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List of works by Maarten Altelaar

A CDK-mediated phosphorylation switch of disordered protein condensation

Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

scientific article published on 29 January 2020

Assessment of SRM, MRM(3) , and DIA for the targeted analysis of phosphorylation dynamics in non-small cell lung cancer.

scientific article

Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis

scientific article published on 15 December 2016

Automated High-Throughput Method for the Fast, Robust, and Reproducible Enrichment of Newly Synthesized Proteins

scientific article published on 03 December 2021

Automated, feature-based image alignment for high-resolution imaging mass spectrometry of large biological samples.

scientific article published on 18 March 2008

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts

scientific article published on 16 June 2016

Benchmarking multiple fragmentation methods on an orbitrap fusion for top-down phospho-proteoform characterization

scientific article published on 08 April 2015

Benchmarking stable isotope labeling based quantitative proteomics

scientific article published on 22 October 2012

CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC

scientific article published in 2024

Cellular imaging using matrix-enhanced and metal-assisted SIMS.

scientific article published on January 2010

Characterization of electron transfer dissociation in the Orbitrap Velos HCD cell

scientific article published on 20 April 2013

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux

scientific article published on 26 November 2019

Combined Quantitative (Phospho)proteomics and Mass Spectrometry Imaging Reveal Temporal and Spatial Protein Changes in Human Intestinal Ischemia-Reperfusion

scientific article published on 07 December 2021

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma

scientific article published on 17 June 2019

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

scientific article

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

scientific article published on 7 May 2015

Cultivation of Podospora anserina on soybean hulls results in an efficient enzyme cocktail for plant biomass hydrolysis

scientific article

Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis

scientific article published on 24 June 2021

Database independent proteomics analysis of the ostrich and human proteome.

scientific article published on 22 December 2011

Deep proteome profiling of Trichoplax adhaerens reveals remarkable features at the origin of metazoan multicellularity.

scientific article

Deletion of flbA results in increased secretome complexity and reduced secretion heterogeneity in colonies of Aspergillus niger

scientific article published on 22 March 2013

Determination of polycyclic aromatic hydrocarbons and polycylic aromatic sulfur heterocycles by high-performance liquid chromatography with fluorescence and atmospheric pressure chemical ionization mass spectrometry detection in seawater and [...]

scientific article

Diet-induced neuropeptide expression: feasibility of quantifying extended and highly charged endogenous peptide sequences by selected reaction monitoring

scientific article published on 16 September 2015

Differential proteomics reveals the hallmarks of seed development in common bean (Phaseolus vulgaris L.).

scientific article

Dimethyl isotope labeling assisted de novo peptide sequencing ⬇️

scientific article published on August 21, 2010

Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry.

scientific article

Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

scientific article (publication date: 6 December 2016)

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

scientific article

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

scientific article published in 2022

Elucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling

Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex

scientific article published in June 2017

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo

scientific article published on 20 August 2014

Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.

scientific article published on 5 November 2014

Gaining efficiency by parallel quantification and identification of iTRAQ-labeled peptides using HCD and decision tree guided CID/ETD on an LTQ Orbitrap.

scientific article

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.

scientific article published on 31 May 2017

Identification of a tumor-specific allo-HLA-restricted γδTCR

scientific article published on 01 October 2019

Identification of putative substrates for the periplasmic chaperone YfgM in Escherichia coli using quantitative proteomics

scientific article published on 17 November 2014

Imaging of peptides in the rat brain using MALDI-FTICR mass spectrometry.

scientific article

Improved identification of endogenous peptides from murine nervous tissue by multiplexed peptide extraction methods and multiplexed mass spectrometric analysis

scientific article published in February 2009

Improved peptide identification by targeted fragmentation using CID, HCD and ETD on an LTQ-Orbitrap Velos.

scientific article published on April 2011

Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra.

scientific article

In-depth profiling of post-translational modifications on the related transcription factor complexes TFIID and SAGA.

scientific article

Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell-Specific Proteases

scientific article published on 12 September 2016

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

scientific article published on 13 January 2017

Monitoring light/dark association dynamics of multi-protein complexes in cyanobacteria using size exclusion chromatography-based proteomics.

scientific article published on 29 April 2016

Multistep mechanism of G-quadruplex resolution during DNA replication

scientific article published on 24 September 2021

Myc coordinates transcription and translation to enhance transformation and suppress invasiveness

scientific article

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids ⬇️

scientific article published on 11 May 2015

Next-generation proteomics: towards an integrative view of proteome dynamics.

scientific article

Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)n and (X)nK/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics

scientific article published on 2 December 2016

PaDuA: A Python Library for High-Throughput (Phospho)proteomics Data Analysis

scientific article published on 21 December 2018

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

scientific article published on 28 August 2015

Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence

scientific article

Probing the Proteome Response to Toluene Exposure in the Solvent Tolerant Pseudomonas putida S12

article

Profiling of diet-induced neuropeptide changes in rat brain by quantitative mass spectrometry

scientific article published on 26 April 2013

Progressive methylation of ageing histones by Dot1 functions as a timer.

scientific article published on September 2011

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli

scientific article

Protein signatures associated with tumor cell dissemination in head and neck cancer

scientific article published on 22 January 2011

Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2)

scientific article

Proteomics and Phosphoproteomics Profiling of Drug-Addicted BRAFi-Resistant Melanoma Cells

scientific article published on 03 August 2021

Quantitative Map of Proteome Dynamics during Neuronal Differentiation.

scientific article published on February 2017

Quantitative Proteomics Illuminates a Functional Interaction between mDia2 and the Proteasome

scientific article published on 21 October 2016

Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway

scientific article published in April 2013

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

scientific article

Robust, Sensitive, and Automated Phosphopeptide Enrichment Optimized for Low Sample Amounts Applied to Primary Hippocampal Neurons.

scientific article published on 6 December 2016

Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence.

scientific article published on 2 June 2015

Similar is not the same: differences in the function of the (hemi-)cellulolytic regulator XlnR (Xlr1/Xyr1) in filamentous fungi.

scientific article

Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution.

scientific article published on 21 May 2014

Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage

scientific article published on 18 November 2021

Spatially Resolving the Secretome within the Mycelium of the Cell Factory Aspergillus niger

scientific article published on 09 April 2012

Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Display Altered Proteomes at Early Stages of Differentiation

scientific article published on 15 December 2021

Straightforward and de novo peptide sequencing by MALDI-MS/MS using a Lys-N metalloendopeptidase.

scientific article

Surface-enhanced resonance Raman spectroscopy as an identification tool in column liquid chromatography.

scientific article

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

scientific journal article

Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.

scientific article published on 13 July 2016

Temporal quantitative proteomics of mGluR-induced protein translation and phosphorylation in neurons

scientific article published on 10 September 2020

The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo

scientific article published on 18 February 2017

Tissue analysis with high-resolution imaging mass spectrometry.

scientific article

Tools and strategies for visualization of large image data sets in high-resolution imaging mass spectrometry.

scientific article

Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry.

scientific article published on 31 October 2012

Trends in ultrasensitive proteomics ⬇️

scientific article published on 07 January 2012

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities

scientific article published on 19 April 2020

Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD)

scientific article

Uncovering the abilities of Agaricus bisporus to degrade plant biomass throughout its life cycle.

scientific article published on 28 June 2015

Unravelling the Neospora caninum secretome through the secreted fraction (ESA) and quantification of the discharged tachyzoite using high-resolution mass spectrometry-based proteomics

scientific article

VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function

scientific article published on 23 August 2019

Vasohibins encode tubulin detyrosinating activity

scientific article

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