List of works - Yves Poumay

A simple reconstructed human epidermis: preparation of the culture model and utilization in in vitro studies.

scientific article

Analysis of interleukin-1alpha (IL-1alpha) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization

scientific article

Atopic Dermatitis Studies through In Vitro Models.

scientific article published on 24 July 2017

Basal detachment of the epidermis using dispase: tissue spatial organization and fate of integrin alpha 6 beta 4 and hemidesmosomes.

scientific article

Ca(2+)/calmodulin-dependent protein kinase (CaM-kinase) inhibitor KN-62 suppresses the activity of mitogen-activated protein kinase (MAPK), c-myc activation and human keratinocyte proliferation

scientific article

Candidate housekeeping genes require evaluation before their selection for studies of human epidermal keratinocytes

scientific article published on 21 August 2008

Cell density and culture factors regulate keratinocyte commitment to differentiation and expression of suprabasal K1/K10 keratins

scientific article published in February 1995

Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38.

scientific article published in September 2004

Development of a chitosan nanofibrillar scaffold for skin repair and regeneration

scientific article published on 01 August 2011

Differential expression and release of cytokines by an in vitro reconstructed human epidermis following exposure to skin irritant and sensitizing chemicals

scientific article published on 01 December 1999

Differentiation-dependent alternative splicing and expression of the extracellular matrix protein 1 gene in human keratinocytes.

scientific article

Dual role of protein kinase C on mitogen-activated protein kinase activation and human keratinocyte proliferation.

scientific article published in August 2002

Effects of the cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) on the physiology of cultured human keratinocytes

scientific article published on 01 September 2005

Epidermal morphogenesis during progressive in vitro 3D reconstruction at the air-liquid interface

scientific article published on 01 November 2012

Epidermal reference genes at the forefront of data interpretation

scientific article

Erratum to: The activation of cultured keratinocytes by cholesterol depletion during reconstruction of a human epidermis is reminiscent of monolayer cultures

scientific article published on 18 June 2016

Expression of lysosome-associated membrane protein 1 (Lamp-1) and galectins in human keratinocytes is regulated by differentiation

scientific article published on 22 April 2006

Functional redundancy of extracellular matrix protein 1 in epidermal differentiation.

scientific article

HB-EGF synthesis and release induced by cholesterol depletion of human epidermal keratinocytes is controlled by extracellular ATP and involves both p38 and ERK1/2 signaling pathways

scientific article published in June 2011

HB-EGF, the growth factor that accelerates keratinocyte migration, but slows proliferation

scientific article published on 01 September 2012

Heparin-binding EGF-like growth factor is induced by disruption of lipid rafts and oxidative stress in keratinocytes and participates in the epidermal response to cutaneous wounds

scientific article published on 11 October 2007

High TMEM45A expression is correlated to epidermal keratinization.

scientific article published in May 2014

High-cell-density phorbol ester and retinoic acid upregulate involucrin and downregulate suprabasal keratin 10 in autocrine cultures of human epidermal keratinocytes

scientific article published on 01 August 1999

Human EGF receptor (HER) family and heregulin members are differentially expressed in epidermal keratinocytes and modulate differentiation

scientific article published in December 2001

Human epidermal keratinocytes upregulate expression of the prolactin receptor after the onset of terminal differentiation, but do not respond to prolactin

scientific article published on 01 April 1999

Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation

scientific article published on December 2015

Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin is driven by a balance of hyaluronan synthases 1 and 3.

scientific article

Hyaluronidase-1 Is Mainly Functional in the Upper Granular Layer, Close to the Epidermal Barrier

scientific article published on 27 July 2015

In vitro models of dermatophyte infection to investigate epidermal barrier alterations

scientific article published on 01 August 2018

In vitro reconstruction of epidermis from primary Darier's disease keratinocytes replicates the histopathological phenotype.

scientific article

Incubation of endothelial cells in a superoxide-generating system: impaired low-density lipoprotein receptor-mediated endocytosis.

scientific article published on August 1988

Inhibition of Akt signaling by exclusion from lipid rafts in normal and transformed epidermal keratinocytes

scientific article

Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation

scientific article

Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation.

scientific article

Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation

scientific article published on 13 June 2014

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

scientific journal article

Lipid rafts and the oxidative stress hypothesis

scientific article published on 7 January 2010

Meaning of relative gene expression in multilayered cultures of epidermal keratinocytes.

scientific article published on October 2014

Methyl-β-cyclodextrin concurs with interleukin (IL)-4, IL-13 and IL-25 to induce alterations reminiscent of atopic dermatitis in reconstructed human epidermis

scientific article

Methyl-β-cyclodextrin treatment combined to incubation with interleukin-4 reproduces major features of atopic dermatitis in a 3D-culture model.

scientific article published on 11 November 2016

Microscopy: access to the bigger picture in histology

scientific article published in March 2015

Modeling dermatophytosis in reconstructed human epidermis: A new tool to study infection mechanisms and to test antifungal agents.

scientific article

Modelling atopic dermatitis during the morphogenetic process involved in reconstruction of a human epidermis

scientific article published on October 2016

Modelling the human epidermis in vitro: tools for basic and applied research

scientific article published on 28 October 2006

Non-senescent keratinocytes organize in plasma membrane submicrometric lipid domains enriched in sphingomyelin and involved in re-epithelialization

scientific article

Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.

scientific article published on 10 June 2013

Polysaccharide-coated PCL nanofibers for wound dressing applications.

scientific article published on 29 September 2014

Preparation and characterizations of EGDE crosslinked chitosan electrospun membranes.

scientific article published in January 2015

Processing and characterization of the low density lipoprotein receptor in the human colonic carcinoma cell subclone HT29-18: a potential pathway for delivering therapeutic drugs and genes

scientific article published on December 1, 1992

Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor

scientific article (publication date: 3 May 2010)

Reconstruction of normal and pathological human epidermis on polycarbonate filter

scientific article published on 01 January 2014

Responses of Reconstructed Human Epidermis to Trichophyton rubrum Infection and Impairment of Infection by the Inhibitor PD169316

scientific article published on 12 April 2019

Studies of cell signaling in a reconstructed human epidermis exposed to sensitizers: IL-8 synthesis and release depend on EGFR activation

scientific article published on 22 January 2012

Study of epidermal differentiation in human keratinocytes cultured in autocrine conditions.

scientific article

TMEM45A Is Dispensable for Epidermal Morphogenesis, Keratinization and Barrier Formation

scientific article published on 19 January 2016

The CYP26 inhibitor R115866 potentiates the effects of all-trans retinoic acid on cultured human epidermal keratinocytes

scientific article

The activation of cultured keratinocytes by cholesterol depletion during reconstruction of a human epidermis is reminiscent of monolayer cultures.

scientific article

The dumb ErbB receptor helps healing

scientific article published on 01 May 2007

The inhibition of the expression of the small Rho GTPase Rac1 induces differentiation with no effect on cell proliferation in growing human adult keratinocytes

scientific article published on 01 February 2008

The small Rho GTPase Rac1 controls normal human dermal fibroblasts proliferation with phosphorylation of the oncoprotein c-myc

scientific article published on 08 June 2007

Transcriptional profiling after lipid raft disruption in keratinocytes identifies critical mediators of atopic dermatitis pathways.

scientific article

Ultrastructural morphology of the male and female genital tracts of Psoroptes spp. (Acari: Astigmata: Psoroptidae).

scientific article published in January 2005

Utilization of human cultured epidermal keratinocytes: irreversibility of the inhibition of proliferation induced in stored detached cultures

scientific article published on 01 June 1991

p38 MAPK-regulated EGFR internalization takes place in keratinocyte monolayer during stress conditions

scientific article published on 29 December 2009

List of works by Yves Poumay

A simple reconstructed human epidermis: preparation of the culture model and utilization in in vitro studies.

Analysis of interleukin-1alpha (IL-1alpha) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization

Atopic Dermatitis Studies through In Vitro Models.

Basal detachment of the epidermis using dispase: tissue spatial organization and fate of integrin alpha 6 beta 4 and hemidesmosomes.

Ca(2+)/calmodulin-dependent protein kinase (CaM-kinase) inhibitor KN-62 suppresses the activity of mitogen-activated protein kinase (MAPK), c-myc activation and human keratinocyte proliferation

Candidate housekeeping genes require evaluation before their selection for studies of human epidermal keratinocytes

Cell density and culture factors regulate keratinocyte commitment to differentiation and expression of suprabasal K1/K10 keratins

Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38.

Development of a chitosan nanofibrillar scaffold for skin repair and regeneration

Differential expression and release of cytokines by an in vitro reconstructed human epidermis following exposure to skin irritant and sensitizing chemicals

Differentiation-dependent alternative splicing and expression of the extracellular matrix protein 1 gene in human keratinocytes.

Dual role of protein kinase C on mitogen-activated protein kinase activation and human keratinocyte proliferation.

Effects of the cyclin-dependent kinase inhibitor CYC202 (R-roscovitine) on the physiology of cultured human keratinocytes

Epidermal morphogenesis during progressive in vitro 3D reconstruction at the air-liquid interface

Epidermal reference genes at the forefront of data interpretation

Erratum to: The activation of cultured keratinocytes by cholesterol depletion during reconstruction of a human epidermis is reminiscent of monolayer cultures

Expression of lysosome-associated membrane protein 1 (Lamp-1) and galectins in human keratinocytes is regulated by differentiation

Functional redundancy of extracellular matrix protein 1 in epidermal differentiation.

HB-EGF synthesis and release induced by cholesterol depletion of human epidermal keratinocytes is controlled by extracellular ATP and involves both p38 and ERK1/2 signaling pathways

HB-EGF, the growth factor that accelerates keratinocyte migration, but slows proliferation

Heparin-binding EGF-like growth factor is induced by disruption of lipid rafts and oxidative stress in keratinocytes and participates in the epidermal response to cutaneous wounds

High TMEM45A expression is correlated to epidermal keratinization.

High-cell-density phorbol ester and retinoic acid upregulate involucrin and downregulate suprabasal keratin 10 in autocrine cultures of human epidermal keratinocytes

Human EGF receptor (HER) family and heregulin members are differentially expressed in epidermal keratinocytes and modulate differentiation

Human epidermal keratinocytes upregulate expression of the prolactin receptor after the onset of terminal differentiation, but do not respond to prolactin

Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation

Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin is driven by a balance of hyaluronan synthases 1 and 3.

Hyaluronidase-1 Is Mainly Functional in the Upper Granular Layer, Close to the Epidermal Barrier

In vitro models of dermatophyte infection to investigate epidermal barrier alterations

In vitro reconstruction of epidermis from primary Darier's disease keratinocytes replicates the histopathological phenotype.

Incubation of endothelial cells in a superoxide-generating system: impaired low-density lipoprotein receptor-mediated endocytosis.

Inhibition of Akt signaling by exclusion from lipid rafts in normal and transformed epidermal keratinocytes

Internalization of EGF receptor following lipid rafts disruption in keratinocytes is delayed and dependent on p38 MAPK activation

Knockdown of PKD1 in normal human epidermal keratinocytes increases mRNA expression of keratin 10 and involucrin: early markers of keratinocyte differentiation.

Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

Lipid rafts and the oxidative stress hypothesis

Meaning of relative gene expression in multilayered cultures of epidermal keratinocytes.

Methyl-β-cyclodextrin concurs with interleukin (IL)-4, IL-13 and IL-25 to induce alterations reminiscent of atopic dermatitis in reconstructed human epidermis

Methyl-β-cyclodextrin treatment combined to incubation with interleukin-4 reproduces major features of atopic dermatitis in a 3D-culture model.

Microscopy: access to the bigger picture in histology

Modeling dermatophytosis in reconstructed human epidermis: A new tool to study infection mechanisms and to test antifungal agents.

Modelling atopic dermatitis during the morphogenetic process involved in reconstruction of a human epidermis

Modelling the human epidermis in vitro: tools for basic and applied research

Non-senescent keratinocytes organize in plasma membrane submicrometric lipid domains enriched in sphingomyelin and involved in re-epithelialization

Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity.

Polysaccharide-coated PCL nanofibers for wound dressing applications.

Preparation and characterizations of EGDE crosslinked chitosan electrospun membranes.

Processing and characterization of the low density lipoprotein receptor in the human colonic carcinoma cell subclone HT29-18: a potential pathway for delivering therapeutic drugs and genes

Proteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factor

Reconstruction of normal and pathological human epidermis on polycarbonate filter

Responses of Reconstructed Human Epidermis to Trichophyton rubrum Infection and Impairment of Infection by the Inhibitor PD169316

Studies of cell signaling in a reconstructed human epidermis exposed to sensitizers: IL-8 synthesis and release depend on EGFR activation

Study of epidermal differentiation in human keratinocytes cultured in autocrine conditions.

TMEM45A Is Dispensable for Epidermal Morphogenesis, Keratinization and Barrier Formation

The CYP26 inhibitor R115866 potentiates the effects of all-trans retinoic acid on cultured human epidermal keratinocytes

The activation of cultured keratinocytes by cholesterol depletion during reconstruction of a human epidermis is reminiscent of monolayer cultures.

The dumb ErbB receptor helps healing

The inhibition of the expression of the small Rho GTPase Rac1 induces differentiation with no effect on cell proliferation in growing human adult keratinocytes

The small Rho GTPase Rac1 controls normal human dermal fibroblasts proliferation with phosphorylation of the oncoprotein c-myc

Transcriptional profiling after lipid raft disruption in keratinocytes identifies critical mediators of atopic dermatitis pathways.

Ultrastructural morphology of the male and female genital tracts of Psoroptes spp. (Acari: Astigmata: Psoroptidae).

Utilization of human cultured epidermal keratinocytes: irreversibility of the inhibition of proliferation induced in stored detached cultures

p38 MAPK-regulated EGFR internalization takes place in keratinocyte monolayer during stress conditions