List of works - Asier Unciti-Broceta

A fluorescein-derived anthocyanidin-inspired pH sensor

A highly sensitive fluorescent viscosity sensor

scientific article published on 04 August 2012

A novel small molecule inhibitor of TRAF-dependent signalling inhibits breast cancer-induced osteoclastogenesis and prevents osteolysis

A yeast chemical genetic screen identifies inhibitors of human telomerase

scientific article

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective

scientific article

Advancing cancer drug discovery towards more agile development of targeted combination therapies

scientific article

Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity

scientific article published on 16 March 2015

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis

scientific article published on 01 July 2019

Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices

scientific article published on 08 November 2018

Bright insights into palladium-triggered local chemotherapy

scientific article published on 17 July 2018

Combining nebulization-mediated transfection and polymer microarrays for the rapid determination of optimal transfection substrates

scientific article

Conference Report: The 3rd International Symposium on Cellular Delivery of Therapeutic Macromolecules

scholarly article by Asier Unciti-Broceta published October 2010 in Therapeutic delivery

Deciphering cellular morphology and biocompatibility using polymer microarrays

scientific article

Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents

Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine

scientific article

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening

scientific article

Drug “Clicking” on Cell-Penetrating Fluorescent Nanoparticles for In Cellulo Chemical Proteomics

scientific article published on 04 September 2018

Efficient Palladium-Triggered Release of Vorinostat from a Bioorthogonal Precursor

scientific article published on 27 October 2016

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach.

scientific article

Far red and NIR dye-peptoid conjugates for efficient immune cell labelling and tracking in preclinical models

scholarly article by Kevin Dhaliwal et al published 2011 in MedChemComm

Flexible Fabrication of Microarrays of Microwells

Frontispiece: Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices

Gold-Triggered Uncaging Chemistry in Living Systems

Gold-Triggered Uncaging Chemistry in Living Systems.

scientific article

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

scientific article published on 10 January 2018

High-efficient transfection using cationic lipids with programmed biodegradability

scholarly article by Asier Unciti-Broceta et al published December 2010 in Drug Discovery Today

Innenrücktitelbild: Gold-Triggered Uncaging Chemistry in Living Systems (Angew. Chem. 41/2017)

Inside Back Cover: Gold-Triggered Uncaging Chemistry in Living Systems (Angew. Chem. Int. Ed. 41/2017)

Masking Strategies for the Bioorthogonal Release of Anticancer Glycosides

scholarly article published 21 November 2017

Metallofluorescent Nanoparticles for Multimodal Applications.

scientific article published on 5 January 2018

Multi-modal molecular imaging approaches to detect primary cells in preclinical models.

scientific article published on January 2011

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

scientific article published on 29 July 2014

Next-generation phenotypic screening

scientific article published on 30 June 2016

Non-toxic, highly efficient delivery of nucleic acids into challenging cells using safectin transfection reagent

article

Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis

scientific article published on 27 November 2020

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

scientific article published on 08 June 2021

Palladium-mediated dealkylation of N-propargyl-floxuridine as a bioorthogonal oxygen-independent prodrug strategy

scientific article

Palladium-mediated intracellular chemistry

scientific article published on 06 February 2011

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase

scientific article

Reduction of Different Electron-PoorN-Heteroarylhydrazines in Strong Basic Conditions

scientific article published on 01 January 2007

Regioselective one-pot synthesis of 9-alkyl-6-chloropyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazines. Reactivity of aliphatic and aromatic hydrazides

scientific article published in April 2005

Rise of the nanobots

Safe and efficient in vitro and in vivogene delivery: tripodal cationic lipids with programmed biodegradability

scholarly article by Asier Unciti-Broceta et al published 2011 in Journal of Materials Chemistry

Solid-phase synthesis of a lysine-capped bis-dendron with remarkable DNA delivery abilities

scientific article

Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: potent nucleic acid carriers.

scientific article

Strategies for the preparation of synthetic transfection vectors

scientific article published on January 2010

Synthesis of 6,8,9 poly-substituted purine analogue libraries as pro-apoptotic inducers of human leukemic lymphocytes and DAPK-1 inhibitors

scientific article published on May 2015

Synthesis of 9-alkyl-6-amino[1,2,4]triazolo[3,4-c]-5-azaquinoxalines. Mild and effective SNAr amination of highly electron-poor heterocycles

Synthesis of polystyrene microspheres and functionalization with Pd0 nanoparticles to perform bioorthogonal organometallic chemistry in living cells

scientific article published on 31 May 2012

Synthesis, penetrability and intracellular targeting of fluorescein-tagged peptoids and peptide-peptoid hybrids

scientific article

Targeted Molecular Construct for Bioorthogonal Theranostics of PD-L1-Expressing Cancer Cells

scientific article published in 2022

The use of solid supports to generate nucleic acid carriers.

scientific article

Tripod-like cationic lipids as novel gene carriers

scientific article

Very long-chain fatty tails for enhanced transfection

scientific article

List of works by Asier Unciti-Broceta

A fluorescein-derived anthocyanidin-inspired pH sensor

A highly sensitive fluorescent viscosity sensor

A novel small molecule inhibitor of TRAF-dependent signalling inhibits breast cancer-induced osteoclastogenesis and prevents osteolysis

A yeast chemical genetic screen identifies inhibitors of human telomerase

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective

Advancing cancer drug discovery towards more agile development of targeted combination therapies

Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity

An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis

Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices

Bright insights into palladium-triggered local chemotherapy

Combining nebulization-mediated transfection and polymer microarrays for the rapid determination of optimal transfection substrates

Conference Report: The 3rd International Symposium on Cellular Delivery of Therapeutic Macromolecules

Deciphering cellular morphology and biocompatibility using polymer microarrays

Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents

Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening

Drug “Clicking” on Cell-Penetrating Fluorescent Nanoparticles for In Cellulo Chemical Proteomics

Efficient Palladium-Triggered Release of Vorinostat from a Bioorthogonal Precursor

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach.

Far red and NIR dye-peptoid conjugates for efficient immune cell labelling and tracking in preclinical models

Flexible Fabrication of Microarrays of Microwells

Frontispiece: Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices

Gold-Triggered Uncaging Chemistry in Living Systems

Gold-Triggered Uncaging Chemistry in Living Systems.

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

High-efficient transfection using cationic lipids with programmed biodegradability

Innenrücktitelbild: Gold-Triggered Uncaging Chemistry in Living Systems (Angew. Chem. 41/2017)

Inside Back Cover: Gold-Triggered Uncaging Chemistry in Living Systems (Angew. Chem. Int. Ed. 41/2017)

Masking Strategies for the Bioorthogonal Release of Anticancer Glycosides

Metallofluorescent Nanoparticles for Multimodal Applications.

Multi-modal molecular imaging approaches to detect primary cells in preclinical models.

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

Next-generation phenotypic screening

Non-toxic, highly efficient delivery of nucleic acids into challenging cells using safectin transfection reagent

Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

Palladium-mediated dealkylation of N-propargyl-floxuridine as a bioorthogonal oxygen-independent prodrug strategy

Palladium-mediated intracellular chemistry

Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase

Reduction of Different Electron-PoorN-Heteroarylhydrazines in Strong Basic Conditions

Regioselective one-pot synthesis of 9-alkyl-6-chloropyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrazines. Reactivity of aliphatic and aromatic hydrazides

Rise of the nanobots

Safe and efficient in vitro and in vivogene delivery: tripodal cationic lipids with programmed biodegradability

Solid-phase synthesis of a lysine-capped bis-dendron with remarkable DNA delivery abilities

Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: potent nucleic acid carriers.

Strategies for the preparation of synthetic transfection vectors

Synthesis of 6,8,9 poly-substituted purine analogue libraries as pro-apoptotic inducers of human leukemic lymphocytes and DAPK-1 inhibitors

Synthesis of 9-alkyl-6-amino[1,2,4]triazolo[3,4-c]-5-azaquinoxalines. Mild and effective SNAr amination of highly electron-poor heterocycles

Synthesis of polystyrene microspheres and functionalization with Pd0 nanoparticles to perform bioorthogonal organometallic chemistry in living cells

Synthesis, penetrability and intracellular targeting of fluorescein-tagged peptoids and peptide-peptoid hybrids

Targeted Molecular Construct for Bioorthogonal Theranostics of PD-L1-Expressing Cancer Cells

The use of solid supports to generate nucleic acid carriers.

Tripod-like cationic lipids as novel gene carriers

Very long-chain fatty tails for enhanced transfection

eCF309: a potent, selective and cell-permeable mTOR inhibitor