Search filters

List of works by Umberto Piarulli

2-(2-Hydroxyaryl)cinnamic amides: a new class of axially chiral molecules

A Catalytic and Enantioselective Desymmetrization of meso Cyclic Allylic Bisdiethylphosphates with Organozinc Reagents

A Catalytic and Enantioselective Desymmetrization of meso Cyclic Allylic Bisdiethylphosphates with Organozinc Reagents

scholarly article by Umberto Piarulli et al published 13 January 2003 in Angewandte Chemie International Edition

A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday

scientific article published in 2022

A Mixed Ligand Approach for the Asymmetric Hydrogenation of 2-Substituted Pyridinium Salts

scholarly article by Marc Renom-Carrasco et al published 12 July 2016 in Advanced Synthesis & Catalysis

A Modular Approach to a New Class of Monodentate Chiral Phosphorus Ligands and Their Application in Enantioselective Copper-Catalysed Conjugate Additions of Diethylzinc to Cyclohexenone

article

A carbonylative cross-coupling strategy to the total synthesis of the sarcodictyins: preliminary studies and synthesis of a cyclization precursor

A library approach to the development of BenzaPhos: highly efficient chiral supramolecular ligands for asymmetric hydrogenation

scientific article

A new method for the solution and solid phase synthesis of chiral β-sulfonopeptides under mild conditions

article

A practical approach to the resolution of racemic N-benzyl alpha-amino acids by liquid-liquid extraction with a lipophilic chiral salen-cobalt(III) complex

scientific article published in April 2006

A trifunctional steroid-based scaffold for combinatorial chemistry

article

Acceleration of hemiacetal cleavage through hydrogen bonding: a new synthetic catalyst with balanced conformational flexibility and preorganization

Assisted Tandem Catalysis: Metathesis Followed by Asymmetric Hydrogenation from a Single Ruthenium Source

scholarly article by Marc Renom-Carrasco et al published 6 July 2015 in Advanced Synthesis & Catalysis

Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts

scientific article published on 03 June 2016

Asymmetric Transfer Hydrogenation of Ketones with Modified Grubbs Metathesis Catalysts: On the Way to a Tandem Process

Bifunctional 2,5-Diketopiperazines as Efficient Organocatalysts for the Enantioselective Conjugate Addition of Aldehydes to Nitroolefins

article

Bifunctional 2,5-Diketopiperazines as Rigid Three-Dimensional Scaffolds in Receptors and Peptidomimetics

article

Cell-penetrating peptides containing 2,5-diketopiperazine (DKP) scaffolds as shuttles for anti-cancer drugs: conformational studies and biological activity

scientific article published on 22 April 2020

ChemInform Abstract: A Carbonylative Cross-Coupling Strategy to the Total Synthesis of the Sarcodictyins: Preliminary Studies and Synthesis of a Cyclization Precursor

ChemInform Abstract: Assisted Tandem Catalysis: Metathesis Followed by Asymmetric Hydrogenation from a Single Ruthenium Source

ChemInform Abstract: Asymmetric Transfer Hydrogenation of Ketones with Modified Grubbs′ Metathesis Catalysts: On the Way to a Tandem Process

ChemInform Abstract: Bifunctional 2,5-Diketopiperazines as Efficient Organocatalysts for the Enantioselective Conjugate Addition of Aldehydes to Nitroolefins

article

ChemInform Abstract: Bifunctional 2,5-Diketopiperazines as Rigid Three-Dimensional Scaffolds in Receptors and Peptidomimetics

ChemInform Abstract: Chiral (Cyclopentadienone)iron Complexes for the Catalytic Asymmetric Hydrogenation of Ketones

ChemInform Abstract: Combination of a Binaphthol-Derived Phosphite and a C1-Symmetric Phosphinamine Generates Heteroleptic Catalysts in Rh- and Pd-Mediated Reactions

ChemInform Abstract: Computer-Assisted Design and Synthetic Applications of Chiral Enol Borinates: Novel, Highly Enantioselective Aldol Reagents

ChemInform Abstract: Discovery of a New Efficient Chiral Ligand for Copper-Catalyzed Enantioselective Michael Additions by High-Throughput Screening of a Parallel Library

ChemInform Abstract: Discovery of a New Efficient Chiral Ligand for Copper-Catalyzed Enantioselective Michael Additions by High-Throughput Screening of a Parallel Library

ChemInform Abstract: Effect of Ligands and Additives on the Palladium-Promoted Carbonylative Coupling of Vinyl Stannanes and Electron-Poor Enol Triflates

ChemInform Abstract: Enantioselective Rh-Catalyzed Addition of Arylboronic Acids to N-Tosylarylimines

article

ChemInform Abstract: Optimization of New Chiral Ligands for the Copper-Catalyzed Enantioselective Conjugate Addition of Et2Zn to Nitroolefins by High-Throughput Screening of a Parallel Library

article

ChemInform Abstract: Synthesis of (R)-BINOL-Derived (Cyclopentadienone)Iron Complexes and Their Application in the Catalytic Asymmetric Hydrogenation of Ketones

ChemInform Abstract: Synthetic Studies on Sarcodictyins and Eleutherobin: Synthesis of Fully Functionalized Cyclization Precursors

ChemInform Abstract: Ureas: New Efficient Lewis Base Catalysts for the Allylation of Aldehydes

Chiral (Cyclopentadienone)iron Complexes for the Catalytic Asymmetric Hydrogenation of Ketones

article published in 2015

Chiral (salen)Co(III)(N-benzyl-l-serine)-derived phosphites: monodentate P-ligands for enantioselective catalytic applications

Combination of a binaphthol-derived phosphite and a C1-symmetric phosphinamine generates heteroleptic catalysts in Rh- and Pd-mediated reactions

scientific article published on 21 May 2009

Combinations of Acidic and Basic Monodentate Binaphtholic Phosphites as Supramolecular Bidentate Ligands for Enantioselective Rh-Catalyzed Hydrogenations

Combinatorial Libraries of Chiral Ligands for Enantioselective Catalysis

Combinatorial Libraries of Chiral Ligands for Enantioselective Catalysis

scientific article published on 01 August 2003

Combinatorial Libraries: Studies in Molecular Recognition and the Quest for New Catalysts

article published in 1997

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

scientific article published on March 2015

Computer-Assisted Design and Synthetic Applications of Chiral Enol Borinates: Novel, Highly Enantioselective Aldol Reagents

article published in 1998

Conjugates of Cryptophycin and RGD or isoDGR Peptidomimetics for Targeted Drug Delivery

scientific article published on 07 June 2019

Copper Phosphoramidite-Catalyzed Enantioselective Desymmetrization of meso-Cyclic Allylic Bisdiethyl Phosphates

Copper Phosphoramidite-Catalyzed Enantioselective Desymmetrization ofmeso-Cyclic Allylic Bisdiethyl Phosphates

scientific article published in 2003

Copper catalysed 1,4-addition of organozinc reagents to α,β-unsaturated carbonyl compounds: a mechanistic investigation

article

Copper-Catalysed, Enantioselective Desymmetrisation ofmeso Cyclic Allylic Bis(diethyl phosphates) with Organozinc Reagents

Copper-Catalyzed, Enantioselective Desymmetrization of meso Cyclic Allylic Bis(diethyl phosphates) with Organozinc Reagents

Cyclative cleavage via solid-phase supported stabilized sulfur ylides: synthesis of macrocyclic lactones

Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands

Cyclic RGD and <i>iso</i>DGR Integrin Ligands Containing <i>cis</i>-2-amino-1-cyclopentanecarboxylic (<i>cis</i>-β-ACPC) Scaffolds

scientific article published on 16 December 2020

Cyclic RGD-peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.

scientific article published in November 2009

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

scientific article

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

scientific article published on 19 February 2013

Determination of the binding epitope of RGD-peptidomimetics to αvβ3 and α(IIb)β3 integrin-rich intact cells by NMR and computational studies.

scientific article published on June 2013

Discovery of a New Efficient Chiral Ligand for Copper-Catalyzed Enantioselective Michael Additions by High-Throughput Screening of a Parallel Library

article

Discovery of a new efficient chiral ligand for copper-catalyzed enantioselective Michael additions by high-throughput screening of a parallel library.

scientific article

Effect of Ligands and Additives on the Palladium-Promoted Carbonylative Coupling of Vinyl Stannanes and Electron-Poor Enol Triflates

article

Effects of a novel cyclic RGD peptidomimetic on cell proliferation, migration and angiogenic activity in human endothelial cells

scientific article published on 21 May 2014

Efficient resolution of racemic N-benzyl beta3-amino acids by iterative liquid-liquid extraction with a chiral (salen)cobalt(III) complex as enantioselective selector

scientific article

Enantioselective Conjugate Addition of Phenylboronic Acid to Enones Catalyzed by a Chiral Tropos/Atropos Rhodium Complex at the Coalescence Temperature

article

Enantioselective Cyanosilylation of Aldehydes Catalyzed by a Diastereomeric Mixture of Atropisomeric Thioureas

Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes

scientific article published on 01 September 2017

Enantioselective Rh-Catalyzed Addition of Arylboronic Acids to N-Tosylarylimines

article

Enantioselective binding of dipeptides using acyclic receptors

article published in 2001

Enantioselective conjugate addition of phenylboronic acid to enones catalysed by a chiral tropos/atropos rhodium complex at the coalescence temperature

scientific article published on 21 September 2005

Enantioselective cyanosilylation of aldehydes catalysed by a diastereomeric mixture of atropisomeric thioureas

Entdeckung eines effizienten chiralen Liganden für die Cu-katalysierte enantioselektive Michael-Addition durch High-Throughput-Screening einer Parallelbibliothek

article

Expanding the Catalytic Scope of (Cyclopentadienone)iron Complexes to the Hydrogenation of Activated Esters to Alcohols

article

Foldamers of bifunctional diketopiperazines displaying a β-bend ribbon structure

article published in 2010

Highly enantioselective Rh-catalyzed hydrogenations with heterocombinations of pentafluorobenzyl- and methoxybenzyl-derived binaphthyl phosphites

Hydrogen-Bonding Donor/Acceptor Scales inβ-Sulfonamidopeptides

Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations

Inside Cover: Cyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin Ligands (Chem. Eur. J. 20/2012)

Inside Cover: Expanding the Catalytic Scope of (Cyclopentadienone)iron Complexes to the Hydrogenation of Activated Esters to Alcohols (ChemCatChem 22/2016)

scholarly article by Piotr Gajewski et al published 22 November 2016 in ChemCatChem

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

scientific article

Intramolecular Palladium-Catalyzed Aminocarboxylation of Olefins as a Direct Route to Bicyclic Oxazolidinones

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

scientific article published on 21 September 2017

Investigation of a New Family of Chiral Ligands for Enantioselective Catalysis via Parallel Synthesis and High-Throughput Screening

Kiss and Run: Promoting Effective and Targeted Cellular Uptake of a Drug Delivery Vehicle Composed of an Integrin-Targeting Diketopiperazine Peptidomimetic and a Cell-Penetrating Peptide

scientific article published on 19 June 2019

Metallohosts Derived from the Assembly of Sugars around Transition Metals: The Complexation of Alkali Metal Cations ⬇️

scientific article published on December 17, 1997

Optimization of New Chiral Ligands for the Copper-Catalysed Enantioselective Conjugate Addition of Et2Zn to Nitroolefins by High-Throughput Screening of a Parallel Library

article

Peptide bond formation using an enzyme mimicking approach

Peptide bond formation using an enzyme mimicking approach

PhthalaPhos: Chiral Supramolecular Ligands for Enantioselective Rhodium-Catalyzed Hydrogenation Reactions

scientific article published on 01 September 2010

Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors

scientific article published on 29 March 2019

Resolution of RacemicN-Benzyl α-Amino Acids by Liquid-Liquid Extraction: A Practical Method Using a Lipophilic Chiral Cobalt(III) Salen Complex and Mechanistic Studies

scholarly article by Pawel Dzygiel et al published March 2008 in European Journal of Organic Chemistry

Rh-Catalyzed Asymmetric Hydrogenation of Prochiral Olefins with a Dynamic Library of Chiral TROPOS Phosphorus Ligands

Rh-catalysed asymmetric hydrogenations with a dynamic library of chiral tropos phosphorus-ligands

Rh-catalyzed asymmetric hydrogenation of prochiral olefins with a dynamic library of chiral TROPOS phosphorus ligands

scientific article published in November 2005

Rh-catalyzed enantioselective conjugate addition of arylboronic acids with a dynamic library of chiral tropos phosphorus ligands

scientific article published in January 2007

Rhodium-Catalyzed Asymmetric Reactions with a Dynamic Library of Chiral Tropos Phosphorus Ligands

scholarly article by Cesare Gennari et al published 25 July 2006 in ChemInform

Rhodium-catalyzed asymmetric hydrogenation of olefins with PhthalaPhos, a new class of chiral supramolecular ligands

scientific article

Rhodium-catalyzed asymmetric reactions with a dynamic library of chiral tropos phosphorus ligands

scholarly article by Cesare Gennari et al published 1 January 2006 in Pure and Applied Chemistry

Selective O-acylation of unprotected N-benzylserine methyl ester and O,N-acyl transfer in the formation of cyclo[Asp-Ser] diketopiperazines

article

Solid-Phase Synthesis of Peptides Containing Reverse-Turn Mimetic Bicyclic Lactams

Stereocontrolled synthesis of polyketide libraries: Boron-mediated aldol reactions with aldehydes on solid support

article

Stereoselective aldol reactions of γ-thiobutyrolactone: The benzaldehyde anomaly

SupraBox: Chiral Supramolecular Oxazoline Ligands

Supramolecular ligand-ligand and ligand-substrate interactions for highly selective transition metal catalysis.

scientific article

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

scientific article published on 22 March 2019

Synthesis and Screening of New Chiral Ligands for the Copper-Catalysed Enantioselective Allylic Substitution

scholarly article by Sandrine Ongeri et al published October 2002 in Helvetica Chimica Acta

Synthesis and Screening of New Chiral Ligands for the Copper-Catalyzed Enantioselective Allylic Substitution

Synthesis and biological evaluation (in vitro and in vivo) of cyclic arginine-glycine-aspartate (RGD) peptidomimetic-paclitaxel conjugates targeting integrin αVβ3.

scientific article

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

scientific article

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

scientific article

Synthesis and conformational studies of a stable peptidomimetic β-hairpin based on a bifunctional diketopiperazine turn inducer

Synthesis and conformational studies of peptidomimetics containing a new bifunctional diketopiperazine scaffold acting as a beta-hairpin inducer.

scientific article published on 13 December 2007

Synthesis of (R)-BINOL-Derived (Cyclopentadienone)iron Complexes and Their Application in the Catalytic Asymmetric Hydrogenation of Ketones

Synthesis of (S)- and (R)-5-oxo-piperazine-2-carboxylic acid and its application to peptidomimetics

scientific article published in November 2009

Synthesis of Combinatorial Libraries of Vinylogous Sulfonamidopeptides (vs-Peptides)

Synthesis of [Bis(hexamethylene)cyclopentadienone]iron Tricarbonyl and its Application to the Catalytic Reduction of C=O Bonds

scholarly article by Sofia Vailati Facchini et al published 28 March 2017 in ChemCatChem

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

scientific article

Synthesis, Conformational Studies and Binding Properties of Acyclic Receptors for N-Protected Amino Acids and Dipeptides

article

Synthetic studies on sarcodictyins and eleutherobin: Synthesis of fully functionalized cyclization precursors

Synthetic studies on the sarcodictyins: synthesis of fully functionalized cyclization precursors

The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin α v β 3

article

Toward the first nonpeptidic molecular tong inhibitor of wild-type and mutated HIV-1 protease dimerization

scientific article published on November 2010

Tumor Targeting with an isoDGR-Drug Conjugate

scientific article published on 27 April 2017

Ureas: New efficient Lewis base catalysts for the allylation of aldehydes

Paulina is supported by:

About Paulina

Help