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List of works by Leon Reubsaet

A pilot study showing differences in glycosylation patterns of IgG subclasses induced by pneumococcal, meningococcal, and two types of influenza vaccines.

scientific article

Absolute ProGRP quantification in a clinical relevant concentration range using LC-MS/MS and a comprehensive internal standard

scientific article published on 24 December 2008

Accelerated 18O-labeling in urinary proteomics

scientific article published on 03 November 2010

Acetylcholine in the corneal epithelium of diurnal and nocturnal mammals

scientific article

All-in-one paper-based sampling chip for targeted protein analysis

scientific article published on 20 August 2019

Analytical techniques used to study the degradation of proteins and peptides: chemical instability

scientific article published on 01 September 1998

Analytical techniques used to study the degradation of proteins and peptides: physical instability

scientific article published on 01 September 1998

Antibody-free biomarker determination: exploring molecularly imprinted polymers for pro-gastrin releasing peptide

scientific article published on 26 November 2014

Application of supplementary flow in comprehensive 2D liquid chromatography combining SEC and RPC.

scientific article published in March 2005

Atorvastatin does not affect the pharmacokinetics of cyclosporine in renal transplant recipients

scientific article published on 12 February 2005

Automated Protein Biomarker Analysis: on-line extraction of clinical samples by Molecularly Imprinted Polymers

scientific article published on 17 March 2017

Bradykinin analysis revived--a validated method for determination of its stable metabolite in whole blood by LC-MS/MS

scientific article published on 02 January 2014

Cinacalcet's effect on the pharmacokinetics of tacrolimus, cyclosporine and mycophenolate in renal transplant recipients

scientific article published on 23 October 2007

Comparison of newly developed immuno-MS method with existing DELFIA(®) immunoassay for human chorionic gonadotropin determination in doping analysis.

scientific article published in March 2013

Correction to: Exploring the peptide retention mechanism in molecularly imprinted polymers

scientific article published on 29 December 2017

Critical assessment of accelerating trypsination methods

scientific article published on 11 August 2011

Cyclic diguanylate regulation of Bacillus cereus group biofilm formation

scientific article published on 26 April 2016

Data-Independent Acquisition for the Orbitrap Q Exactive HF: A Tutorial

scientific article published on 17 January 2019

Declining intracellular T-lymphocyte concentration of cyclosporine a precedes acute rejection in kidney transplant recipients

scientific article published on 01 January 2008

Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LC-tandem MS.

scientific article published on 3 June 2005

Determination of ciclosporin A and its six main metabolites in isolated T-lymphocytes and whole blood using liquid chromatography-tandem mass spectrometry

scientific article published on 03 February 2007

Determination of ganciclovir in different matrices from solid organ transplanted patients treated with a wide range of concomitant drugs

scientific article published on 10 October 2006

Determining ProGRP and isoforms in lung and thyroid cancer patient samples: comparing an MS method with a routine clinical immunoassay

scientific article published on 12 February 2014

Digging deeper into the field of the small cell lung cancer tumor marker ProGRP: a method for differentiation of its isoforms

scientific article published on 12 December 2012

Dual-immuno-MS technique for improved differentiation power in heterodimeric protein biomarker analysis: determination and differentiation of human chorionic gonadotropin variants in serum

scientific article published on 2 August 2016

Elucidation of phosphatidylcholine composition in krill oil extracted from Euphausia superba

scientific article

Epitope analysis and detection of human chorionic gonadotropin (hCG) variants by monoclonal antibodies and mass spectrometry

scientific article

Evaluation of affinity-based serum clean-up in mass spectrometric analysis: Plastic vs monoclonal antibodies

scientific article published in October 2016

Evaluation of essential parameters in the chromatographic determination of cyclosporin A and metabolites using a D-optimal design

scientific article published in November 2002

Exploring the complementary selectivity of immunocapture and MS detection for the differentiation between hCG isoforms in clinically relevant samples

scientific article published in November 2009

Exploring the peptide retention mechanism in molecularly imprinted polymers.

scientific article published on 27 July 2017

Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane extraction.

scientific article published on 5 March 2011

Filter Plate-Based Screening of MIP SPE Materials for Capture of the Biomarker Pro-Gastrin-Releasing Peptide

scientific article published on 31 January 2017

Fundamental studies on the electrokinetic transfer of net cationic peptides across supported liquid membranes

scientific article published on 17 December 2010

High-performance liquid chromatography-mass spectrometry analysis of diltiazem and 11 of its phase I metabolites in human plasma

scientific article

Identification of a novel CYP2C19-mediated metabolic pathway of S-citalopram in vitro

scientific article published on 22 September 2009

Identification of unknown quaternary ammonium compounds in corneal epithelium and aqueous humor

scientific article

Immuno-MS based targeted proteomics: highly specific, sensitive, and reproducible human chorionic gonadotropin determination for clinical diagnostics and doping analysis

scientific article published on 30 August 2012

Immuno-capture as ultimate sample cleanup in LC-MS/MS determination of the early stage biomarker ProGRP

scientific article published on 01 September 2009

Immunocapture and LC-MS/MS for selective quantification and differentiation of the isozymes of the biomarker neuron-specific enolase in serum

scientific article published on 18 April 2013

Improving off-line accelerated tryptic digestion. Towards fast-lane proteolysis of complex biological samples

scientific article published on 13 May 2008

Instant on-paper protein digestion during blood spot sampling

scientific article published on 12 September 2017

Intake of grapefruit juice alters the metabolic pattern of cyclosporin A in renal transplant recipients.

scientific article published in October 2002

Integrated enzyme reactor and high resolving chromatography in "sub-chip" dimensions for sensitive protein mass spectrometry

scientific article

Ion-pair mediated transport of angiotensin, neurotensin, and their metabolites in liquid phase microextraction under acidic conditions

scientific article published in July 2005

Ion-pair mediated transport of small model peptides in liquid phase micro extraction under acidic conditions

scientific article

Isolation and mass spectrometry analysis of urinary extraexosomal proteins

scientific article published on 2 November 2016

Liquid chromatography mass spectrometry based characterization of epitope configurations

scientific article published on 03 November 2020

Liquid-phase microextraction based on carrier mediated transport combined with liquid chromatography-mass spectrometry. New concept for the determination of polar drugs in a single drop of human plasma

scientific article published in April 2005

Multiplexing determination of small cell lung cancer biomarkers and their isovariants in serum by immunocapture LC-MS/MS

scientific article published on 01 July 2014

Nano volume fractionation strategy for dilute-and-shoot injections in off-line loss-less proteomic workflows for extensive protein identifications of ultra-low sample amounts

scientific article published on 03 September 2019

On-Line multitasking analytical proteomics: how to separate, reduce, alkylate and digest whole proteins in an on-Line multidimensional chromatography system coupled to MS

scientific article published on 01 September 2008

One‐step functionalization of paper and simplified antibody immobilization for on‐the‐spot immunocapture from dried serum in liquid chromatography‐tandem mass spectrometry based targeted protein determination

scientific article published in 2024

Oxidation of recombinant methionyl human granulocyte colony stimulating factor

scientific article published in June 1998

Paper-based immunocapture for targeted protein analysis

scientific article published on 07 December 2018

Peptide imprinted receptors for the determination of the small cell lung cancer associated biomarker progastrin releasing peptide

scientific article

Pharmacokinetics of diltiazem and its metabolites in relation to CYP2D6 genotype

scientific article published in September 2002

Potential-driven peptide extractions across supported liquid membranes: investigation of principal operational parameters

scientific article published in June 2010

Precolumn fluorescence derivatization of the antagonist [Arg6,D-Trp7,9,MePhe8]-substance P[6-11] with benzoin in high-performance liquid chromatography and selective detection of arginine-containing fragments in its degradation products

scientific article published on 01 June 1996

Psychoactive drugs, alcohol, and severe hypoglycemia in insulin-treated diabetes: analysis of 141 cases

scientific article published in March 2005

Qualitative and quantitative aspects of the degradation of several tripeptides derived from the antitumour peptide antagonist [Arg(6), D-Trp(7,9), MePhe(8)] substance P[6-11]

scientific article published on 01 March 1999

Rapid isolation of angiotensin peptides from plasma by electromembrane extraction.

scientific article

Reduced elimination of cyclosporine A in elderly (>65 years) kidney transplant recipients

scientific article published in November 2008

Reduction of Cys36-Cys42 and Cys64-Cys74 disulfide bonds in recombinant human granulocyte colony stimulating factor

scientific article published in May 1999

Reversed-phase high-performance liquid chromatography and capillary electrophoresis in the stability study of the neuropeptide growth factor antagonist [Arg6,D-Trp7,9,MePhe8]-substance P (6-11): a comparative study

scientific article published on 01 July 1994

Sample preparation and determination of acetylcholine in corneal epithelium cells using liquid chromatography-tandem mass spectrometry

scientific article published in March 2003

Sample preparation and determination of gabapentin in venous and capillary blood using liquid chromatography-tandem mass spectrometry

scientific article published in February 2004

Screening for central nervous system-stimulating drugs in human plasma by liquid chromatography with mass spectrometric detection.

scientific article published on March 2004

Selective fishing of peptides with antibody-immobilized acrylate monoliths, coupled online with nanoLC-MS

scientific article published on 13 November 2018

Significantly altered systemic exposure to atorvastatin acid following gastric bypass surgery in morbidly obese patients.

scientific article published on 3 June 2009

Smart blood spots for whole blood protein analysis

scientific article published on 01 June 2018

Sports drug testing using immuno-MS: clinical study comprising administration of human chorionic gonadotropin to males

scientific article published on 01 December 2012

Structural identification of the degradation products of the antitumor peptide antagonist [Arg6,D-Trp7,9,MePhe8]substance P (6-11)

scientific article published on 01 December 1995

Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients

scientific article published in October 2004

Suction blister fluid as potential body fluid for biomarker proteins

scientific article published on 01 October 2007

Targeted determination of the early stage SCLC specific biomarker pro-gastrin-releasing peptide (ProGRP) at clinical concentration levels in human serum using LC-MS

scientific article published on 01 November 2007

The impact of high-dose acetylcholine on bovine corneal epithelium

scientific article published on 8 October 2015

The pros and cons of increased trypsin-to-protein ratio in targeted protein analysis

scientific article

The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis.

scientific article

Three-phase liquid-phase microextraction of weakly basic drugs from whole blood

scientific article published on 01 December 2003

To elute or not to elute in immunocapture bottom-up LC-MS.

scientific article published on 14 April 2017

Urinary proteomic shotgun approach for identification of potential acute rejection biomarkers in renal transplant recipients

scientific article published on 31 August 2012

Vaccination with outer membrane vesicles from Francisella noatunensis reduces development of francisellosis in a zebrafish model.

scientific article published on 27 October 2014

Why less is more when generating tryptic peptides in bottom-up proteomics.

scientific article published on 13 August 2014