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List of works by Jonathan T Brown

4-dimensional functional profiling in the convulsant-treated larval zebrafish brain.

scientific article published on 26 July 2017

A pharmacological investigation of the role of GLUK5-containing receptors in kainate-driven hippocampal gamma band oscillations

scientific article

A unified model of CA1/3 pyramidal cells: an investigation into excitability.

scientific article published on 29 September 2010

Activation of SK channels inhibits epileptiform bursting in hippocampal CA3 neurons.

scientific article published on 5 December 2005

Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons.

scientific article published on 26 January 2009

Age-Dependent Long-Term Potentiation Deficits in the Prefrontal Cortex of the Fmr1 Knockout Mouse Model of Fragile X Syndrome

scientific article published on 5 March 2015

Age-related changes to Na+ channel gating contribute to modified intrinsic neuronal excitability

scientific article published on 28 January 2012

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy.

scientific article

Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1

scientific article published on 19 May 2015

Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice

scientific article published on 14 October 2015

Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease.

scientific article published on 27 July 2011

Altered synaptic plasticity in the mossy fibre pathway of transgenic mice expressing mutant amyloid precursor protein ⬇️

scientific article published on November 1, 2010

Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1

scientific article

Characterization of altered intrinsic excitability in hippocampal CA1 pyramidal cells of the Aβ-overproducing PDAPP mouse.

scientific article published on 18 September 2013

Control of clustered action potential firing in a mathematical model of entorhinal cortex stellate cells.

scientific article published on 11 April 2018

Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry

scientific article published on 12 December 2017

Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia

scientific article published on 5 December 2014

Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system.

scientific article published on April 2014

Disruption of hippocampal-prefrontal cortex activity by dopamine D2R-dependent LTD of NMDAR transmission

scientific article

Domino-like transient dynamics at seizure onset in epilepsy

scientific article published on 28 September 2020

Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy.

scientific article

Forced cell cycle exit and modulation of GABAA, CREB, and GSK3β signaling promote functional maturation of induced pluripotent stem cell-derived neurons.

scientific article published on 30 December 2015

Frequency-dependent inhibition of antidromic hippocampal compound action potentials by anti-convulsants.

scientific article

Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro.

scientific article published in March 2005

Gabapentin is not a GABAB receptor agonist

scientific article published in December 2001

Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome

scientific article

Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein.

scientific article published on 20 July 2017

Improving and accelerating the differentiation and functional maturation of human stem cell-derived neurons: role of extracellular calcium and GABA.

scientific article published on 12 September 2016

In Vitro and In Vivo Recording of Local Field Potential Oscillations in Mouse Hippocampus

scientific article published on 01 September 2012

In vitro characterization of cell-level neurophysiological diversity in the rostral nucleus reuniens of adult mice.

scientific article published on 11 March 2017

Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices.

scientific article published in April 2006

Initiation and slow propagation of epileptiform activity from ventral to dorsal medial entorhinal cortex is constrained by an inhibitory gradient.

scientific article published on 31 March 2018

Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide

scientific article

KCNQ/Kv7 channel regulation of hippocampal gamma-frequency firing in the absence of synaptic transmission.

scientific article published on 8 February 2006

Low concentrations of the solvent dimethyl sulphoxide alter intrinsic excitability properties of cortical and hippocampal pyramidal cells

scientific article

Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit

scientific article published in June 2005

Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices of GABAB1 receptor subunit knockout mice.

scientific article published in December 2003

Metabotropic glutamate receptor 1 activity generates persistent, N-methyl-D-aspartate receptor-dependent depression of hippocampal pyramidal cell excitability.

scientific article published on 29 May 2009

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

scientific article

Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease.

scientific article

Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy.

scientific article published on 26 February 2018

Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1

scientific article published on April 2014

Preferential assembly of heteromeric small conductance calcium-activated potassium channels

scientific article published on 25 November 2014

Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model

scientific article

Sensitivity analysis to explain the excitability in a pyramidal neuron with application to Alzheimer’s disease

scientific article

Sex-associated differences in excitability within the bed nucleus of the stria terminalis are reflective of cell-type

scientific article published on 19 December 2018

Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease.

scientific article published in April 2013

Synaptic activation of GABA(B) receptors regulates neuronal network activity and entrainment.

scientific article

Synaptic activation of mGluR1 generates persistent depression of a fast after-depolarizing potential in CA3 pyramidal neurons.

scientific article

Synaptic transmission and synchronous activity is disrupted in hippocampal slices taken from aged TAS10 mice

scientific article published in January 2005

TRPM2 is elevated in the tMCAO stroke model, transcriptionally regulated, and functionally expressed in C13 microglia.

scientific article published on January 2006

The GABAB2 subunit is critical for the trafficking and function of native GABAB receptors

scientific article published on 01 October 2004

The functional neurophysiology of the amyloid precursor protein (APP) processing pathway

scientific article published on 16 February 2010

The induction of long-term plasticity of non-synaptic, synchronized activity by the activation of group I mGluRs.

scientific article published on 28 May 2008

Vesicular release of glutamate utilizes the proton gradient between the vesicle and synaptic cleft.

scientific article

Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596 ⬇️

scientific article published on December 27, 2011

Voltage- and temperature-dependent gating of heterologously expressed channelrhodopsin-2

scientific article published on 4 August 2010

β3-Adrenergic receptor-dependent modulation of the medium afterhyperpolarization in rat hippocampal CA1 pyramidal neurons

scientific article published on 09 January 2019

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