List of works - Lucia Tamborini

3-Carboxy-pyrazolinalanine as a new scaffold for developing potent and selective NMDA receptor antagonists

scientific article

A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles

A Regioselective Route to 5-Substituted Isoxazole- and Isoxazoline-3-phosphonates

A bifurcated pathway to thiazoles and imidazoles using a modular flow microreactor

scientific article

A highly efficient flow reactor process for the synthesis of N-Boc-3,4-dehydro-l-proline methyl ester

A new chemoenzymatic approach to the synthesis of Latanoprost and Bimatoprost

scholarly article by Martina Letizia Contente et al published April 2015 in Journal of Molecular Catalysis B: Enzymatic

A novel simplified synthesis of acivicin

A regioselective route to 5-substituted pyrazole- and pyrazoline-3-phosphonic acids and esters

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities ⬇️

scientific article published on 29 June 2020

An efficient continuous flow process for the synthesis of a non-conventional mixture of fructooligosaccharides

scientific article published on 03 June 2015

An efficient method for the lipase-catalysed resolution and in-line purification of racemic flurbiprofen in a continuous-flow reactor

Biotransformation with whole microbial systems in a continuous flow reactor: resolution of (RS)-flurbiprofen using Aspergillus oryzae by direct esterification with ethanol in organic solvent

article

Design and synthesis of novel isoxazole-based HDAC inhibitors

scientific article published on 30 June 2010

Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead

scientific article published on 15 November 2013

Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria

scientific article

Drug discovery targeting amino acid racemases

scientific article

Effects of 3-Bromo-4,5-dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase-1 Expression

scientific article published on 12 October 2018

Efficient synthesis of novel glutamate homologues and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

scientific article published on 01 March 2014

Folates in Trypanosoma brucei: achievements and opportunities

scientific article published on 24 September 2018

Identification of a new series of amides as non-covalent proteasome inhibitors.

scientific article published on 25 January 2014

Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis

scientific article published on 7 May 2013

Inspired by Nature: The 3-Halo-4,5-dihydroisoxazole Moiety as a Novel Molecular Warhead for the Design of Covalent Inhibitors

scientific article

Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: design, synthesis, and pharmacological characterization

scientific article published on September 2010

One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water

Rationalizing the Lacking of Inversion Symmetry in a Noncentrosymmetric Polar Racemate: An Experimental and Theoretical Study

Regioselective Preparation of Functionalized Isoxazoline Derivatives as Key Intermediates for the Synthesis of Selective N-Methyl-d-aspartate Receptor Antagonists

Stereoselective Synthesis of 4-Amino-3-hydroxy-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-4-carboxylic Acid, a Conformationally Constrained Analogue of Aspartic Acid

article by Carlo De Micheli et al published 3 July 2007 in Synthesis

Sweet-and-salty biocatalysis: Fructooligosaccharides production using Cladosporium cladosporioides in seawater

article

Synthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

scientific article published on 16 April 2015

Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors

scientific article published on 7 October 2011

Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis

scientific article published on 2 August 2012

Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents

scientific article

Synthesis and in vitro/in vivo evaluation of the antitrypanosomal activity of 3-bromoacivicin, a potent CTP synthetase inhibitor

scientific article

Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

scholarly article by Paola Conti et al published March 2007 in Tetrahedron

Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid

scientific article

Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

scientific article published on 27 January 2007

Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors

scientific article published on 25 January 2014

Synthesis of 3-Hydroxy- and 3-Carboxy-Δ2-isoxazoline Amino Acids and Evaluation of Their Interaction with GABA Receptors and Transporters

Synthesis of 3-aryl/benzyl-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole derivatives: a comparison between conventional, microwave-assisted and flow-based methodologies

scientific article published on November 2010

Synthesis of Conformationally Constrained Glutamic Acid Homologues and Investigation of Their Pharmacological Profiles

scientific article published on 01 November 2007

Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters

Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

scientific article published on 23 December 2010

Synthesis of new β- and γ-benzyloxy-S-glutamic acid derivatives and evaluation of their activity as inhibitors of excitatory amino acid transporters

article published in 2009

Synthesis of novel pyrrolo[3,4-d]pyrazole-dicarboxylic acids and evaluation of their interaction with glutamate receptors

scientific article published in April 2008

Synthesis of unusual isoxazoline containing β and γ-dipeptides as potential glutamate receptor ligands

Use of an o-Benzyl-(S)-Serine Containing Eluent for the Efficient Ligand-Exchange Chromatography-Based Enantioseparation of Constrained Glutamate Receptor Ligands

article by Federica Ianni et al published December 2014 in Analytical Letters

List of works by Lucia Tamborini

3-Carboxy-pyrazolinalanine as a new scaffold for developing potent and selective NMDA receptor antagonists

A Base-Catalysed One-Pot Three-Component Coupling Reaction Leading to Nitrosubstituted Pyrroles

A Regioselective Route to 5-Substituted Isoxazole- and Isoxazoline-3-phosphonates

A bifurcated pathway to thiazoles and imidazoles using a modular flow microreactor

A highly efficient flow reactor process for the synthesis of N-Boc-3,4-dehydro-l-proline methyl ester

A new chemoenzymatic approach to the synthesis of Latanoprost and Bimatoprost

A novel simplified synthesis of acivicin

A regioselective route to 5-substituted pyrazole- and pyrazoline-3-phosphonic acids and esters

An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities ⬇️

An efficient continuous flow process for the synthesis of a non-conventional mixture of fructooligosaccharides

An efficient method for the lipase-catalysed resolution and in-line purification of racemic flurbiprofen in a continuous-flow reactor

Biotransformation with whole microbial systems in a continuous flow reactor: resolution of (RS)-flurbiprofen using Aspergillus oryzae by direct esterification with ethanol in organic solvent

Design and synthesis of novel isoxazole-based HDAC inhibitors

Development of rhodesain inhibitors with a 3-bromoisoxazoline warhead

Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria

Drug discovery targeting amino acid racemases

Effects of 3-Bromo-4,5-dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase-1 Expression

Efficient synthesis of novel glutamate homologues and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

Folates in Trypanosoma brucei: achievements and opportunities

Identification of a new series of amides as non-covalent proteasome inhibitors.

Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis

Inspired by Nature: The 3-Halo-4,5-dihydroisoxazole Moiety as a Novel Molecular Warhead for the Design of Covalent Inhibitors

Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: design, synthesis, and pharmacological characterization

One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water

Rationalizing the Lacking of Inversion Symmetry in a Noncentrosymmetric Polar Racemate: An Experimental and Theoretical Study

Regioselective Preparation of Functionalized Isoxazoline Derivatives as Key Intermediates for the Synthesis of Selective N-Methyl-d-aspartate Receptor Antagonists

Stereoselective Synthesis of 4-Amino-3-hydroxy-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-4-carboxylic Acid, a Conformationally Constrained Analogue of Aspartic Acid

Sweet-and-salty biocatalysis: Fructooligosaccharides production using Cladosporium cladosporioides in seawater

Synthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus

Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors

Synthesis and biological evaluation of CTP synthetase inhibitors as potential agents for the treatment of African trypanosomiasis

Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents

Synthesis and in vitro/in vivo evaluation of the antitrypanosomal activity of 3-bromoacivicin, a potent CTP synthetase inhibitor

Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid

Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors

Synthesis of 3-Hydroxy- and 3-Carboxy-Δ2-isoxazoline Amino Acids and Evaluation of Their Interaction with GABA Receptors and Transporters

Synthesis of 3-aryl/benzyl-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole derivatives: a comparison between conventional, microwave-assisted and flow-based methodologies

Synthesis of Conformationally Constrained Glutamic Acid Homologues and Investigation of Their Pharmacological Profiles

Synthesis of enantiomerically pure HIP-A and HIP-B and investigation of their activity as inhibitors of excitatory amino acid transporters

Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

Synthesis of new β- and γ-benzyloxy-S-glutamic acid derivatives and evaluation of their activity as inhibitors of excitatory amino acid transporters

Synthesis of novel pyrrolo[3,4-d]pyrazole-dicarboxylic acids and evaluation of their interaction with glutamate receptors

Synthesis of unusual isoxazoline containing β and γ-dipeptides as potential glutamate receptor ligands

Use of an o-Benzyl-(S)-Serine Containing Eluent for the Efficient Ligand-Exchange Chromatography-Based Enantioseparation of Constrained Glutamate Receptor Ligands