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List of works by Bogdan Fedeles

A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo

scientific article (publication date: 2014)

APP processing and synaptic plasticity in presenilin-1 conditional knockout mice

scientific journal article

An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity

scientific article published on 28 December 2017

Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target

scientific article

Design, synthesis, and evaluation of estradiol-linked genotoxicants as anti-cancer agents

scientific article

Early detection of the aflatoxin B1 mutational fingerprint: A diagnostic tool for liver cancer

scientific article

Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver

scientific article

G-quadruplex-forming promoter sequences enable transcriptional activation in response to oxidative stress.

scientific article published on 6 March 2017

Impact of DNA lesion repair, replication and formation on the mutational spectra of environmental carcinogens: Aflatoxin B as a case study

scientific article published on 25 August 2018

Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer

scientific article

Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkB

scientific article

Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.

scientific article

Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo

scientific article published on 2 April 2015

Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions

scientific article

Removal of N-alkyl modifications from N(2)-alkylguanine and N(4)-alkylcytosine in DNA by the adaptive response protein AlkB

scientific article published on 10 July 2013

Role of tautomerism in RNA biochemistry

scientific article

Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine

scientific article

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

scientific article

Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity

scientific article