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List of works by Jiekai Chen

A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

scientific article

BMI1 enables interspecies chimerism with human pluripotent stem cells

scientific article published in Nature Communications

BMP4 drives primed to naïve transition through PGC-like state

scientific article published on 19 May 2022

BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling

scientific article published on 11 May 2020

Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models

scientific article published on 01 December 2020

EMT and MET as paradigms for cell fate switching

scientific article published on 2 December 2011

Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity

scientific article published on 28 January 2014

Global Profiling of the Lysine Crotonylome in Different Pluripotent States

scientific article published on 01 February 2021

Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors

scientific article published on 15 November 2019

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs ⬇️

scientific article published on December 2, 2012

Host metabolism dysregulation and cell tropism identification in human airway and alveolar organoids upon SARS-CoV-2 infection

scientific article published on 12 December 2020

Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

scientific article published on 05 March 2021

JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency

scientific article published on 08 October 2020

Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells

scientific article

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs.

scientific article published on 22 September 2017

Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells

scientific article published on 18 September 2017

Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics

scientific article published on March 29, 2011

Reprogramming in suspension

scientific article published on 27 April 2012

Reprogramming of mouse and human somatic cells by high-performance engineered factors

scientific article published on 15 April 2011

Reprogramming of mouse and human somatic cells by high-performance engineered factors.

scientific article published on 11 March 2011

Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming

scientific article published on 26 May 2013

Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming

scientific article published on 13 February 2014

Towards an optimized culture medium for the generation of mouse induced pluripotent stem cells

scientific article

Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells

scientific article published in Nature Communications

Vitamin C modulates TET1 function during somatic cell reprogramming

scientific article published on 27 October 2013

scDIOR: single cell RNA-seq data IO software

scientific article published on 06 January 2022

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