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List of works by Mitsuru Sugawara

A general approach for the prediction of the intestinal absorption of drugs: regression analysis using the physicochemical properties and drug-membrane electrostatic interaction

scientific article published in August 1998

A new system for the prediction of drug absorption using a pH-controlled Caco-2 model: evaluation of pH-dependent soluble drug absorption and pH-related changes in absorption

scientific article

Age- and gender-related differences in carbohydrate concentrations of alpha1-acid glycoprotein variants and the effects of glycoforms on their drug-binding capacities

scientific article published on 22 November 2002

Alpha‐1‐Acid Glycoprotein Concentration and the Protein Binding of Disopyramide in Healthy Subjects ⬇️

scientific article published on 01 May 1995

An in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs

scientific article published in September 2003

Carrier-mediated transport system for choline and its related quaternary ammonium compounds on rat intestinal brush-border membrane

scientific article published on 01 November 1992

Changes in the permeation rate of organic anions through the intestinal brush-border membrane with membrane surface potential

scientific article published on 01 February 1994

Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta

scientific article

Comparison of the transport characteristics of ceftibuten in rat renal and intestinal brush-border membranes

scientific article published on 01 September 1995

Detection of risk factors related to administration suspension and severe neutropenia in gemcitabine and nab-paclitaxel treatment

scientific article published on 26 October 2020

Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract

scientific article published in June 2001

Differential binding of disopyramide and warfarin enantiomers to human alpha(1)-acid glycoprotein variants

scientific article published on December 2003

Effect of 5-Fluorouracil Treatment on SN-38 Absorption from Intestine in Rats ⬇️

scientific article published on January 1, 2011

Effect of membrane surface potential on the uptake and the inhibition of cationic compounds in rat intestinal brush-border membrane vesicles and liposomes

scientific article published in March 1995

Effect of membrane surface potential on the uptake of anionic compounds by liposomes

scientific article published on 01 June 1994

Effect of palonosetron and dexamethasone administration on the prevention of gastrointestinal symptoms in hepatic arterial chemoembolization with epirubicin

scientific article published on 16 November 2019

Effects of interactions between drugs on the renal excretion of trientine in rats--acetazolamide and furosemide increase trientine excretion

scientific article published on 01 December 1999

Estimation of the duration after methamphetamine injection using a pharmacokinetic model in suspects who caused fatal traffic accidents

scientific article published on 13 April 2012

Evaluation of effects of polymorphism for metabolic enzymes on pharmacokinetics of carvedilol by population pharmacokinetic analysis

scientific article published in March 2007

Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A

scientific journal article

Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate

scientific article

Functional analysis of phenolsulfonphthalein transport system in Long-Evans Cinnamon rats

scientific article published on 4 October 2007

Hypertriglyceridemia induced by S-1: A novel case report and review of the literature

scientific article published on 16 September 2020

Impact of histamine type-2 receptor antagonists on the anticancer efficacy of gefitinib in patients with non-small cell lung cancer

scientific article published on 07 October 2020

Improvement of renal function estimation equations for elderly Japanese people

scientific article published on 05 September 2018

In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid

scientific article published on 07 October 2010

Influence of continuous venovenous haemodiafiltration on the pharmacokinetics of tacrolimus in liver transplant recipients with small-for-size grafts

scientific article

Inhibitory effect of ezetimibe can be prevented by an administration interval of 4 h between α-tocopherol and ezetimibe

scientific article published on 27 December 2016

Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein

scientific article published on 26 July 2008

Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A.

scientific article

Ionic strength has a greater effect than does transmembrane electric potential difference on permeation of tryptamine and indoleacetic acid across Caco-2 cells

scientific article published in August 2002

Ionic-diffusion Potential-dependent Transport of a New Quinolone, Sparfloxacin, Across Rat Intestinal Brush-border Membrane ⬇️

scientific article published on 01 June 1998

Kinetic study of anti-viral ribavirin uptake mediated by hCNT3 and hENT1 in Xenopus laevis oocytes.

scientific article published on 6 January 2010

Liquid chromatographic method for the determination of ganciclovir and/or acyclovir in human plasma using pulsed amperometric detection

scientific article published in November 2002

Major role of organic anion transporters in the uptake of phenolsulfonphthalein in the kidney

scientific article published in August 2003

Mechanism of the inhibitory effect of imipramine on the Na+-dependent transport of L-glutamic acid in rat intestinal brush-border membrane

scientific article published in March 1998

Membrane-potential-dependent uptake of tryptamine by rat intestinal brush-border membrane vesicles

scientific article published on 01 November 1992

Multidrug Resistance Protein 2 Implicates Anticancer Drug-Resistance to Sorafenib ⬇️

scientific article published on January 1, 2011

Pharmacokinetic properties of lutein emulsion after oral administration to rats and effect of food intake on plasma concentration of lutein

scientific article published on 15 February 2011

Pharmacokinetics and dose adjustment of etoposide administered in a medium-dose etoposide, cyclophosphamide and total body irradiation regimen before allogeneic hematopoietic stem cell transplantation

scientific article published on 08 August 2016

Pharmacokinetics of mycophenolic acid after haplo-hematopoietic stem cell transplantation in Japanese recipients

scientific article published on 22 December 2020

Phenolsulfonphthalein transport by potential-sensitive urate transport system

scientific article published in August 2005

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

scientific journal article

Protective Effect of Soy Isoflavone Genistein on Ischemia-Reperfusion in the Rat Small Intestine ⬇️

scientific article published on 01 January 2011

Protective effect of lutein after ischemia-reperfusion in the small intestine

scientific article published on 28 January 2011

Purification and liposomal reconstitution of the oligopeptide transport activity in rat renal cortex using ceftibuten-affinity chromatography

scientific article published on 01 January 1998

Purification by ceftibuten-affinity chromatography and the functional reconstitution of oligopeptide transporter(s) in rat intestinal brush-border membrane

scientific article published on 01 March 1998

Purification method for alpha-1-acid glycoprotein with subsequent high-performance liquid chromatographic determination of monosaccharides in plasma of healthy subjects and patients with renal insufficiency

scientific article published on 01 October 1995

Rapid and simple method for the determination of alpha 1-acid glycoprotein in serum by column liquid chromatography

scientific article published on 01 November 1992

Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.

scientific article

Ribavirin uptake by cultured human choriocarcinoma (BeWo) cells and Xenopus laevis oocytes expressing recombinant plasma membrane human nucleoside transporters

scientific article published on 3 November 2006

Schedule-Dependent Cytotoxicity of Etoposide (VP-16) and Cyclophosphamide in Leukemia Cell Line K-562 ⬇️

scientific article published on January 1, 2012

Single-step isolation method for six glycoforms of human α1-acid glycoprotein by hydroxylapatite chromatography and study of their binding capacities for disopyramide ⬇️

scientific article published on December 5, 1997

Stereoselective metabolism of racemic carvedilol by UGT1A1 and UGT2B7, and effects of mutation of these enzymes on glucuronidation activity

scientific article

Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle

scientific journal article

Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites

scientific article published in August 2005

Successful transplantation of rat hearts subjected to extended cold preservation with a novel preservation solution

scientific article published on 04 April 2012

The Effect of Membrane Surface Potential on the Permeability of Anionic Compounds Across the Apical Membrane in Human Intestinal Epithelial (Caco-2) Cells ⬇️

scientific article published on July 1, 1997

The Mechanism of Excretion of Trientine from the Rat Kidney: Trientine is not Recognized by the H+/Organic Cation Transporter ⬇️

scientific article published on 01 April 1997

The diversity of Na(+)-independent uptake systems for polyamines in rat intestinal brush-border membrane vesicles

scientific article published on 01 September 1993

The intestinal transport mechanism of fluoroquinolones: inhibitory effect of ciprofloxacin, an enoxacin derivative, on the membrane potential-dependent uptake of enoxacin

scientific article published on 01 September 1995

The presence of an Na+/spermine antiporter in the rat renal brush-border membrane

scientific article published on 01 March 1999

The transport mechanisms of organic cations and their zwitterionic derivatives across rat intestinal brush-border membrane. 1. Binding characteristics to the bio- and lipid-membranes

scientific article published on 01 February 1993

The transport mechanisms of organic cations and their zwitterionic derivatives across rat intestinal brush-border membrane. II. Comparison of the membrane potential effect on the uptake by membrane vesicles

scientific article published on 01 October 1993

The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations

scientific article published in September 2005

Transport characteristics of ceftibuten, cefixime and cephalexin across human jejunal brush-border membrane ⬇️

scientific article published on 01 December 1991

Transport characteristics of cephalosporin antibiotics across intestinal brush-border membrane in man, rat and rabbit

scientific article published on 01 December 1992

Transport mechanism of ceftibuten, a dianionic cephem, in rat renal brush-border membrane

scientific article published on 01 April 1995

Transport mechanisms of nucleosides and the derivative, 6-mercaptopurine riboside across rate intestinal brush-border membranes

scientific article published in January 1996

Uptake of dipeptide and beta-lactam antibiotics by the basolateral membrane vesicles prepared from rat kidney

scientific article

beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

scientific journal article

cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1

scientific journal article

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