List of works by Ippei Shimizu

A crucial role for adipose tissue p53 in the regulation of insulin resistance

scientific article published on 30 August 2009

A role for circadian clock in metabolic disease.

scientific article published on 18 February 2016

Adipose tissue inflammation in diabetes and heart failure

scientific article published on 29 October 2012

Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice

scientific article published on 30 January 2012

Amlodipine Inhibits Vascular Cell Senescence and Protects Against Atherogenesis Through the Mechanism Independent of Calcium Channel Blockade.

scientific article published on 20 April 2018

An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease

scientific article

Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy.

scientific article

Boysenberry polyphenol inhibits endothelial dysfunction and improves vascular health

scientific article published in PLoS ONE

Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway

scientific article published on 3 May 2012

Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure

scientific article published on 22 June 2009

Catecholamine-Induced Senescence of Endothelial Cells and Bone Marrow Cells Promotes Cardiac Dysfunction in Mice

scientific article published on 23 May 2018

Cellular Senescence in Arterial Diseases

scientific article published on 08 January 2020

Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes

scientific article

DNA damage response and metabolic disease.

scientific article

Delayed enhancement cardiovascular magnetic resonance as a novel technique to predict cardiac events in dilated cardiomyopathy patients

scientific article published on 29 January 2009

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

scientific article published on 19 April 2010

Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture

scientific article published on 27 May 2016

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity

scientific article published on 01 September 2018

Haploinsufficiency of akt1 prolongs the lifespan of mice

scientific article

Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway.

scientific article published on 3 August 2017

Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.

scientific article published on 22 May 2014

Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis

scientific article

Maintenance of Subcutaneous Fat Homeostasis Improves Systemic Metabolic Dysfunction in Obesity.

scientific article published in December 2015

Metabolomic Analysis in Heart Failure

scientific article published on 8 December 2017

Notch signaling regulates the lifespan of vascular endothelial cells via a p16-dependent pathway

scientific article

Pathological role of adipose tissue dysfunction in cardio-metabolic disorders.

scientific article published on 27 April 2015

Physiological and pathological cardiac hypertrophy.

scientific article published on June 2016

Progerin impairs vascular smooth muscle cell growth via the DNA damage response pathway.

scientific article published on 7 March 2017

Role of the central nervous system and adipose tissue BDNF/TrkB axes in metabolic regulation ⬇️

scientific article

Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury

scientific article published on 2 December 2015

Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity

scientific article published on 01 October 2013

Vascular remodeling mediated by Angptl2 produced from perivascular adipose tissue

scientific article published on 23 March 2013

p53-Induced inflammation exacerbates cardiac dysfunction during pressure overload.

scientific article published on 6 June 2015

p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure

scientific article published on January 2012

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

scientific article published in Nature

p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.

scientific article

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