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List of works by Ákos Nyerges

A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species

scientific article published on 16 February 2016

A standardized workflow for surveying recombinases expands bacterial genome-editing capabilities.

scientific article

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

scientific article published on 10 February 2019

Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides

scientific article published on 24 May 2018

CRISPR-interference based modulation of mobile genetic elements in bacteria

CRISPR-interference-based modulation of mobile genetic elements in bacteria

scientific article published on 15 March 2019

Conditional DNA repair mutants enable highly precise genome engineering

scientific article published on 05 February 2014

Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.

scientific article published on 5 June 2018

Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity

scientific article published on 10 December 2019

Enzyme promiscuity shapes adaptation to novel growth substrates

scientific article published on 08 April 2019

Enzyme promiscuity shapes evolutionary innovation and optimization

article

Genome-Wide Abolishment of Mobile Genetic Elements Using Genome Shuffling and CRISPR/Cas-Assisted MAGE Allows the Efficient Stabilization of a Bacterial Chassis

scientific article published on 20 April 2017

Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network.

scientific article published on 8 July 2014

High-Efficiency Multi-site Genomic Editing of Pseudomonas putida through Thermoinducible ssDNA Recombineering

scientific article published on 26 February 2020

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

scientific article published on 22 December 2020

Improved bacterial recombineering by parallelized protein discovery

scientific article published on 28 May 2020

Improved bacterial recombineering by parallelized protein discovery

scientific article published on 16 January 2020

Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

scientific article published on 01 August 2019

Mismatch repair hierarchy of Pseudomonas putida revealed by mutagenic ssDNA recombineering of the pyrF gene

scientific article published on 07 November 2019

Multiple-Site Diversification of Regulatory Sequences Enables Interspecies Operability of Genetic Devices

scientific article published on 18 December 2019

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity

scientific article published on 10 May 2018

Perturbation of iron homeostasis promotes the evolution of antibiotic resistance.

scientific article published on 24 July 2014

Phenotypic heterogeneity promotes adaptive evolution.

scientific article

Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota

scientific article published on 17 December 2018

Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations

scientific article published on 23 August 2019

Rational design of balanced dual-targeting antibiotics with limited resistance

scientific article published on 05 October 2020

Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors

scientific article published on 11 February 2020

System-level genome editing in microbes

scientific article

Towards next-generation cell factories by rational genome-scale engineering

ssDNA recombineering boosts in vivo evolution of nanobodies displayed on bacterial surfaces

scientific article published on 07 October 2021