List of works - Sylvia Fitting

Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain

scientific article

Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices.

scientific article published on 18 March 2016

Cue effects on memory for location when navigating spatial displays

scientific article published on 28 July 2009

Cue usage in memory for location when orientation is fixed.

scientific article published in September 2008

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

scientific article published on 20 April 2012

Differential long-term neurotoxicity of HIV-1 proteins in the rat hippocampal formation: a design-based stereological study

scientific article published on January 2008

Dose-dependent long-term effects of Tat in the rat hippocampal formation: a design-based stereological study.

scientific article published on April 2010

Dose-dependent neurocognitive deficits following postnatal day 10 HIV-1 viral protein exposure: Relationship to hippocampal anatomy parameters.

scientific article published on 27 October 2017

Effects of HIV-1 Tat on enteric neuropathogenesis.

scientific article

Effects of chronic adult dietary restriction on spatial learning in the aged F344 x BN hybrid F1 rat

scientific article

Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein

scientific article

Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids

scientific article published on 18 November 2020

Exercise in Adulthood after Irradiation of the Juvenile Brain Ameliorates Long-Term Depletion of Oligodendroglial Cells

scientific article

External Cue Effects on Memory for Spatial Location within a Rotated Task Field

GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration

scientific article published on 15 March 2021

HIV-1 Tat causes cognitive deficits and selective loss of parvalbumin, somatostatin, and neuronal nitric oxide synthase expressing hippocampal CA1 interneuron subpopulations.

scientific article

HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system.

scientific article

HIV-1 coinfection and morphine coexposure severely dysregulate hepatitis C virus-induced hepatic proinflammatory cytokine release and free radical production: increased pathogenesis coincides with uncoordinated host defenses

scientific article published on 7 September 2011

HIV-1 proteins, Tat and gp120, target the developing dopamine system

scientific article published on January 2015

Inhibition of GABAergic Neurotransmission by HIV-1 Tat and Opioid Treatment in the Striatum Involves μ-Opioid Receptors.

scientific article

Inhibitory Control Deficits Associated with Upregulation of CB1R in the HIV-1 Tat Transgenic Mouse Model of Hand

scientific article published on 01 August 2019

Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.

scientific article

Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons

scientific article

Intra-accumbal Tat1-72 alters acute and sensitized responses to cocaine

scientific article published on October 2008

Intrahippocampal injections of Tat: effects on prepulse inhibition of the auditory startle response in adult male rats.

scientific article published on 21 June 2006

Lateralized response of dynorphin a peptide levels after traumatic brain injury

scientific article

Memory for spatial location: cue effects as a function of field rotation

scientific article published in October 2007

Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat

scientific article published on 16 August 2021

Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.

scientific article

Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain

scientific article published on 19 November 2011

Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice.

scientific article

Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at μ-opioid receptor-expressing glia

scientific article published on 18 November 2011

Neonatal hippocampal Tat injections: developmental effects on prepulse inhibition (PPI) of the auditory startle response.

scientific article

Neonatal intrahippocampal HIV-1 protein Tat(1-86) injection: neurobehavioral alterations in the absence of increased inflammatory cytokine activation

scientific article

Neonatal intrahippocampal glycoprotein 120 injection: the role of dopaminergic alterations in prepulse inhibition in adult rats

scientific article published on 19 June 2006

Neonatal intrahippocampal gp120 injection: an examination early in development

scientific article

Neonatal intrahippocampal injection of the HIV-1 proteins gp120 and Tat: differential effects on behavior and the relationship to stereological hippocampal measures

scientific article

Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS

scientific article published on 13 August 2018

Oligodendrocytes Are Targets of HIV-1 Tat: NMDA and AMPA Receptor-Mediated Effects on Survival and Development.

scientific article

Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity.

scientific article published on January 2014

Opiate drug use and the pathophysiology of neuroAIDS.

scientific article

Opioid and neuroHIV Comorbidity - Current and Future Perspectives

scientific article published on 02 September 2020

Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells

scientific article published on 10 June 2019

Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis

scientific article

Role of adrenal glucocorticoid signaling in prefrontal cortex gene expression and acute behavioral responses to ethanol

scientific article

Sensitization of enteric neurons to morphine by HIV-1 Tat protein.

scientific article

Shape effects on memory for location

scientific article published in August 2007

Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice.

scientific article published on 4 December 2012

The effects of human immunodeficiency virus infection on the expression of the drug efflux proteins P-glycoprotein and breast cancer resistance protein in a human intestine model

scientific article

beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.

scientific article

List of works by Sylvia Fitting

Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain

Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices.

Cue effects on memory for location when navigating spatial displays

Cue usage in memory for location when orientation is fixed.

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

Differential long-term neurotoxicity of HIV-1 proteins in the rat hippocampal formation: a design-based stereological study

Dose-dependent long-term effects of Tat in the rat hippocampal formation: a design-based stereological study.

Dose-dependent neurocognitive deficits following postnatal day 10 HIV-1 viral protein exposure: Relationship to hippocampal anatomy parameters.

Effects of HIV-1 Tat on enteric neuropathogenesis.

Effects of chronic adult dietary restriction on spatial learning in the aged F344 x BN hybrid F1 rat

Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein

Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids

Exercise in Adulthood after Irradiation of the Juvenile Brain Ameliorates Long-Term Depletion of Oligodendroglial Cells

External Cue Effects on Memory for Spatial Location within a Rotated Task Field

GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration

HIV-1 Tat causes cognitive deficits and selective loss of parvalbumin, somatostatin, and neuronal nitric oxide synthase expressing hippocampal CA1 interneuron subpopulations.

HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system.

HIV-1 coinfection and morphine coexposure severely dysregulate hepatitis C virus-induced hepatic proinflammatory cytokine release and free radical production: increased pathogenesis coincides with uncoordinated host defenses

HIV-1 proteins, Tat and gp120, target the developing dopamine system

Inhibition of GABAergic Neurotransmission by HIV-1 Tat and Opioid Treatment in the Striatum Involves μ-Opioid Receptors.

Inhibitory Control Deficits Associated with Upregulation of CB1R in the HIV-1 Tat Transgenic Mouse Model of Hand

Interactive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.

Interactive comorbidity between opioid drug abuse and HIV-1 Tat: chronic exposure augments spine loss and sublethal dendritic pathology in striatal neurons

Intra-accumbal Tat1-72 alters acute and sensitized responses to cocaine

Intrahippocampal injections of Tat: effects on prepulse inhibition of the auditory startle response in adult male rats.

Lateralized response of dynorphin a peptide levels after traumatic brain injury

Memory for spatial location: cue effects as a function of field rotation

Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat

Morphine Tolerance and Physical Dependence Are Altered in Conditional HIV-1 Tat Transgenic Mice.

Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain

Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice.

Morphine potentiates neurodegenerative effects of HIV-1 Tat through actions at μ-opioid receptor-expressing glia

Neonatal hippocampal Tat injections: developmental effects on prepulse inhibition (PPI) of the auditory startle response.

Neonatal intrahippocampal HIV-1 protein Tat(1-86) injection: neurobehavioral alterations in the absence of increased inflammatory cytokine activation

Neonatal intrahippocampal glycoprotein 120 injection: the role of dopaminergic alterations in prepulse inhibition in adult rats

Neonatal intrahippocampal gp120 injection: an examination early in development

Neonatal intrahippocampal injection of the HIV-1 proteins gp120 and Tat: differential effects on behavior and the relationship to stereological hippocampal measures

Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS

Oligodendrocytes Are Targets of HIV-1 Tat: NMDA and AMPA Receptor-Mediated Effects on Survival and Development.

Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity.

Opiate drug use and the pathophysiology of neuroAIDS.

Opioid and neuroHIV Comorbidity - Current and Future Perspectives

Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells

Regional heterogeneity and diversity in cytokine and chemokine production by astroglia: differential responses to HIV-1 Tat, gp120, and morphine revealed by multiplex analysis

Role of adrenal glucocorticoid signaling in prefrontal cortex gene expression and acute behavioral responses to ethanol

Sensitization of enteric neurons to morphine by HIV-1 Tat protein.

Shape effects on memory for location

Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice.

The effects of human immunodeficiency virus infection on the expression of the drug efflux proteins P-glycoprotein and breast cancer resistance protein in a human intestine model

beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.