List of works - Zachary J Reitman

2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations

scientific article

Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia.

scientific article

Detecting somatic mutations in genomic sequences by means of Kolmogorov-Arnold analysis

scientific article

Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.

scientific article published on 30 November 2012

Enzyme redesign guided by cancer-derived IDH1 mutations

scientific article (publication date: November 2012)

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

scientific article

Exomic sequencing of four rare central nervous system tumor types

scientific article published on April 2013

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

scientific article

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

scientific article

IDH1 and IDH2 hotspot mutations are not found in canine glioma.

scientific article published on July 2010

IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain

scientific article

Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

scientific article

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

scientific article

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

scientific article

Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors

scientific article

Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs.

scientific article

Relationship Between Time of First Publication and Subsequent Publication Success Among Non-PhD Physician-Scientists

scientific article

Releasing the block: setting differentiation free with mutant IDH inhibitors.

scientific article

Smaller protein, larger therapeutic potential: PPM1D as a new therapeutic target in brainstem glioma

scientific article published in September 2014

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL.

scientific article published in July 2014

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

scientific article published on 25 March 2013

The genetic landscape of anaplastic astrocytoma

scientific article

The genome-wide mutational landscape of pituitary adenomas.

scientific article published on 27 September 2016

List of works by Zachary J Reitman

2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations

Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia.

Detecting somatic mutations in genomic sequences by means of Kolmogorov-Arnold analysis

Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.

Enzyme redesign guided by cancer-derived IDH1 mutations

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

Exomic sequencing of four rare central nervous system tumor types

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

IDH1 and IDH2 hotspot mutations are not found in canine glioma.

IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain

Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors

Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs.

Relationship Between Time of First Publication and Subsequent Publication Success Among Non-PhD Physician-Scientists

Releasing the block: setting differentiation free with mutant IDH inhibitors.

Smaller protein, larger therapeutic potential: PPM1D as a new therapeutic target in brainstem glioma

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL.

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

The genetic landscape of anaplastic astrocytoma

The genome-wide mutational landscape of pituitary adenomas.