List of works - Alexandra Gaspar

4-Oxo-N-phenyl-4H-chromene-2-carboxamide and of a new polymorph of 7-methoxy-4-oxo-N-p-tolyl-4H-chromene-2-carboxamide and its hemihydrate

A comparison of the structures of some 2- and 3-substituted chromone derivatives: a structural study on the importance of the secondary carboxamide backbone for the inhibitory activity of MAO-B.

scientific article

Accelerating lead optimization of chromone carboxamide scaffold throughout microwave-assisted organic synthesis

article

Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress

scientific article published in 2012

Antioxidant phenolic esters with potential anticancer activity: A Raman spectroscopy study

Antioxidant phenolic esters with potential anticancer activity: solution equilibria studied by Raman spectroscopy

Antioxidant versus cytotoxic properties of hydroxycinnamic acid derivatives - a new paradigm in phenolic research.

scientific article published on March 2008

Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors ⬇️

scientific article published on December 5, 2010

Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances

scientific article published on 24 May 2017

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

scientific article published on July 2011

Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.

scientific article published on 27 March 2010

Chromone: a valid scaffold in medicinal chemistry

scientific article

Co-cultivation of Synechocystis salina and Pseudokirchneriella subcapitata under varying phosphorus concentrations evidences an allelopathic competition scenario

article

Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors

scientific article published on November 2012

Crystal structures of ethyl 6-(4-methyl-phen-yl)-4-oxo-4H-chromene-2-carboxyl-ate and ethyl 6-(4-fluoro-phen-yl)-4-oxo-4H-chromene-2-carboxyl-ate

scientific article

Cytotoxic and COX-2 Inhibition Properties of Hydroxycinnamic Derivatives

Dietary Phenolic Acids and Derivatives. Evaluation of the Antioxidant Activity of Sinapic Acid and Its Alkyl Esters

Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors.

scientific article published on 31 May 2016

Discovery of novel A3 adenosine receptor ligands based on chromone scaffold

scientific article

Discovery of the first A1 adenosine receptor ligand based on the chromone scaffold

article

Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry

scientific article published on 01 February 2015

Exploring nature profits: development of novel and potent lipophilic antioxidants based on galloyl-cinnamic hybrids

scientific article

Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes

scientific article

Hydroxycinnamic acid antioxidants: an electrochemical overview

scientific article published on 16 July 2013

Improved Synthesis of 3-(Aminoaryl)coumarins

In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-γ-pyrone skeleton

scientific article

Influence of Hydroxypropyl-β-Cyclodextrin on the Photostability of Fungicide Pyrimethanil

Navigating in chromone chemical space: discovery of novel and distinct A3 adenosine receptor ligands

article

New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives

scientific article

Parkinson's Disease Management. Part II- Discovery of MAO-B Inhibitors Based on Nitrogen Heterocycles and Analogues

scientific article published on January 1, 2012

Phenolic esters with potential anticancer activity - the structural variable

scientific article published on 06 March 2007

Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold

article

Structural characterization of some N-phenyl-4-oxo-4H-2-chromone carboxamides

scientific article published on 8 May 2013

Structural elucidation of a series of 6-methyl-3-carboxamidocoumarins

scientific article published on 10 November 2016

Structural elucidation of a series of benzamide derivatives

scientific article published on 18 November 2017

Structure of 7-hy-droxy-3-(2-meth-oxy-phen-yl)-2-tri-fluoro-meth-yl-4H-chromen-4-one

scientific article

Study on the volatility of halogenated fluorenes

Synthesis and NMR studies of novel chromone‐2‐carboxamide derivatives ⬇️

scientific article published on February 14, 2013

Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins

scientific article published on 22 August 2013

Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates

scientific article published on 21 December 2010

Synthesis of 6-aryl/heteroaryl-4-oxo-4 H -chromene-2-carboxylic ethyl ester derivatives

Synthesis, spectroscopic characterization and X-ray structure of novel 7-methoxy-4-oxo-N-phenyl-4H-chromene-2-carboxamides

Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives

scientific article published in January 2013

Towards the Discovery of a Novel Class of Monoamine Oxidase Inhibitors: Structure-Property-Activity and Docking Studies on Chromone Amides

article

List of works by Alexandra Gaspar

4-Oxo-N-phenyl-4H-chromene-2-carboxamide and of a new polymorph of 7-methoxy-4-oxo-N-p-tolyl-4H-chromene-2-carboxamide and its hemihydrate

A comparison of the structures of some 2- and 3-substituted chromone derivatives: a structural study on the importance of the secondary carboxamide backbone for the inhibitory activity of MAO-B.

Accelerating lead optimization of chromone carboxamide scaffold throughout microwave-assisted organic synthesis

Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress

Antioxidant phenolic esters with potential anticancer activity: A Raman spectroscopy study

Antioxidant phenolic esters with potential anticancer activity: solution equilibria studied by Raman spectroscopy

Antioxidant versus cytotoxic properties of hydroxycinnamic acid derivatives - a new paradigm in phenolic research.

Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors ⬇️

Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.

Chromone: a valid scaffold in medicinal chemistry

Co-cultivation of Synechocystis salina and Pseudokirchneriella subcapitata under varying phosphorus concentrations evidences an allelopathic competition scenario

Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors

Crystal structures of ethyl 6-(4-methyl-phen-yl)-4-oxo-4H-chromene-2-carboxyl-ate and ethyl 6-(4-fluoro-phen-yl)-4-oxo-4H-chromene-2-carboxyl-ate

Cytotoxic and COX-2 Inhibition Properties of Hydroxycinnamic Derivatives

Dietary Phenolic Acids and Derivatives. Evaluation of the Antioxidant Activity of Sinapic Acid and Its Alkyl Esters

Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors.

Discovery of novel A3 adenosine receptor ligands based on chromone scaffold

Discovery of the first A1 adenosine receptor ligand based on the chromone scaffold

Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry

Exploring nature profits: development of novel and potent lipophilic antioxidants based on galloyl-cinnamic hybrids

Furvina inhibits the 3-oxo-C12-HSL-based quorum sensing system of Pseudomonas aeruginosa and QS-dependent phenotypes

Hydroxycinnamic acid antioxidants: an electrochemical overview

Improved Synthesis of 3-(Aminoaryl)coumarins

In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-γ-pyrone skeleton

Influence of Hydroxypropyl-β-Cyclodextrin on the Photostability of Fungicide Pyrimethanil

Navigating in chromone chemical space: discovery of novel and distinct A3 adenosine receptor ligands

New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives

Parkinson's Disease Management. Part II- Discovery of MAO-B Inhibitors Based on Nitrogen Heterocycles and Analogues

Phenolic esters with potential anticancer activity - the structural variable

Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold

Structural characterization of some N-phenyl-4-oxo-4H-2-chromone carboxamides

Structural elucidation of a series of 6-methyl-3-carboxamidocoumarins

Structural elucidation of a series of benzamide derivatives

Structure of 7-hy-droxy-3-(2-meth-oxy-phen-yl)-2-tri-fluoro-meth-yl-4H-chromen-4-one

Study on the volatility of halogenated fluorenes

Synthesis and NMR studies of novel chromone‐2‐carboxamide derivatives ⬇️

Synthesis and adenosine receptors binding affinities of a series of 3-arylcoumarins

Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates

Synthesis of 6-aryl/heteroaryl-4-oxo-4 H -chromene-2-carboxylic ethyl ester derivatives

Synthesis, spectroscopic characterization and X-ray structure of novel 7-methoxy-4-oxo-N-phenyl-4H-chromene-2-carboxamides

Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives

Towards the Discovery of a Novel Class of Monoamine Oxidase Inhibitors: Structure-Property-Activity and Docking Studies on Chromone Amides