List of works - Stefan Scholz

17-alpha-ethinylestradiol affects reproduction, sexual differentiation and aromatase gene expression of the medaka (Oryzias latipes).

scientific article published in October 2000

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

scientific article

APPLICABILITY OF THE FISH EMBRYO ACUTE TOXICITY (FET) TEST (OECD 236) IN THE REGULATORY CONTEXT OF REACH.

scientific article published on 11 December 2017

Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies

scientific article published on 12 July 2011

Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line

scientific article

Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians--screening for estrogen, androgen and thyroid hormone disruption.

scientific article

An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos

scientific article published in PLoS ONE

An ecotoxicological view on neurotoxicity assessment

scientific article published on 14 December 2018

Analysis of estrogenic effects by quantification of green fluorescent protein in juvenile fish of a transgenic medaka

scientific article published in October 2005

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

scientific article published on 27 September 2014

Automated morphological feature assessment for zebrafish embryo developmental toxicity screens

article

Bacterial lipopolysaccharides induce genes involved in the innate immune response in embryos of the zebrafish (Danio rerio).

scientific article published on 14 March 2007

Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays

scientific article published on 26 December 2013

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment

scientific article published on 08 August 2019

Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy

scientific article published on 16 July 2018

Comparative Assessment of the Sensitivity of Fish Early-Life Stage, Daphnia, and Algae Tests to the Chronic Ecotoxicity of Xenobiotics: Perspectives for Alternatives to Animal Testing

scientific article published on 18 December 2019

Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos

scientific article published on 8 May 2015

DRomics: A Turnkey Tool to Support the Use of the Dose-Response Framework for Omics Data in Ecological Risk Assessment

scientific article published on 04 December 2018

Developing a list of reference chemicals for testing alternatives to whole fish toxicity tests.

scientific article published on 22 August 2008

Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test

scientific article published on 30 August 2016

Di-myo-inositol-1, 1′-phosphate: A new inositol phosphate isolated fromPyrococcus woesei

scientific article published on 01 July 1992

Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae

scientific article published on 12 January 2007

Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects.

scientific article published on 30 June 2015

Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos.

scientific article published on 19 May 2014

Effects of endocrine disrupters on sexual, gonadal development in fish

scientific article published on 10 August 2009

Endocrine, teratogenic and neurotoxic effects of cyanobacteria detected by cellular in vitro and zebrafish embryos assays

scientific article

Evaluation of health risks of nano- and microparticles

article

Extensive review of fish embryo acute toxicities for the prediction of GHS acute systemic toxicity categories

scientific article

Fish embryo toxicity test: identification of compounds with weak toxicity and analysis of behavioral effects to improve prediction of acute toxicity for neurotoxic compounds

scientific article published on 15 May 2015

Fish embryos as alternative models for drug safety evaluation

From the exposome to mechanistic understanding of chemical-induced adverse effects

scientific article

Gene expression analysis in zebrafish embryos: a potential approach to predict effect concentrations in the fish early life stage test.

scientific article published in September 2009

Germ cell-less expression in medaka (Oryzias latipes).

scientific article published in January 2004

Hormonal induction and stability of monosex populations in the medaka (Oryzias latipes): expression of sex-specific marker genes

scientific article published on 30 April 2003

Identification and Characterization of Androgen-Responsive Genes in Zebrafish Embryos

scientific article published on 26 August 2015

Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems.

scientific article

In Response: Quantitative adverse outcome pathways for prediction of adverse effects-An academic perspective

article

Induction of CYP1A in Primary Cultures of Rainbow Trout (Oncorhynchus mykiss) Liver Cells: Concentration–Response Relationships of Four Model Substances

article

Induction of vitellogenin in vivo and in vitro in the model teleost medaka (Oryzias latipes): comparison of gene expression and protein levels

scientific article published in April 2004

Meta-Analysis of Fish Early Life Stage Tests - Association of Toxic Ratios and Acute-To-Chronic Ratios with Modes of Action

scientific article published on 19 January 2018

Mixture toxicity revisited from a toxicogenomic perspective

scientific article published on 27 February 2012

Mixtures of organic micropollutants exacerbated in vitro neurotoxicity of prymnesins and contributed to aquatic toxicity during a toxic algal bloom

scientific article published on 6 September 2024

Molecular biomarkers of endocrine disruption in small model fish

scientific article published on 21 June 2008

Naringenin-type flavonoids show different estrogenic effects in mammalian and teleost test systems.

scientific article

OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing

scientific article published on 27 May 2014

Of fine powders, hardmetals, hazard and health risk

article

Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

article

Retinoid-like activity and teratogenic effects of cyanobacterial exudates

scientific article published on 6 July 2014

Species-specific developmental toxicity in rats and rabbits: generation of a reference compound list for development of alternative testing approaches

scientific article published on 31 January 2018

Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway.

scientific article published on 10 June 2009

The EU chemicals strategy for sustainability: an opportunity to develop new approaches for hazard and risk assessment

scientific article published in 2022

The biosynthesis pathway of di-myo-inositol-1,1′-phosphate in Pyrococcus woesei

scientific article published in 1998

The role of chemical speciation, chemical fractionation and calcium disruption in manganese-induced developmental toxicity in zebrafish (Danio rerio) embryos

scientific article published on 10 July 2015

The role of cyp1a and heme oxygenase 1 gene expression for the toxicity of 3,4-dichloroaniline in zebrafish (Danio rerio) embryos

scientific article published on 23 October 2007

The zebrafish embryo model in environmental risk assessment--applications beyond acute toxicity testing

scientific article published on 25 June 2008

The zebrafish has become an attractive model organism in many areas of research ranging from basic developmental biology to applied toxicology.

scientific article published on 2 February 2012

Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro

scientific article

Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression

scientific article

Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine

scientific article published on 12 January 2012

Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals

scientific article published on 9 May 2013

Transient overexpression of adh8a increases allyl alcohol toxicity in zebrafish embryos

scientific article

Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes

scientific article

Yolk/water partitioning of neutral organic compounds in the model organism Danio rerio

scientific article published on 07 May 2020

Zebrafish biosensor for toxicant induced muscle hyperactivity

scientific article

Zebrafish embryo and acute fish toxicity test show similar sensitivity for narcotic compounds

article

Zebrafish embryo tolerance to environmental stress factors-Concentration-dose response analysis of oxygen limitation, pH, and UV-light irradiation

scientific article

Zebrafish embryos as an alternative model for screening of drug-induced organ toxicity

scientific article published on 30 March 2013

Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations

scientific article published on 25 June 2011

List of works by Stefan Scholz

17-alpha-ethinylestradiol affects reproduction, sexual differentiation and aromatase gene expression of the medaka (Oryzias latipes).

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment

APPLICABILITY OF THE FISH EMBRYO ACUTE TOXICITY (FET) TEST (OECD 236) IN THE REGULATORY CONTEXT OF REACH.

Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies

Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line

Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians--screening for estrogen, androgen and thyroid hormone disruption.

An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos

An ecotoxicological view on neurotoxicity assessment

Analysis of estrogenic effects by quantification of green fluorescent protein in juvenile fish of a transgenic medaka

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

Automated morphological feature assessment for zebrafish embryo developmental toxicity screens

Bacterial lipopolysaccharides induce genes involved in the innate immune response in embryos of the zebrafish (Danio rerio).

Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment

Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy

Comparative Assessment of the Sensitivity of Fish Early-Life Stage, Daphnia, and Algae Tests to the Chronic Ecotoxicity of Xenobiotics: Perspectives for Alternatives to Animal Testing

Comparative analysis of goitrogenic effects of phenylthiourea and methimazole in zebrafish embryos

DRomics: A Turnkey Tool to Support the Use of the Dose-Response Framework for Omics Data in Ecological Risk Assessment

Developing a list of reference chemicals for testing alternatives to whole fish toxicity tests.

Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test

Di-myo-inositol-1, 1′-phosphate: A new inositol phosphate isolated fromPyrococcus woesei

Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae

Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects.

Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos.

Effects of endocrine disrupters on sexual, gonadal development in fish

Endocrine, teratogenic and neurotoxic effects of cyanobacteria detected by cellular in vitro and zebrafish embryos assays

Evaluation of health risks of nano- and microparticles

Extensive review of fish embryo acute toxicities for the prediction of GHS acute systemic toxicity categories

Fish embryo toxicity test: identification of compounds with weak toxicity and analysis of behavioral effects to improve prediction of acute toxicity for neurotoxic compounds

Fish embryos as alternative models for drug safety evaluation

From the exposome to mechanistic understanding of chemical-induced adverse effects

Gene expression analysis in zebrafish embryos: a potential approach to predict effect concentrations in the fish early life stage test.

Germ cell-less expression in medaka (Oryzias latipes).

Hormonal induction and stability of monosex populations in the medaka (Oryzias latipes): expression of sex-specific marker genes

Identification and Characterization of Androgen-Responsive Genes in Zebrafish Embryos

Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems.

In Response: Quantitative adverse outcome pathways for prediction of adverse effects-An academic perspective

Induction of CYP1A in Primary Cultures of Rainbow Trout (Oncorhynchus mykiss) Liver Cells: Concentration–Response Relationships of Four Model Substances

Induction of vitellogenin in vivo and in vitro in the model teleost medaka (Oryzias latipes): comparison of gene expression and protein levels

Meta-Analysis of Fish Early Life Stage Tests - Association of Toxic Ratios and Acute-To-Chronic Ratios with Modes of Action

Mixture toxicity revisited from a toxicogenomic perspective

Mixtures of organic micropollutants exacerbated in vitro neurotoxicity of prymnesins and contributed to aquatic toxicity during a toxic algal bloom

Molecular biomarkers of endocrine disruption in small model fish

Naringenin-type flavonoids show different estrogenic effects in mammalian and teleost test systems.

OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing

Of fine powders, hardmetals, hazard and health risk

Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

Retinoid-like activity and teratogenic effects of cyanobacterial exudates

Species-specific developmental toxicity in rats and rabbits: generation of a reference compound list for development of alternative testing approaches

Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway.

The EU chemicals strategy for sustainability: an opportunity to develop new approaches for hazard and risk assessment

The biosynthesis pathway of di-myo-inositol-1,1′-phosphate in Pyrococcus woesei

The role of chemical speciation, chemical fractionation and calcium disruption in manganese-induced developmental toxicity in zebrafish (Danio rerio) embryos

The role of cyp1a and heme oxygenase 1 gene expression for the toxicity of 3,4-dichloroaniline in zebrafish (Danio rerio) embryos

The zebrafish embryo model in environmental risk assessment--applications beyond acute toxicity testing

The zebrafish has become an attractive model organism in many areas of research ranging from basic developmental biology to applied toxicology.

Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro

Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression

Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine

Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals

Transient overexpression of adh8a increases allyl alcohol toxicity in zebrafish embryos

Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes

Yolk/water partitioning of neutral organic compounds in the model organism Danio rerio

Zebrafish biosensor for toxicant induced muscle hyperactivity

Zebrafish embryo and acute fish toxicity test show similar sensitivity for narcotic compounds

Zebrafish embryo tolerance to environmental stress factors-Concentration-dose response analysis of oxygen limitation, pH, and UV-light irradiation

Zebrafish embryos as an alternative model for screening of drug-induced organ toxicity

Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations