List of works - Makoto Kimura

2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA) inhibits trichothecene production by Fusarium graminearum through suppression of Tri6 expression.

scientific article published on 15 July 2015

4-O-Glucosylation of Trichothecenes by Fusarium Species: A Phase II Xenobiotic Metabolism for t-Type Trichothecene Producers

scientific article published in 2021

4-O-acetylation and 3-O-acetylation of trichothecenes by trichothecene 15-O-acetyltransferase encoded by Fusarium Tri3.

scientific article

A fluorescent antibiotic resistance marker for rapid production of transgenic rice plants

scientific article published on 4 November 2005

A model transgenic cereal plant with detoxification activity for the estrogenic mycotoxin zearalenone

scientific article published in October 2005

A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

scientific article

A screening system for inhibitors of trichothecene biosynthesis: hydroxylation of trichodiene as a target

scientific article published in February 2008

A wheat xylanase inhibitor gene, Xip-I, but not Taxi-I, is significantly induced by biotic and abiotic signals that trigger plant defense.

scientific article published in May 2005

ATF-1 transcription factor regulates the expression of ccg-1 and cat-1 genes in response to fludioxonil under OS-2 MAP kinase in Neurospora crassa

scientific article

Acetyltransferase activity in Pseudomonas sp. capable of acetylating the C-4 hydroxyl group of nivalenol-type trichothecenes

scientific article published on 21 October 2016

AtNFXL1, an Arabidopsis homologue of the human transcription factor NF-X1, functions as a negative regulator of the trichothecene phytotoxin-induced defense response.

scientific article published on 06 December 2007

Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells.

scientific article

Characterization of genes encoding metal tolerance proteins isolated from Nicotiana glauca and Nicotiana tabacum.

scientific article

Characterization of the acivicin effects on trichothecene production by Fusarium graminearum species complex.

scientific article published on 6 September 2016

Circadian Rhythm of Circumnutation in Inflorescence Stems of Arabidopsis

scientific article published on 20 May 2005

Cloning and characterization of genes specifically expressed during infection stages in the rice blast fungus.

scientific article

Cloning and characterization of six highly similar endo-1,3-beta-glucanase genes in hexaploid wheat

scientific article published on 3 November 2006

Cloning of the blasticidin S deaminase gene (BSD) from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae

scientific article published on January 1994

Comparison of the paralogous transcription factors AraR and XlnR in Aspergillus oryzae.

scientific article published on 13 April 2018

Concordant evolution of trichothecene 3-O-acetyltransferase and an rDNA species phylogeny of trichothecene-producing and non-producing fusaria and other ascomycetous fungi

scientific article published in February 2005

Conferring cadmium resistance to mature tobacco plants through metal-adsorbing particles of tomato mosaic virus vector

scientific article published in May 2006

Copper elicits an increase in cytosolic free calcium in cultured tobacco cells

scientific article published on 7 November 2005

Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc

scientific article

Crystallization and preliminary X-ray diffraction studies of blasticidin S deaminase from Aspergillus terreus

scientific article published on 01 February 1999

Development of a simultaneous liquid chromatography/tandem mass spectrometric method for the determination of type B trichothecenes, their derivatives, and precursors in wheat

article

Effect of disrupting the trichothecene efflux pump encoded by FgTri12 in the nivalenol chemotype of Fusarium graminearum

Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi

article

Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene.

scientific article published on 4 January 2005

Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin

scientific article published on 26 March 2018

Features ofTri101, the Trichothecene 3-O-Acetyltransferase Gene, Related to the Self-defense Mechanism inFusarium graminearum

article

Fusarium Tri4 encodes a key multifunctional cytochrome P450 monooxygenase for four consecutive oxygenation steps in trichothecene biosynthesis.

scientific article published on 12 December 2006

Fusarium phytotoxin trichothecenes have an elicitor-like activity in Arabidopsis thaliana, but the activity differed significantly among their molecular species

scientific article

Genetically engineered Fusarium as a tool to evaluate the effects of environmental factors on initiation of trichothecene biosynthesis

scientific article published on 15 August 2007

Genotyping of benzimidazole-resistant and dicarboximide-resistant mutations in Botrytis cinerea using real-time polymerase chain reaction assays

scientific article

Hydroxylations of trichothecene rings in the biosynthesis of Fusarium trichothecenes: evolution of alternative pathways in the nivalenol chemotype.

scientific article published on 27 April 2016

Identification and Characterization of Small Molecule Compounds That Modulate Trichothecene Production by Fusarium graminearum

scientific article published on 26 March 2018

Identification and characterization of an inhibitor of trichothecene 3-O-acetyltransferase, TRI101, by the chemical array approach

scientific article

Identification of OS-2 MAP kinase-dependent genes induced in response to osmotic stress, antifungal agent fludioxonil, and heat shock in Neurospora crassa.

scientific article

Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein.

scientific article

Identification of amino acids negatively affecting Fusarium trichothecene biosynthesis

scientific article published on 28 September 2018

Identification of multiple highly similar XIP-type xylanase inhibitor genes in hexaploid wheat

scientific article published on 9 July 2007

Impact of nitrogen metabolism-associated culture pH changes on regulation of Fusarium trichothecene biosynthesis: revision of roles of polyamine agmatine and transcription factor AreA

scientific article published on 18 August 2020

Increased metabolite production by deletion of an HDA1-type histone deacetylase in the phytopathogenic fungi, Magnaporthe oryzae (Pyricularia oryzae) and Fusarium asiaticum.

scientific article

Inhibition of Fusarium trichothecene biosynthesis by yeast extract components extractable with ethyl acetate

scientific article published on 27 August 2018

Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae

scientific article published in December 2009

Involvement of an SRF-MADS protein McmA in regulation of extracellular enzyme production and asexual/sexual development in Aspergillus nidulans

scientific article published on 11 March 2016

Involvement of the osmosensor histidine kinase and osmotic stress-activated protein kinases in the regulation of secondary metabolism in Fusarium graminearum.

scientific article published on 19 September 2007

L-Threonine and its analogue added to autoclaved solid medium suppress trichothecene production by Fusarium graminearum.

scientific article published on 29 March 2017

McmA-dependent and -independent regulatory systems governing expression of ClrB-regulated cellulase and hemicellulase genes in Aspergillus nidulans

scientific article published on 2 September 2016

Metabolism of zearalenone by genetically modified organisms expressing the detoxification gene from Clonostachys rosea.

scientific article

Microbial toxins in plant-pathogen interactions: Biosynthesis, resistance mechanisms, and significance

scientific article

Multilocus genotyping and molecular phylogenetics resolve a novel head blight pathogen within the Fusarium graminearum species complex from Ethiopia.

scientific article

New TAXI-type xylanase inhibitor genes are inducible by pathogens and wounding in hexaploid wheat

scientific article published in October 2004

Nicotinamide Mononucleotide Potentiates Resistance to Biotrophic Invasion of Fungal Pathogens in Barley

scientific article published on 08 March 2021

Nicotinamide mononucleotide and related metabolites induce disease resistance against fungal phytopathogens in Arabidopsis and barley.

scientific article published on 25 July 2017

Oligosaccharides containing an α-(1→2) (glucosyl/xylosyl)-fructosyl linkage as inducer molecules of trichothecene biosynthesis for Fusarium graminearum.

scientific article published on 16 September 2016

Pattern of N gene-mediated systemic hypersensitive response and turnover of viral replicase protein in tobacco

scientific article published on 23 July 2004

Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana

scientific article published on 10 April 2007

Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum.

scientific article published on 6 August 2015

Proteome analysis of wheat lemma.

scientific article published in November 2003

Re-examination of genetic and nutritional factors related to trichothecene biosynthesis in Fusarium graminearum.

scientific article published on 28 September 2015

Reduced Toxicity of Trichothecenes, Isotrichodermol, and Deoxynivalenol, by Transgenic Expression of the Tri101 3-O-Acetyltransferase Gene in Cultured Mammalian FM3A Cells

scientific article published on 10 November 2019

Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene

scientific article published on 5 January 2007

Regulation of genes encoding cellulolytic enzymes by Pal-PacC signaling in Aspergillus nidulans

scientific article

Roles of putative His-to-Asp signaling modules HPT-1 and RRG-2, on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa

scientific article published in March 2007

Screening of putative oxygenase genes in the Fusarium graminearum genome sequence database for their role in trichothecene biosynthesis

scientific article published in October 2005

Site-specific DNA double-strand break generated by I-SceI endonuclease enhances ectopic homologous recombination in Pyricularia oryzae

scientific article

Spiroethers of German chamomile inhibit production of aflatoxin G and trichothecene mycotoxin by inhibiting cytochrome P450 monooxygenases involved in their biosynthesis.

scientific article published on 19 May 2008

Substrate specificities of Fusarium biosynthetic enzymes explain the genetic basis of a mixed chemotype producing both deoxynivalenol and nivalenol-type trichothecenes

scientific article published on 22 January 2020

The 1.48 A resolution crystal structure of the homotetrameric cytidine deaminase from mouse.

scientific article published in June 2006

The AtNFXL1 gene functions as a signaling component of the type A trichothecene-dependent response

scientific article

The defense response in Arabidopsis thaliana against Fusarium sporotrichioides.

scientific article published on 30 October 2012

The flexible C-terminal region of Aspergillus terreus blasticidin S deaminase: identification of its functional roles with deletion enzymes.

scientific article published in January 2002

The mystery of the trichothecene 3-O-acetyltransferase gene. Analysis of the region around Tri101 and characterization of its homologue from Fusarium sporotrichioides

scientific article published in September 1998

The secreted antifungal protein thionin 2.4 in Arabidopsis thaliana suppresses the toxicity of a fungal fruit body lectin from Fusarium graminearum

scientific article

The trichothecene biosynthesis gene cluster of Fusarium graminearum F15 contains a limited number of essential pathway genes and expressed non-essential genes

scientific article published in March 2003

The trichothecene biosynthesis regulatory gene from the type B producer Fusarium strains: sequence of Tri6 and its expression in Escherichia coli

scientific article published in November 1999

Transgenic rice plants expressing trichothecene 3-O-acetyltransferase show resistance to the Fusarium phytotoxin deoxynivalenol

scientific article published on 10 October 2006

Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101.

scientific article published in January 1998

List of works by Makoto Kimura

2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA) inhibits trichothecene production by Fusarium graminearum through suppression of Tri6 expression.

4-O-Glucosylation of Trichothecenes by Fusarium Species: A Phase II Xenobiotic Metabolism for t-Type Trichothecene Producers

4-O-acetylation and 3-O-acetylation of trichothecenes by trichothecene 15-O-acetyltransferase encoded by Fusarium Tri3.

A fluorescent antibiotic resistance marker for rapid production of transgenic rice plants

A model transgenic cereal plant with detoxification activity for the estrogenic mycotoxin zearalenone

A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

A screening system for inhibitors of trichothecene biosynthesis: hydroxylation of trichodiene as a target

A wheat xylanase inhibitor gene, Xip-I, but not Taxi-I, is significantly induced by biotic and abiotic signals that trigger plant defense.

ATF-1 transcription factor regulates the expression of ccg-1 and cat-1 genes in response to fludioxonil under OS-2 MAP kinase in Neurospora crassa

Acetyltransferase activity in Pseudomonas sp. capable of acetylating the C-4 hydroxyl group of nivalenol-type trichothecenes

AtNFXL1, an Arabidopsis homologue of the human transcription factor NF-X1, functions as a negative regulator of the trichothecene phytotoxin-induced defense response.

Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells.

Characterization of genes encoding metal tolerance proteins isolated from Nicotiana glauca and Nicotiana tabacum.

Characterization of the acivicin effects on trichothecene production by Fusarium graminearum species complex.

Circadian Rhythm of Circumnutation in Inflorescence Stems of Arabidopsis

Cloning and characterization of genes specifically expressed during infection stages in the rice blast fungus.

Cloning and characterization of six highly similar endo-1,3-beta-glucanase genes in hexaploid wheat

Cloning of the blasticidin S deaminase gene (BSD) from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae

Comparison of the paralogous transcription factors AraR and XlnR in Aspergillus oryzae.

Concordant evolution of trichothecene 3-O-acetyltransferase and an rDNA species phylogeny of trichothecene-producing and non-producing fusaria and other ascomycetous fungi

Conferring cadmium resistance to mature tobacco plants through metal-adsorbing particles of tomato mosaic virus vector

Copper elicits an increase in cytosolic free calcium in cultured tobacco cells

Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc

Crystallization and preliminary X-ray diffraction studies of blasticidin S deaminase from Aspergillus terreus

Development of a simultaneous liquid chromatography/tandem mass spectrometric method for the determination of type B trichothecenes, their derivatives, and precursors in wheat

Effect of disrupting the trichothecene efflux pump encoded by FgTri12 in the nivalenol chemotype of Fusarium graminearum

Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi

Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene.

Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin

Features ofTri101, the Trichothecene 3-O-Acetyltransferase Gene, Related to the Self-defense Mechanism inFusarium graminearum

Fusarium Tri4 encodes a key multifunctional cytochrome P450 monooxygenase for four consecutive oxygenation steps in trichothecene biosynthesis.

Fusarium phytotoxin trichothecenes have an elicitor-like activity in Arabidopsis thaliana, but the activity differed significantly among their molecular species

Genetically engineered Fusarium as a tool to evaluate the effects of environmental factors on initiation of trichothecene biosynthesis

Genotyping of benzimidazole-resistant and dicarboximide-resistant mutations in Botrytis cinerea using real-time polymerase chain reaction assays

Hydroxylations of trichothecene rings in the biosynthesis of Fusarium trichothecenes: evolution of alternative pathways in the nivalenol chemotype.

Identification and Characterization of Small Molecule Compounds That Modulate Trichothecene Production by Fusarium graminearum

Identification and characterization of an inhibitor of trichothecene 3-O-acetyltransferase, TRI101, by the chemical array approach

Identification of OS-2 MAP kinase-dependent genes induced in response to osmotic stress, antifungal agent fludioxonil, and heat shock in Neurospora crassa.

Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein.

Identification of amino acids negatively affecting Fusarium trichothecene biosynthesis

Identification of multiple highly similar XIP-type xylanase inhibitor genes in hexaploid wheat

Impact of nitrogen metabolism-associated culture pH changes on regulation of Fusarium trichothecene biosynthesis: revision of roles of polyamine agmatine and transcription factor AreA

Increased metabolite production by deletion of an HDA1-type histone deacetylase in the phytopathogenic fungi, Magnaporthe oryzae (Pyricularia oryzae) and Fusarium asiaticum.

Inhibition of Fusarium trichothecene biosynthesis by yeast extract components extractable with ethyl acetate

Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae

Involvement of an SRF-MADS protein McmA in regulation of extracellular enzyme production and asexual/sexual development in Aspergillus nidulans

Involvement of the osmosensor histidine kinase and osmotic stress-activated protein kinases in the regulation of secondary metabolism in Fusarium graminearum.

L-Threonine and its analogue added to autoclaved solid medium suppress trichothecene production by Fusarium graminearum.

McmA-dependent and -independent regulatory systems governing expression of ClrB-regulated cellulase and hemicellulase genes in Aspergillus nidulans

Metabolism of zearalenone by genetically modified organisms expressing the detoxification gene from Clonostachys rosea.

Microbial toxins in plant-pathogen interactions: Biosynthesis, resistance mechanisms, and significance

Multilocus genotyping and molecular phylogenetics resolve a novel head blight pathogen within the Fusarium graminearum species complex from Ethiopia.

New TAXI-type xylanase inhibitor genes are inducible by pathogens and wounding in hexaploid wheat

Nicotinamide Mononucleotide Potentiates Resistance to Biotrophic Invasion of Fungal Pathogens in Barley

Nicotinamide mononucleotide and related metabolites induce disease resistance against fungal phytopathogens in Arabidopsis and barley.

Oligosaccharides containing an α-(1→2) (glucosyl/xylosyl)-fructosyl linkage as inducer molecules of trichothecene biosynthesis for Fusarium graminearum.

Pattern of N gene-mediated systemic hypersensitive response and turnover of viral replicase protein in tobacco

Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana

Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum.

Proteome analysis of wheat lemma.

Re-examination of genetic and nutritional factors related to trichothecene biosynthesis in Fusarium graminearum.

Reduced Toxicity of Trichothecenes, Isotrichodermol, and Deoxynivalenol, by Transgenic Expression of the Tri101 3-O-Acetyltransferase Gene in Cultured Mammalian FM3A Cells

Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene

Regulation of genes encoding cellulolytic enzymes by Pal-PacC signaling in Aspergillus nidulans

Roles of putative His-to-Asp signaling modules HPT-1 and RRG-2, on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa

Screening of putative oxygenase genes in the Fusarium graminearum genome sequence database for their role in trichothecene biosynthesis

Site-specific DNA double-strand break generated by I-SceI endonuclease enhances ectopic homologous recombination in Pyricularia oryzae

Spiroethers of German chamomile inhibit production of aflatoxin G and trichothecene mycotoxin by inhibiting cytochrome P450 monooxygenases involved in their biosynthesis.

Substrate specificities of Fusarium biosynthetic enzymes explain the genetic basis of a mixed chemotype producing both deoxynivalenol and nivalenol-type trichothecenes

The 1.48 A resolution crystal structure of the homotetrameric cytidine deaminase from mouse.

The AtNFXL1 gene functions as a signaling component of the type A trichothecene-dependent response

The defense response in Arabidopsis thaliana against Fusarium sporotrichioides.

The flexible C-terminal region of Aspergillus terreus blasticidin S deaminase: identification of its functional roles with deletion enzymes.

The mystery of the trichothecene 3-O-acetyltransferase gene. Analysis of the region around Tri101 and characterization of its homologue from Fusarium sporotrichioides

The secreted antifungal protein thionin 2.4 in Arabidopsis thaliana suppresses the toxicity of a fungal fruit body lectin from Fusarium graminearum

The trichothecene biosynthesis gene cluster of Fusarium graminearum F15 contains a limited number of essential pathway genes and expressed non-essential genes

The trichothecene biosynthesis regulatory gene from the type B producer Fusarium strains: sequence of Tri6 and its expression in Escherichia coli

Transgenic rice plants expressing trichothecene 3-O-acetyltransferase show resistance to the Fusarium phytotoxin deoxynivalenol

Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101.