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List of works by Susumu Itoh

A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver

scientific article published in December 1994

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

scientific article

Activities of drug-metabolizing enzymes in the liver of Suncus murinus: possible lack of N-acetyltransferase activity in liver cytosol

scientific article published on 01 March 1994

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

scientific article published on 4 August 2015

Assignment of the human interferon regulatory factor-1 (IRF1) gene to chromosome 5q23-q31

scientific article

Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice

scientific article published on 20 November 2007

Decrease in the content of cytochrome P450IIE by fasting in liver microsomes of house musk shrew (Suncus murinus).

scientific article published in May 1992

Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice.

scientific article published on 11 September 2012

Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene ⬇️

scientific article published on June 1, 1998

Dissociation of the AhR-ARNT complex by TGF-β-Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity

scientific article published on 14 May 2020

Effect of 26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3 on the expression of vitamin-D-responsive genes in vitamin-D-deficient mice

scientific article published on 01 December 1998

Establishment of immortal hepatocytes from a CYP3A7-transgenic/p53-knockout mouse

scientific article published in December 1995

Evidence for the lack of hepatic N-acetyltransferase in suncus (Suncus murinus)

scientific article published on 01 October 1995

Expression of CYP3A7, a human fetus-specific cytochrome P450, in cultured cells and in the hepatocytes of p53-knockout mice.

scientific article published on December 1995

Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development

scientific article published in January 2010

Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.

scientific article

Gene structure of mouse Cyp3a11: evidence for an enhancer element within its 5' flanking sequences.

scientific article published on February 1997

Genomic organization of human fetal specific P-450IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5' flanking region

scientific article

Human Ah receptor cDNA: analysis for highly conserved sequences.

scientific article published on July 1993

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

scientific article published in August 1998

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

scientific article

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

scientific article

Inhibition of the transcription of CYP1A1 gene by the upstream stimulatory factor 1 in rabbits. Competitive binding of USF1 with AhR.Arnt complex

scientific article published on 01 November 1997

Inhibitory effect of tuna peptide on endothelin production in cultured endothelial cells

scientific article published on 01 July 1994

Ligand-dependent selection of the receptor gene: segregation of IL-2 binding activity and anti-Tac reactivity by a single amino acid alteration in the Tac antigen (p55)

scientific article published on 01 January 1989

Methylation of Smad6 by protein arginine N-methyltransferase 1

scientific journal article

Molecular cloning and characterization of a novel putative STE20-like kinase in guinea pigs.

scientific article published on April 1997

Molecular cloning and functional expression of a mouse cytochrome P-450 (Cyp3a-13): examination of Cyp3a-13 enzyme to activate aflatoxin B1 (AFB1).

scientific article published on December 1994

Molecular cloning of 25-hydroxyvitamin D-3 24-hydroxylase (Cyp-24) from mouse kidney: its inducibility by vitamin D-3 ⬇️

scientific article published on October 17, 1995

Mouse cytochrome P450 (Cyp3a11): predominant expression in liver and capacity to activate aflatoxin B1.

scientific article published on April 1997

Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone

scientific article

Negative regulation of TGF-beta receptor/Smad signal transduction.

scientific article published on 20 February 2007

PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling

scientific article published on 04 February 2019

Pharmacological activity of chemically modified subfragment from human serum IgG. XIV. Inhibitory effect of carboxamide-methylated light chain (G1L) on tyrosine phosphorylation and tumor necrosis factor-alpha production from murine macrophages stimu

scientific article

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.

scientific article published on 27 April 2009

Promoter region of the human eosinophil cationic protein gene

scientific article published in January 1997

Regulation of CYP1A and CYP3A mRNAs by Ascorbic Acid in Guinea Pigs ⬇️

scientific article published on December 15, 1997

Regulation of the TMEPAI promoter by TCF7L2: the C-terminal tail of TCF7L2 is essential to activate the TMEPAI gene

scientific article published on 20 November 2015

Requirement of TCF7L2 for TGF-β-dependent Transcriptional Activation of the TMEPAI Gene ⬇️

scientific article published on September 30, 2010

SARA and Hgs attenuate susceptibility to TGF-beta1-mediated T cell suppression.

scientific article published on February 2003

Simultaneous expression of ferredoxin, ferredoxin reductase and P450 in COS7 cells

scientific article published on 01 January 1997

Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.

scientific article published on July 1995

Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes

scientific article published on 01 February 2000

Specific depletion of the B-cell population induced by aberrant expression of human interferon regulatory factor 1 gene in transgenic mice.

scientific article published on January 1991

Stable expression of cytochrome P450IIIA7 cDNA in human breast cancer cell line MCF-7 and its application to cytotoxicity testing.

scientific article published on January 1992

Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells

scientific article published in October 2002

Studies on pharmacological activation of human serum IgG by chemical modification and active subfragments. V. Mechanism of anti-inflammatory action of carboxamide-methylated L-chain (Fr. I-L) and H-chain (Fr. I-H) from human serum IgG

scientific article published on 01 October 1986

Studies on thermophile products. IX. Isofatty acid-containing phosphatidylglycerol that enhances the induction of concanavalin A-activated suppressor T cells

scientific article published on 01 September 1994

Studies on thermophile products. VII. Effect of 1,3-di-14-methylpentadecanoyl glycerol and its related isofatty acids on T cell proliferation in vitro

scientific article published on 01 June 1994

Studies on thermophile products. X. Further biological properties of isofatty acid-containing phosphatidylglycerol that enhances the induction of suppressor T cells

scientific article published on 01 November 1994

TGF- β Signaling Cooperates with AT Motif-Binding Factor-1 for Repression of the α -Fetoprotein Promoter

scientific article published on 3 July 2014

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α.

scientific article

TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling

scientific article

TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells

scientific article

The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

scientific article published on 01 August 1998

Upstream stimulatory factor 1 (USF1) suppresses induction of CYP1A1 mRNA by 3-methylcholanthrene (MC) in HepG2 cells

scientific article published on 01 November 1997

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