List of works - Marco Muzi-Falconi

14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forks

scientific article

A blooming resolvase at chromosomal fragile sites.

scientific article published in August 2013

A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1.

scientific article

Budding Yeast DNA Damage Checkpoint: A Signal Transduction-Mediated Surveillance System

Checkpoint mechanisms at the intersection between DNA damage and repair

scientific article published on 03 June 2009

Checkpoint response to DNA damage.

scientific article

Correlation between checkpoint activation and in vivo assembly of the yeast checkpoint complex Rad17-Mec3-Ddc1.

scientific article published on 2 April 2003

DNA damage checkpoint in budding yeast.

scientific article

DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.

scientific article

DNA decay and limited Rad53 activation after liquid holding of UV-treated nucleotide excision repair deficient S. cerevisiae cells

scientific article published on 01 December 2004

DNA nucleotide excision repair-dependent signaling to checkpoint activation

scientific article

Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity

scientific article

Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway

scientific article

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

scientific article

Haspin regulates Ras localization to promote Cdc24-driven mitotic depolarization

scientific article published on 23 June 2020

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

scientific article published on 17 April 2008

Mind the gap: keeping UV lesions in check.

scientific article published on 23 May 2011

Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.

scientific article

NER and DDR: classical music with new instruments.

scientific article

Non-canonical CRL4A/4B(CDT2) interacts with RAD18 to modulate post replication repair and cell survival.

scientific article

Novel DYT11 gene mutation in patients without dopaminergic deficit (SWEDD) screened for dystonia

scientific article published on 22 August 2014

Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiae

scientific article published on 01 May 1990

One-step high-throughput assay for quantitative detection of beta-galactosidase activity in intact gram-negative bacteria, yeast, and mammalian cells

scientific article published on April 2006

Overproduction and functional analysis of DNA primase subunits from yeast and mouse

scientific article published on 01 April 1992

Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint

scientific article

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex

scientific article published on 24 November 2010

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

scientific article

RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

scientific article published on January 2012

Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instability

scientific article

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair

scientific article

Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε

scientific article

Sometimes size does matter

scientific article published in July 2003

The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae

scientific article

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

scientific article

The DNA replication checkpoint response stabilizes stalled replication forks

scientific article (publication date: 2 August 2001)

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

scientific article published on 29 April 2015

To trim or not to trim: progression and control of DSB end resection

scientific article published on 29 May 2013

Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1

Yeast haspin kinase regulates polarity cues necessary for mitotic spindle positioning and is required to tolerate mitotic arrest.

scientific article

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

scientific article published on February 1996

List of works by Marco Muzi-Falconi

14-3-3 Proteins regulate exonuclease 1-dependent processing of stalled replication forks

A blooming resolvase at chromosomal fragile sites.

A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1.

Budding Yeast DNA Damage Checkpoint: A Signal Transduction-Mediated Surveillance System

Checkpoint mechanisms at the intersection between DNA damage and repair

Checkpoint response to DNA damage.

Correlation between checkpoint activation and in vivo assembly of the yeast checkpoint complex Rad17-Mec3-Ddc1.

DNA damage checkpoint in budding yeast.

DNA damage checkpoints and DNA replication controls in Saccharomyces cerevisiae.

DNA decay and limited Rad53 activation after liquid holding of UV-treated nucleotide excision repair deficient S. cerevisiae cells

DNA nucleotide excision repair-dependent signaling to checkpoint activation

Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity

Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

Haspin regulates Ras localization to promote Cdc24-driven mitotic depolarization

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

Mind the gap: keeping UV lesions in check.

Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.

NER and DDR: classical music with new instruments.

Non-canonical CRL4A/4B(CDT2) interacts with RAD18 to modulate post replication repair and cell survival.

Novel DYT11 gene mutation in patients without dopaminergic deficit (SWEDD) screened for dystonia

Nucleotide sequence and characterization of temperature-sensitive pol1 mutants of Saccharomyces cerevisiae

One-step high-throughput assay for quantitative detection of beta-galactosidase activity in intact gram-negative bacteria, yeast, and mammalian cells

Overproduction and functional analysis of DNA primase subunits from yeast and mouse

Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instability

Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair

Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε

Sometimes size does matter

The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae

The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

The DNA replication checkpoint response stabilizes stalled replication forks

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.

To trim or not to trim: progression and control of DSB end resection

Yeast Rev1 is cell cycle regulated, phosphorylated in response to DNA damage and its binding to chromosomes is dependent upon MEC1

Yeast haspin kinase regulates polarity cues necessary for mitotic spindle positioning and is required to tolerate mitotic arrest.

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.