compact view on heterochromatin

The indexing potential of histone lysine methylation.

The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice.

Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome

ε-globin expression is regulated by SUV4-20h1.