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List of works by Tiago Silva

Alzheimer's disease and antioxidant therapy: how long how far?

scientific article published on January 2013

Alzheimer's disease, cholesterol, and statins: the junctions of important metabolic pathways

scientific article published on 20 December 2012

Alzheimer's disease, enzyme targets and drug discovery struggles: from natural products to drug prototypes

scientific article published on 13 April 2014

Antioxidant therapy: still in search of the 'magic bullet'.

scientific article

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents

scientific article published on 17 April 2019

Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid

scientific article published on 01 November 2019

Biology-oriented development of novel lipophilic antioxidants with neuroprotective activity

article

Caffeic Acid Alkyl Amide Derivatives Ameliorate Oxidative Stress and Modulate ERK1/2 and AKT Signaling Pathways in a Rat Model of Diabetic Retinopathy

scientific article published on 04 December 2019

Caffeic acid derivatives, analogs and applications: a patent review (2009-2013).

scientific article published on 04 October 2014

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors

scientific article published on July 2011

Correction to Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors

scientific article published on 29 May 2018

Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?

scientific article published on 28 July 2017

Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents

scientific article published on 27 April 2017

Development of Blood-Brain Barrier Permeable Nitrocatechol-Based Catechol O-Methyltransferase Inhibitors with Reduced Potential for Hepatotoxicity

scientific article published on 27 July 2016

Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors.

scientific article published on 31 May 2016

Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold

scientific article published on 28 July 2016

Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry

scientific article published on 01 February 2015

Effects of chlorophenoxy herbicides and their main transformation products on DNA damage and acetylcholinesterase activity

scientific article published on 27 March 2014

Exploring cinnamic acid scaffold: development of promising neuroprotective lipophilic antioxidants

article

Exploring nature profits: development of novel and potent lipophilic antioxidants based on galloyl-cinnamic hybrids

scientific article

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors.

scientific article

Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic Analogues

scientific article published on 02 December 2019

Lessons from black pepper: piperine and derivatives thereof

scientific article

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells

scientific article published on 28 April 2011

Long Chain Alkyl Esters of Hydroxycinnamic Acids as Promising Anticancer Agents: Selective Induction of Apoptosis in Cancer Cells

scientific article published on 18 July 2017

Microencapsulation of caffeic acid phenethyl ester and caffeic acid phenethyl amide by inclusion in hydroxypropyl-β-cyclodextrin.

scientific article published on 16 February 2018

Modulation of ERK1/2 and Akt Pathways Involved in the Neurotrophic Action of Caffeic Acid Alkyl Esters

NO and HNO donors, nitrones, and nitroxides: Past, present, and future

scientific article

New insights into the antioxidant activity of hydroxycinnamic and hydroxybenzoic systems: spectroscopic, electrochemistry, and cellular studies

scientific article published on 14 October 2014

Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors

scientific article published on 24 January 2019

Plant derived and dietary phenolic antioxidants: anticancer properties.

scientific article published on 18 March 2015

Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6

scientific article published on 04 February 2019

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