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List of works by Lieve Umans

A broken heart: a stretch too far: an overview of mouse models with mutations in stretch-sensor components

scientific article published on 20 August 2008

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion

scientific article published on September 2012

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells

scientific article

BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks

scientific article

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice

scientific article

Essential validation of gene trap mouse ES cell lines: a test case with the gene Ttrap

scientific article

FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate

scientific article published on 15 April 2009

Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo

scientific article published on October 2011

Functions of the type 1 BMP receptor Acvr1 (Alk2) in lens development: cell proliferation, terminal differentiation, and survival

scientific article published on 19 June 2008

Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis

scientific journal article

Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells

scientific journal article

Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.

scientific article published on May 2002

Robustness in angiogenesis: notch and BMP shaping waves

scientific article published on 30 December 2012

Smad1 and its target gene Wif1 coordinate BMP and Wnt signaling activities to regulate fetal lung development

scientific article published on 26 January 2011

Smad1/5 and Smad4 expression are important for osteoclast differentiation

scientific article published on July 2015

Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice

scientific article published on 24 April 2017

Smad1/5/8 are myogenic regulators of murine and human mesoangioblasts

scientific article

Smad5 is dispensable for adult murine hematopoiesis

scientific article published on 8 August 2006

Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades

scientific article published on 23 February 2012

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.

scientific article

TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo

scientific article

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

scientific article

The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation

scientific article published on 03 September 2009

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly

scientific article published on 11 April 2016

Transforming Growth Factor type beta and Smad family signaling in stem cell function

scientific article published on October 2009

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells

scientific article

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