List of works - Dimitris Athineos

A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing

scientific article published on 12 July 2019

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

scientific article

Activation by c-Myc of transcription by RNA polymerases I, II and III.

scientific article

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation

scientific article

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver

scholarly article

CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma

scientific article published on 16 August 2016

Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

scientific article published in 2024

Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss

scientific article published on 24 August 2010

Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma

scientific article published on 17 March 2010

Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

scientific article published on August 2010

Formate induces a metabolic switch in nucleotide and energy metabolism

scientific article published on 04 May 2020

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

scientific article

In-Depth Proteomics Identifies a Role for Autophagy in Controlling Reactive Oxygen Species Mediated Endothelial Permeability.

scientific article published in June 2016

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

scientific article published on 25 August 2016

Increased formate overflow is a hallmark of oxidative cancer.

scientific article

LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

scientific article published on 06 May 2010

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death

scientific article

Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest

scientific article

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

scientific article

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

scientific article

Myc deletion rescues Apc deficiency in the small intestine

scientific journal article

Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine.

scientific article

Polyamine pathway activity promotes cysteine essentiality in cancer cells

scientific article published on 03 August 2020

RIPK3 promotes adenovirus type 5 activity

scientific article

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

scientific article published on 09 May 2013

RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome

scientific article published on 10 March 2020

Regulation of TFIIIB during F9 cell differentiation

scientific article

Serine one-carbon catabolism with formate overflow

scientific article published on 28 October 2016

TIGAR is required for efficient intestinal regeneration and tumorigenesis

scientific journal article

The in vivo function of the p53 target gene TIGAR.

scientific article

The role of MIZ-1 in MYC-dependent tumorigenesis

scientific article

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.

scientific article

Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

scientific article published on 12 September 2016

List of works by Dimitris Athineos

A Unique Panel of Patient-Derived Cutaneous Squamous Cell Carcinoma Cell Lines Provides a Preclinical Pathway for Therapeutic Testing

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

Activation by c-Myc of transcription by RNA polymerases I, II and III.

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver

CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma

Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function

Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss

Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma

Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.

Formate induces a metabolic switch in nucleotide and energy metabolism

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

In-Depth Proteomics Identifies a Role for Autophagy in Controlling Reactive Oxygen Species Mediated Endothelial Permeability.

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Increased formate overflow is a hallmark of oxidative cancer.

LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death

Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest

Modulating the therapeutic response of tumours to dietary serine and glycine starvation

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

Myc deletion rescues Apc deficiency in the small intestine

Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine.

Polyamine pathway activity promotes cysteine essentiality in cancer cells

RIPK3 promotes adenovirus type 5 activity

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome

Regulation of TFIIIB during F9 cell differentiation

Serine one-carbon catabolism with formate overflow

TIGAR is required for efficient intestinal regeneration and tumorigenesis

The in vivo function of the p53 target gene TIGAR.

The role of MIZ-1 in MYC-dependent tumorigenesis

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium.

Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers