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List of works by Katalin Susztak

'Back and forth' from models to patients to understand kidney disease: an interview with Katalin Susztak

scientific article published in December 2014

A High Fat Diet During Pregnancy and Lactation Induces Cardiac and Renal Abnormalities in GLUT4 +/- Male Mice

scientific article

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury

scientific article published on 21 April 2020

A multicolor podocyte reporter highlights heterogeneous podocyte changes in focal segmental glomerulosclerosis

scientific article

A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes

scientific article published on 22 April 2019

A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8.

scientific article published on 2 June 2010

ADCK4 "reenergizes" nephrotic syndrome

scientific article published on 25 November 2013

APOL1 Variants: From Parasites to Kidney Function to Cardiovascular Disease

scientific article published on February 2016

ASEP: Gene-based detection of allele-specific expression cross individuals in a population by RNA sequencing

scientific article published on 11 May 2020

Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.

scientific article

Adiponectin promotes functional recovery after podocyte ablation

scientific article published on 18 January 2013

Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting

scientific article published on 09 January 2019

Animal models of renal disease

scientific article published on 01 March 2008

Author Correction: FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy

scientific article published on 24 October 2019

Benign and tumor parenchyma metabolomic profiles affect compensatory renal growth in renal cell carcinoma surgical patients.

scientific article published on 20 July 2017

Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations

scientific article

Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

scientific article

DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC study

scientific article published on 09 February 2014

DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development

scientific article published on 08 March 2019

DNMT1 in Six2 progenitor cells is essential for transposable element silencing and kidney development

article

Deep learning enables accurate clustering with batch effect removal in single-cell RNA-seq analysis

scientific article published on 11 May 2020

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

scientific article published on December 2014

Defining the lineage of thermogenic perivascular adipose tissue

scientific article published on 12 April 2021

Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism

scientific article published on 8 June 2015

Developing Treatments for Chronic Kidney Disease in the 21st Century

scientific article published on November 2016

Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog

scientific article published on 3 May 2016

Diabetic kidney disease.

scientific article published on 30 July 2015

Diabetic nephropathy: a frontier for personalized medicine

scientific article

Diabetic nephropathy: a national dialogue

scientific article published on 20 June 2013

Diet-Induced Podocyte Dysfunction in Drosophila and Mammals

scientific article

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

scientific article published on 15 June 2020

Dnmt3a and Dnmt3b-Decommissioned Fetal Enhancers are Linked to Kidney Disease

scientific article published on 03 March 2020

Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies

scientific article published on 26 November 2019

Emerging role of autophagy in kidney function, diseases and aging

scientific article

Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development

scientific article

Epigenetics: a new way to look at kidney diseases

scientific article

Epigenomics: the science of no-longer-junk DNA. Why study it in chronic kidney disease?

scientific article

Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans

scientific article

Epithelial Plasticity versus EMT in Kidney Fibrosis

scientific article

Epithelial-mesenchymal transition and podocyte loss in diabetic kidney disease

scientific article published on October 2009

Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function

scientific article

FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy

scientific article published on 30 April 2019

Fat Burning Problem in Cystic Kidneys: an Emerging Common Mechanism of Chronic Kidney Disease

scientific article published on 23 February 2016

Fetal environment, epigenetics, and pediatric renal disease

scientific article

Fine tuning gene expression: the epigenome

scientific article

For better or worse: a niche for Notch in parietal epithelial cell activation

scientific article published on June 2013

Functional genomic annotation of genetic risk loci highlights inflammation and epithelial biology networks in CKD

scientific journal article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease

scientific article published on June 2017

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

scientific article published on 19 September 2019

Genome-Wide Association of Copy Number Polymorphisms and Kidney Function

scientific article

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Getting a notch closer to understanding diabetic kidney disease

scientific article

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

scientific article published in January 2006

Going from acute to chronic kidney injury with FoxO3

scientific article published on 06 May 2019

Human Kidney Tubule-Specific Gene Expression Based Dissection of Chronic Kidney Disease Traits

scientific article

Human and murine kidneys show gender- and species-specific gene expression differences in response to injury

scientific article

In Utero Exposure to a High-Fat Diet Programs Hepatic Hypermethylation and Gene Dysregulation and Development of Metabolic Syndrome in Male Mice

scientific article published in September 2017

Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1

scientific article published on 29 January 2020

Kick it up a notch: Notch signaling and kidney fibrosis

scientific article

Kidney cancer is characterized by aberrant methylation of tissue-specific enhancers that are prognostic for overall survival

scientific article published on 10 June 2014

Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease

scientific article published on 05 June 2019

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids

scientific article published on 12 April 2017

Ligands of purinergic receptors stimulate electrogenic H+ -transport of neutrophils

scientific article published on 01 November 1995

Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions

scientific article published in March 2005

Long-Range Chromatin Interactions in the Kidney

scientific article published on 13 February 2019

Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses

scientific article published on 10 June 2020

Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program

scientific article published on 26 August 2019

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

scientific article published in 2021

Molecular Profiling of Diabetic Mouse Kidney Reveals Novel Genes Linked to Glomerular Disease

article

Molecular mechanisms of diabetic kidney disease

scientific article

Mouse models of diabetic nephropathy

scientific article

Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy

scientific article

Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer

scientific article published on December 2016

Notch in the kidney: development and disease

scientific article published on 24 August 2011

Notch signaling in diabetic nephropathy ⬇️

scientific article published on March 5, 2012

Notch ties a knot on fistula maturation

scientific article published on 30 January 2014

Notch1 and Notch2 in Podocytes Play Differential Roles During Diabetic Nephropathy Development

scientific article

Partitioning-Defective 1a/b Depletion Impairs Glomerular and Proximal Tubule Development

scientific article

Podocytes: the Weakest Link in Diabetic Kidney Disease?

scientific article published on May 2016

Poly(ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/db mice

scientific article published in November 2006

Precision Medicine Approaches to Diabetic Kidney Disease: Tissue as an Issue

scientific article published on May 2017

Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease

scientific article published in October 2018

Repair problems in podocytes: Wnt, Notch, and glomerulosclerosis

scientific article

Role of DNA methylation in renal cell carcinoma

scientific article (publication date: 2015)

SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes

scientific article

Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets

scientific article published on 15 April 2021

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

scientific article published on 14 April 2020

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

scientific article

Sirt1-Claudin-1 crosstalk regulates renal function

scientific article published in November 2013

Smad1 as a Biomarker for Diabetic Nephropathy

scientific article published on 01 June 2008

Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice

scientific article

Sweet debate: fructose versus glucose in diabetic kidney disease

scientific article published on 29 May 2014

Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease

scientific article published on 03 November 2020

The Notch pathway in podocytes plays a role in the development of glomerular disease

scientific article

The evolving understanding of the contribution of lipid metabolism to diabetic kidney disease

scientific article published on July 2015

The hyperglycemic and hyperinsulinemic combo gives you diabetic kidney disease immediately. Focus on "Combined acute hyperglycemic and hyperinsulinemic clamp induced profibrotic and proinflammatory responses in the kidney".

scientific article published on 11 December 2013

The interdependence of renal epithelial and endothelial metabolism and cell state

scientific article published on 09 June 2020

The long noncoding RNA Tug1 connects metabolic changes with kidney disease in podocytes

scientific article published on 17 October 2016

The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury

scientific article

The next generation of therapeutics for chronic kidney disease

scientific article published on 27 May 2016

The pathogenic role of Notch activation in podocytes

The role of osteopontin in the development of albuminuria

scientific article published on May 2008

The story of Notch and chronic kidney disease

scientific article

Therapeutics for APOL1 nephropathies: putting out the fire in the podocyte

scientific article published on January 2017

Tracing the footsteps of glomerular insulin signaling in diabetic kidney disease

scientific article published on April 2011

Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags.

scientific article

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Transcriptome analysis of human diabetic kidney disease

scientific article

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

scientific article

Understanding the epigenetic syntax for the genetic alphabet in the kidney

scientific article published on 31 October 2013

Unravelling the complex genetics of common kidney diseases: from variants to mechanisms

scientific article published on 08 June 2020

Urinary Single-Cell Profiling Captures the Cellular Diversity of the Kidney

scientific article published on 02 February 2021

Validation and genomic interrogation of the MET variant rs11762213 as a predictor of adverse outcomes in clear cell renal cell carcinoma

scientific article published on 27 October 2015

Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival

scientific article

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