List of works - John C Voss

1,3-Dinitrobenzene metabolism and GSH depletion

scientific article published in March 2002

A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta

scientific article published on 12 August 2018

A Metal-Free Method for Producing MRI Contrast at Amyloid-β.

scientific article published on 26 November 2016

A continuous spectrophotometric assay for simultaneous measurement of calcium uptake and ATP hydrolysis in sarcoplasmic reticulum

scientific article published on 01 May 1995

A differential association of Apolipoprotein E isoforms with the amyloid-β oligomer in solution.

scientific article

Analysis of lipid phase behavior and protein conformational changes in nanolipoprotein particles upon entrapment in sol-gel-derived silica.

scientific article published on 6 August 2014

Apolipoprotein A-I assumes a "looped belt" conformation on reconstituted high density lipoprotein

scientific article published on 11 May 2006

Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325.

scientific article published in November 1997

Bridging across length scales: multi-scale ordering of supported lipid bilayers via lipoprotein self-assembly and surface patterning.

scientific article

C-terminal interactions of apolipoprotein E4 respond to the postprandial state.

scientific article

Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents

scientific article

Case method teaching: an effective approach to integrate the basic and clinical sciences in the preclinical medical curriculum

scientific article published in September 2009

Characterization of a conformationally sensitive TOAC spin-labeled substance P.

scientific article

Characterization of de novo synthesized GPCRs supported in nanolipoprotein discs

scientific article

Characterization of structural changes in vimentin bearing an epidermolysis bullosa simplex-like mutation using site-directed spin labeling and electron paramagnetic resonance.

scientific article

Characterization of the biochemical and biophysical properties of the Saccharomyces cerevisiae phosphate transporter Pho89.

scientific article published on 12 June 2013

Conservation of apolipoprotein A-I's central domain structural elements upon lipid association on different high-density lipoprotein subclasses.

scientific article published on 17 September 2013

Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains.

scientific article published on January 2007

Double electron-electron resonance probes Ca²⁺-induced conformational changes and dimerization of recoverin.

scientific article published on 16 August 2013

EPR assessment of protein sites for incorporation of Gd(III) MRI contrast labels

scientific article

Effects of melittin on molecular dynamics and Ca-ATPase activity in sarcoplasmic reticulum membranes: time-resolved optical anisotropy

scientific article published in July 1991

Electron paramagnetic resonance analysis of the vimentin tail domain reveals points of order in a largely disordered region and conformational adaptation upon filament assembly ⬇️

scientific article published on January 1, 2013

Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli.

scientific article published in May 1995

Expression and purification of cysteine introduced recombinant saporin.

scientific article

Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity

scientific article

Head and rod 1 interactions in vimentin: identification of contact sites, structure, and changes with phosphorylation using site-directed spin labeling and electron paramagnetic resonance

scientific article published on 31 December 2008

Helix packing in polytopic membrane proteins: the lactose permease of Escherichia coli ⬇️

scientific article published on August 1, 1997

Helix packing in the lactose permease determined by metal-nitroxide interaction

scientific article published in January 1998

Helix packing in the lactose permease of Escherichia coli: distances between site-directed nitroxides and a lanthanide

scientific article published in March 2001

How to Study Intermediate Filaments in Atomic Detail

scientific article

Imaging apolipoprotein AI in vivo ⬇️

scientific article published on January 24, 2011

Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy.

scientific article published on 24 December 2008

Lipid-induced extension of apolipoprotein E helix 4 correlates with low density lipoprotein receptor binding ability.

scientific article published in November 2006

Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways.

scientific article

Mechanism of Ca-ATPase inhibition by melittin in skeletal sarcoplasmic reticulum

scientific article published on 01 January 1995

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins ⬇️

scientific article published on August 6, 2010

Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms

scientific article published on 01 August 2005

Molecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function

scientific article

Molecular dynamics simulation of dipalmitoylphosphatidylcholine modified with a MTSL nitroxide spin label in a lipid membrane

scientific article published on 13 August 2013

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation

scientific article

Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins.

scientific article published on 30 October 2012

Probing the binding pocket and endocytosis of a G protein-coupled receptor in live cells reported by a spin-labeled substance P agonist

scientific article

Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure

scientific article

Protein and lipid rotational dynamics in cardiac and skeletal sarcoplasmic reticulum detected by EPR and phosphorescence anisotropy

scientific article published on 01 September 1993

Proximity between periplasmic loops in the lactose permease of Escherichia coli as determined by site-directed spin labeling

scientific article published on 01 March 1999

Proximity of helices VIII (Ala273) and IX (Met299) in the lactose permease of Escherichia coli.

scientific article published in April 1998

Real-time observation of coiled-coil domains and subunit assembly in intermediate filaments.

scientific article

Secondary structure changes in ApoA-I Milano (R173C) are not accompanied by a decrease in protein stability or solubility

scientific article

Site-directed spin labeling and electron paramagnetic resonance determination of vimentin head domain structure.

scientific article

Site-directed spin labeling demonstrates that transmembrane domain XII in the lactose permease of Escherichia coli is an alpha-helix

scientific article

Site-directed spin-labeling of transmembrane domain VII and the 4B1 antibody epitope in the lactose permease of Escherichia coli.

scientific article published in December 1997

Site-specific insertion of spin-labeled L-amino acids in Xenopus oocytes.

scientific article

Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.

scientific article

Spectroscopic Characterization of Structural Changes in Membrane Scaffold Proteins Entrapped within Mesoporous Silica Gel Monoliths

scientific article published on 20 April 2015

Stoichiometry of reconstituted high-density lipoproteins in the hydrated state determined by photon antibunching

scientific article

Structural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1 ⬇️

scientific article published on October 25, 2010

Structural characterization of human vimentin rod 1 and the sequencing of assembly steps in intermediate filament formation in vitro using site-directed spin labeling and electron paramagnetic resonance

scientific article published on July 2004

Structural modeling of dual-affinity purified Pho84 phosphate transporter

scientific article published in December 2004

Structure of apolipoprotein A-I N terminus on nascent high density lipoproteins.

scientific article

Sulfhydryl oxidation of mutants with cysteine in place of acidic residues in the lactose permease

scientific article published in June 1998

Superhydrophobic bowl-like SERS substrates patterned from CMOS sensors for extracellular vesicle characterization

scientific article published on 01 October 2020

Synthesis and study of 2-amino-7-bromofluorenes modified with nitroxides and their precursors as dual anti-amyloid and antioxidant active compounds.

scientific article published on 3 February 2011

The "beta-clasp" model of apolipoprotein A-I--a lipid-free solution structure determined by electron paramagnetic resonance spectroscopy.

scientific article

The C-terminal domain of apolipoprotein A-I contains a lipid-sensitive conformational trigger

scientific article published in June 2003

The bipolar assembly domain of the mitotic motor kinesin-5

scientific article

The future of neurodegenerative diseases: emerging targets, treatments and technologies

scientific article published in September 2012

The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide

scientific article

The physical mechanism of calcium pump regulation in the heart

scientific article published in July 1994

The secondary structure of apolipoprotein A‐I on 9.6‐nm reconstituted high‐density lipoprotein determined by EPR spectroscopy ⬇️

scientific article published on June 10, 2013

The use of spin-labeled ligands as biophysical probes to report real-time endocytosis of G protein-coupled receptors in living cells.

scientific article published on 4 May 2004

Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport.

scientific article

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358).

scientific article

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).

scientific article published in December 1995

VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation.

scientific article

List of works by John C Voss

1,3-Dinitrobenzene metabolism and GSH depletion

A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta

A Metal-Free Method for Producing MRI Contrast at Amyloid-β.

A continuous spectrophotometric assay for simultaneous measurement of calcium uptake and ATP hydrolysis in sarcoplasmic reticulum

A differential association of Apolipoprotein E isoforms with the amyloid-β oligomer in solution.

Analysis of lipid phase behavior and protein conformational changes in nanolipoprotein particles upon entrapment in sol-gel-derived silica.

Apolipoprotein A-I assumes a "looped belt" conformation on reconstituted high density lipoprotein

Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325.

Bridging across length scales: multi-scale ordering of supported lipid bilayers via lipoprotein self-assembly and surface patterning.

C-terminal interactions of apolipoprotein E4 respond to the postprandial state.

Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents

Case method teaching: an effective approach to integrate the basic and clinical sciences in the preclinical medical curriculum

Characterization of a conformationally sensitive TOAC spin-labeled substance P.

Characterization of de novo synthesized GPCRs supported in nanolipoprotein discs

Characterization of structural changes in vimentin bearing an epidermolysis bullosa simplex-like mutation using site-directed spin labeling and electron paramagnetic resonance.

Characterization of the biochemical and biophysical properties of the Saccharomyces cerevisiae phosphate transporter Pho89.

Conservation of apolipoprotein A-I's central domain structural elements upon lipid association on different high-density lipoprotein subclasses.

Describing the structure and assembly of protein filaments by EPR spectroscopy of spin-labeled side chains.

Double electron-electron resonance probes Ca²⁺-induced conformational changes and dimerization of recoverin.

EPR assessment of protein sites for incorporation of Gd(III) MRI contrast labels

Effects of melittin on molecular dynamics and Ca-ATPase activity in sarcoplasmic reticulum membranes: time-resolved optical anisotropy

Electron paramagnetic resonance analysis of the vimentin tail domain reveals points of order in a largely disordered region and conformational adaptation upon filament assembly ⬇️

Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli.

Expression and purification of cysteine introduced recombinant saporin.

Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity

Head and rod 1 interactions in vimentin: identification of contact sites, structure, and changes with phosphorylation using site-directed spin labeling and electron paramagnetic resonance

Helix packing in polytopic membrane proteins: the lactose permease of Escherichia coli ⬇️

Helix packing in the lactose permease determined by metal-nitroxide interaction

Helix packing in the lactose permease of Escherichia coli: distances between site-directed nitroxides and a lanthanide

How to Study Intermediate Filaments in Atomic Detail

Imaging apolipoprotein AI in vivo ⬇️

Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy.

Lipid-induced extension of apolipoprotein E helix 4 correlates with low density lipoprotein receptor binding ability.

Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways.

Mechanism of Ca-ATPase inhibition by melittin in skeletal sarcoplasmic reticulum

Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins ⬇️

Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms

Molecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function

Molecular dynamics simulation of dipalmitoylphosphatidylcholine modified with a MTSL nitroxide spin label in a lipid membrane

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation

Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins.

Probing the binding pocket and endocytosis of a G protein-coupled receptor in live cells reported by a spin-labeled substance P agonist

Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure

Protein and lipid rotational dynamics in cardiac and skeletal sarcoplasmic reticulum detected by EPR and phosphorescence anisotropy

Proximity between periplasmic loops in the lactose permease of Escherichia coli as determined by site-directed spin labeling

Proximity of helices VIII (Ala273) and IX (Met299) in the lactose permease of Escherichia coli.

Real-time observation of coiled-coil domains and subunit assembly in intermediate filaments.

Secondary structure changes in ApoA-I Milano (R173C) are not accompanied by a decrease in protein stability or solubility

Site-directed spin labeling and electron paramagnetic resonance determination of vimentin head domain structure.

Site-directed spin labeling demonstrates that transmembrane domain XII in the lactose permease of Escherichia coli is an alpha-helix

Site-directed spin-labeling of transmembrane domain VII and the 4B1 antibody epitope in the lactose permease of Escherichia coli.

Site-specific insertion of spin-labeled L-amino acids in Xenopus oocytes.

Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.

Spectroscopic Characterization of Structural Changes in Membrane Scaffold Proteins Entrapped within Mesoporous Silica Gel Monoliths

Stoichiometry of reconstituted high-density lipoproteins in the hydrated state determined by photon antibunching

Structural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1 ⬇️

Structural characterization of human vimentin rod 1 and the sequencing of assembly steps in intermediate filament formation in vitro using site-directed spin labeling and electron paramagnetic resonance

Structural modeling of dual-affinity purified Pho84 phosphate transporter

Structure of apolipoprotein A-I N terminus on nascent high density lipoproteins.

Sulfhydryl oxidation of mutants with cysteine in place of acidic residues in the lactose permease

Superhydrophobic bowl-like SERS substrates patterned from CMOS sensors for extracellular vesicle characterization

Synthesis and study of 2-amino-7-bromofluorenes modified with nitroxides and their precursors as dual anti-amyloid and antioxidant active compounds.

The "beta-clasp" model of apolipoprotein A-I--a lipid-free solution structure determined by electron paramagnetic resonance spectroscopy.

The C-terminal domain of apolipoprotein A-I contains a lipid-sensitive conformational trigger

The bipolar assembly domain of the mitotic motor kinesin-5

The future of neurodegenerative diseases: emerging targets, treatments and technologies

The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide

The physical mechanism of calcium pump regulation in the heart

The secondary structure of apolipoprotein A‐I on 9.6‐nm reconstituted high‐density lipoprotein determined by EPR spectroscopy ⬇️

The use of spin-labeled ligands as biophysical probes to report real-time endocytosis of G protein-coupled receptors in living cells.

Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport.

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358).

Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).

VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation.