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List of works by Mario Delgado

A novel mechanism for immunosuppression: from neuropeptides to regulatory T cells.

scientific article published on 10 October 2006

A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells

scientific article published in 2024

Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses

scientific article published on 27 November 2008

Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis

scientific article published on 25 May 2012

Adrenomedullin protects from experimental arthritis by down-regulating inflammation and Th1 response and inducing regulatory T cells.

scientific article published on January 2007

Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases.

scientific article published on 17 January 2018

Allogeneic Adipose-Derived Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Regulating Self-Reactive T Cell Responses and Dendritic Cell Function

scientific article published on 30 January 2017

Analgesic effect of the neuropeptide cortistatin in murine models of arthritic inflammatory pain

scientific article published in May 2013

Analysis of a GT microsatellite in the promoter of the foxp3/scurfin gene in autoimmune diseases.

scientific article

Anti-inflammatory neuropeptide receptors: new therapeutic targets for immune disorders?

scientific article published on 3 August 2007

Anti-inflammatory neuropeptides: a new class of endogenous immunoregulatory agents

scientific article published on 14 June 2008

Anti-inflammatory properties of the type 1 and type 2 vasoactive intestinal peptide receptors: role in lethal endotoxic shock

scientific article published on 01 November 2000

Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor.

scientific article

Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease.

scientific article

Bone marrow mesenchymal stem/stromal cells from risk-stratified acute myeloid leukemia patients are anti-inflammatory in preclinical models of hematopoietic reconstitution and severe colitis

scientific article published on 20 September 2018

Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.

scientific article

Characterization of gene expression of VIP and VIP1-receptor in rat peritoneal lymphocytes and macrophages

scientific article published on 01 April 1996

Cortistatin attenuates inflammatory pain via spinal and peripheral actions.

scientific article

Cortistatin inhibits migration and proliferation of human vascular smooth muscle cells and decreases neointimal formation on carotid artery ligation.

scientific article published on 17 April 2013

Cortistatin reduces atherosclerosis in hyperlipidemic ApoE-deficient mice and the formation of foam cells

scientific article

Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia.

scientific article published on 21 February 2006

Cortistatin, an antiinflammatory peptide with therapeutic action in inflammatory bowel disease.

scholarly article

Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs.

scientific article

Differential VIP and VIP1 receptor gene expression in rat thymocyte subsets

scientific article published on 01 January 1996

Differential expression of vasoactive intestinal peptide receptors 1 and 2 (VIP-R1 and VIP-R2) mRNA in murine lymphocytes.

scientific article published on August 1996

Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.

scientific article published on February 2011

Expression of vasoactive intestinal peptide in lymphocytes: a possible endogenous role in the regulation of the immune system.

scientific article published on January 1996

Functional characterization and mRNA expression of pituitary adenylate cyclase activating polypeptide (PACAP) type I receptors in rat peritoneal macrophages

scientific article published on 01 December 1997

Gene expression of VIP receptor in rat lymphocytes

scientific article published on 01 September 1994

Generating tolerogenic dendritic cells with neuropeptides.

scientific article published in May 2009

Genetic association of vasoactive intestinal peptide receptor with rheumatoid arthritis: Altered expression and signal in immune cells

scholarly article by Mario Delgado et al published 27 March 2008 in Arthritis and Rheumatism

Ghrelin and adipose-derived mesenchymal stromal cells improve nerve regeneration in a rat model of epsilon-caprolactone conduit reconstruction

scientific article published on 30 September 2016

Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants

scientific article

Homologous and heterologous in vitro regulation of pig pituitary somatostatin receptor subtypes, sst1, sst2 and sst5 mRNA.

scientific article published in April 2004

Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis

scientific article published on 01 January 2010

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

scientific article published on 09 January 2009

Human amnion favours tissue repair by inducing the M1-to-M2 switch and enhancing M2 macrophage features.

scientific article published on 11 July 2016

Human bone marrow stromal cells lose immunosuppressive and anti-inflammatory properties upon oncogenic transformation

scientific article

Immunology of VIP: a review and therapeutical perspectives.

scientific article

Immunotherapy for neurological diseases

scientific article published on 04 June 2008

In vivo delivery of lentiviral vectors expressing vasoactive intestinal peptide complementary DNA as gene therapy for collagen-induced arthritis.

scholarly article

Inhaled vasoactive intestinal peptide exerts immunoregulatory effects in sarcoidosis.

scientific article

Inhibition of endotoxin-induced macrophage chemokine production by VIP and PACAP in vitro and in vivo

scientific article

Inhibitory neuropeptide receptors on macrophages

scientific article

LABCG2, a new ABC transporter implicated in phosphatidylserine exposure, is involved in the infectivity and pathogenicity of Leishmania

scientific article

Lulling immunity, pain, and stress to sleep with cortistatin.

scientific article published on 07 May 2015

Lymphoid cell subpopulations containing vasoactive intestinal peptide in the rat

scientific article published on 01 January 1994

Mesenchymal stem cells expressing vasoactive intestinal peptide ameliorate symptoms in a model of chronic multiple sclerosis

scientific article

Mesenchymal stem cells induce the ramification of microglia via the small RhoGTPases Cdc42 and Rac1.

scientific article published on 3 July 2014

Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells

scientific article published on 04 December 2007

Murine T-lymphocytes express vasoactive intestinal peptide receptor 1 (VIP-R1) mRNA.

scientific article published in August 1996

N-acetyl-L-cysteine combined with mesalamine in the treatment of ulcerative colitis: randomized, placebo-controlled pilot study

scientific article published on May 2008

NPSR1 gene is associated with reduced risk of rheumatoid arthritis

scientific article published in May 2012

Neuropeptides as therapeutic approach to autoimmune diseases.

scientific article published on January 2010

Neuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death.

scientific article published on 5 December 2008

Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1.

scientific article published in April 2008

Neuropeptides: keeping the balance between pathogen immunity and immune tolerance

scientific article

Osteoarticular Expression of Musashi-1 in an Experimental Model of Arthritis

scientific article published on 3 May 2015

Peripheral nerve reconstruction with epsilon-caprolactone conduits seeded with vasoactive intestinal peptide gene-transfected mesenchymal stem cells in a rat model

scientific article published on 15 July 2014

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) stimulates rat peritoneal macrophage functions

scientific article published on 01 January 1996

Pituitary adenylate cyclase-activating polypeptide (PACAP38) modulates lymphocyte and macrophage functions: stimulation of adherence and opposite effect on mobility

scientific article published on 01 December 1996

Pituitary adenylate cyclase-activating polypeptides (PACAP27 and PACAP38) inhibit the mobility of murine thymocytes and splenic lymphocytes: comparison with VIP and implication of cAMP

scientific article published on 01 November 1995

Pituitary adenylate-cyclase-activating polypeptide expression in the immune system

scientific article published in January 2002

Potential applications of vasoactive intestinal Peptide-based therapies on transplantation

scientific article published on December 2012

Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation

scientific article

Proinflammatory signals are insufficient to drive definitive hematopoietic specification of human HSCs in vitro.

scientific article published on 27 September 2016

Protective role for plasmid DNA-mediated VIP gene transfer in non-obese diabetic mice.

scientific article published in July 2006

Receptors and transcriptional factors involved in the anti-inflammatory activity of VIP and PACAP

scientific article published on 01 January 2000

Regulation of VIP production and secretion by murine lymphocytes

scientific article published on 01 January 1999

Requirement of IFN-gamma-mediated indoleamine 2,3-dioxygenase expression in the modulation of lymphocyte proliferation by human adipose-derived stem cells

scientific article published in October 2009

Research progress in the stimulatory inputs regulating growth hormone (GH) secretion.

scientific article

Role of Cortistatin in the Stressed Immune System

scientific article published on 28 February 2017

Shedding of membrane-bound CD14 from lipopolysaccharide-stimulated macrophages by vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide

scientific article published on 01 September 1999

Signaling mechanisms of vasoactive intestinal peptide in inflammatory conditions.

scientific article published on September 2006

Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38

scientific article published on 3 March 2014

Stimulation by vasoactive intestinal peptide (VIP) of phagocytic function in rat macrophages. Protein kinase C involvement

scientific article published on 01 November 1993

TH2 lymphocytes secrete functional VIP upon antigen stimulation

scientific article published in October 2001

The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia

scientific article published on 15 December 2018

The many faces of VIP in neuroimmunology: a cytokine rather a neuropeptide?

scientific article published on 01 September 2004

The neuropeptide cortistatin attenuates experimental autoimmune myocarditis via inhibition of cardiomyogenic T cell-driven inflammatory responses.

scientific article published on 6 December 2016

The significance of vasoactive intestinal peptide in immunomodulation

scientific article

Therapeutic action of ghrelin in a mouse model of colitis.

scientific article

Therapeutic application of mesenchymal stromal cells in murine models of inflammatory bowel disease

scientific article published on 01 January 2014

Therapeutic effect of a poly(ADP-ribose) polymerase-1 inhibitor on experimental arthritis by downregulating inflammation and Th1 response

scientific article

Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses.

scientific article published on 6 December 2006

Therapeutic effect of human amniotic membrane-derived cells on experimental arthritis and other inflammatory disorders

scientific article published on 01 February 2014

Therapeutic effect of the immunomodulatory drug lenalidomide, but not pomalidomide, in experimental models of rheumatoid arthritis and inflammatory bowel disease.

scientific article published on 3 February 2017

Therapeutic effect of urocortin on collagen-induced arthritis by down-regulation of inflammatory and Th1 responses and induction of regulatory T cells

scientific article published on 01 February 2007

Therapeutic effect of vasoactive intestinal peptide on experimental autoimmune encephalomyelitis: down-regulation of inflammatory and autoimmune responses

scientific article

Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid mice model of Crohn's disease

scientific article published in April 2003

Therapeutic efficacy of stable analogues of vasoactive intestinal peptide against pathogens.

scientific article

Therapeutic treatment of experimental colitis with regulatory dendritic cells generated with vasoactive intestinal peptide

scientific article published on 15 October 2006

Therapeutical approaches of vasoactive intestinal peptide as a pleiotropic immunomodulator.

scientific article

Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells

scientific article published on 01 April 2009

Tuning immune tolerance with vasoactive intestinal peptide: a new therapeutic approach for immune disorders

scientific article published on 20 April 2007

VIP and PACAP enhance IL-6 release and mRNA levels in resting peritoneal macrophages: in vitro and in vivo studies.

scientific article published in May 1998

VIP and PACAP enhance the in vivo generation of memory TH2 cells by inhibiting peripheral deletion of antigen-specific effectors

scientific article

VIP and PACAP induce shift to a Th2 response by upregulating B7.2 expression

scientific article published on 01 January 2000

VIP and PACAP inhibit IL-12 production in LPS-stimulated macrophages. Subsequent effect on IFNgamma synthesis by T cells

scientific article published on 01 May 1999

VIP and PACAP inhibit activation induced apoptosis in T lymphocytes.

scientific article

VIP gene expression in rat thymus and spleen

scientific article published on 01 December 1993

VIP modulation of immune cell functions.

scientific article published on January 1996

VIP prevents experimental multiple sclerosis by downregulating both inflammatory and autoimmune components of the disease

scientific article published on 01 July 2006

VIP protects Th2 cells by downregulating granzyme B expression

scientific article published on 01 July 2006

VIP/PACAP oppositely affects immature and mature dendritic cell expression of CD80/CD86 and the stimulatory activity for CD4(+) T cells

scientific article published on 12 March 2004

VIP/PACAP preferentially attract Th2 effectors through differential regulation of chemokine production by dendritic cells.

scientific article

VIP: a very important peptide in T helper differentiation ⬇️

scientific article published on May 1, 2003

VIP: an agent with license to kill infective parasites

scientific article published in July 2006

Vasoactive Intestinal Peptide Ameliorates Acute Myocarditis and Atherosclerosis by Regulating Inflammatory and Autoimmune Responses

scientific article published on 18 April 2018

Vasoactive intestinal peptide (VIP) mRNA expression in rat T and B lymphocytes.

scientific article published on February 1994

Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit the MEKK1/MEK4/JNK signaling pathway in LPS-stimulated macrophages

scientific article published on 01 October 2000

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit CBP-NF-kappaB interaction in activated microglia.

scientific article

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia

scientific article

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit nuclear factor-kappa B-dependent gene activation at multiple levels in the human monocytic cell line THP-1.

scientific article

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit the MEKK1/MEK4/JNK signaling pathway in endotoxin-activated microglia

scientific article

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit the production of inflammatory mediators by activated microglia

scientific article published in January 2003

Vasoactive intestinal peptide and regulatory T-cell induction: a new mechanism and therapeutic potential for immune homeostasis

scientific article published on 27 April 2007

Vasoactive intestinal peptide family as a therapeutic target for Parkinson's disease.

scientific article

Vasoactive intestinal peptide generates CD4+CD25+ regulatory T cells in vivo

scientific article published on 04 October 2005

Vasoactive intestinal peptide generates CD4+CD25+ regulatory T cells in vivo: therapeutic applications in autoimmunity and transplantation

scientific article published on 01 July 2006

Vasoactive intestinal peptide generates human tolerogenic dendritic cells that induce CD4 and CD8 regulatory T cells.

scientific article published on 5 January 2006

Vasoactive intestinal peptide in thymus: synthesis, receptors and biological actions

scientific article published on 01 January 1999

Vasoactive intestinal peptide induces CD4+,CD25+ T regulatory cells with therapeutic effect in collagen-induced arthritis.

scientific article published on March 2006

Vasoactive intestinal peptide induces regulatory T cells during experimental autoimmune encephalomyelitis

scientific article published on 01 February 2006

Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders.

scientific article

Vasoactive intestinal peptide inhibits IL-8 production in human monocytes

scientific article published on 01 February 2003

Vasoactive intestinal peptide inhibits IL-8 production in human monocytes by downregulating nuclear factor kappaB-dependent transcriptional activity

scientific article published on 01 March 2003

Vasoactive intestinal peptide inhibits cyclooxygenase-2 expression in activated macrophages, microglia, and dendritic cells

scientific article published on 07 September 2007

Vasoactive intestinal peptide modulation of adherence and mobility in rat peritoneal lymphocytes and macrophages

scientific article published on 01 January 1994

Vasoactive intestinal peptide prevents activated microglia-induced neurodegeneration under inflammatory conditions: potential therapeutic role in brain trauma.

scientific article published on 15 August 2003

Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease

scientific article published on 01 May 2001

Vasoactive intestinal peptide protects against beta-amyloid-induced neurodegeneration by inhibiting microglia activation at multiple levels

scientific article published on 01 August 2008

Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions

scientific article

Vasoactive intestinal peptide: the dendritic cell --> regulatory T cell axis

scientific article published on 01 July 2006

Vasoactive intestinal polypeptide induces regulatory dendritic cells that prevent acute graft versus host disease and leukemia relapse after bone marrow transplantation.

scientific article published on July 2006

miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity

scientific article published on August 2014

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